Detailed information of regulator


Summary

Regulator ID REG0238 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (643 a.a.); Nucleotide sequence (1929 bp)
Description Putative activators of esrB as identified by Tn-seq.
Reference

External database links

Locus tag (Gene) ETAE_0542 (slt)
Coordinates (Strand) 588958..590886 (+)
NCBI ID 502610404
RefSeq NC_013508
Uniprot ID D0ZBY8_EDWTE, A0A0H3DQ82_EDWTF
KEGG ID etd:ETAF_0492, etr:ETAE_0542
KEGG pathway (determined by BlastKOALA) -
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter -

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
SLT PF01464.22 1.3e-31 481..591
SLT_L PF14718.8 1.1e-25 403..469
Cucumo_coat PF00760.20 6.5e-06 151..203

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-642 MVMVGKWRYWSVGLCLALSAAAASADSLDAQRARYQQIKQAWDGNRMDSVNQLMPTLRDYPLYPYLAYRALTQDMSQVNAQQIKAFLQQYPTLPPARSLTSRYVNELARREDWIGLLAFSPQPPQPVAARCNYYYAQYATGHAEAAWRGAQTVWMSGQSLPSSCDKLFDAWKGAGGLRDQAILARLRLALEKGNAGLVKYLQQQLPANYQTLNTALTALQANPRSVEAFARSVAPSDFTRDIVGVAFASLARQDADAARAMLPTLVRLQHIPSSQRQAMEETIAWRLMGSDASADDRRWRDGVIRRSHNAALLERRLRMALGEGNPAQVREWLGRLPQSVRDKDEWRYWQAVALIDEGKRSEGQAILRALIKQRGFYPMVAAQRLGIPYPLQVMRAVRPDAALAQEPAIARVRELMYWNMDNTARSEWSALVASKPRPQQEALARYALDQGWADLSVQATIVAKLWDHLQERFPLAWPQEFRSATEDKGITQSYAMAIARQESAWNPEARSSVGASGLMQLMPKTAEHTAKMFSLSHYQNSSQLFDPKINIDIGTRYLEYVYQSLGRNRILASAAYNAGPSRVNTWLGNSDGRVDAVAFIESIPFSETRGYVKNVLAYDAYYRYFMHRPDQILTDAEWARRY



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
SP(Sec/SPI) 0.9876 pos: 25-26. ASA-DS. MVMVGKWRYWSVGLCLALSAAAASA



  Protein sequence of regulator: 643 a.a.    .

>REG0238 NC_013508:588958-590886 [Edwardsiella tarda EIB202]
MVMVGKWRYWSVGLCLALSAAAASADSLDAQRARYQQIKQAWDGNRMDSVNQLMPTLRDYPLYPYLAYRALTQDMSQVNA
QQIKAFLQQYPTLPPARSLTSRYVNELARREDWIGLLAFSPQPPQPVAARCNYYYAQYATGHAEAAWRGAQTVWMSGQSL
PSSCDKLFDAWKGAGGLRDQAILARLRLALEKGNAGLVKYLQQQLPANYQTLNTALTALQANPRSVEAFARSVAPSDFTR
DIVGVAFASLARQDADAARAMLPTLVRLQHIPSSQRQAMEETIAWRLMGSDASADDRRWRDGVIRRSHNAALLERRLRMA
LGEGNPAQVREWLGRLPQSVRDKDEWRYWQAVALIDEGKRSEGQAILRALIKQRGFYPMVAAQRLGIPYPLQVMRAVRPD
AALAQEPAIARVRELMYWNMDNTARSEWSALVASKPRPQQEALARYALDQGWADLSVQATIVAKLWDHLQERFPLAWPQE
FRSATEDKGITQSYAMAIARQESAWNPEARSSVGASGLMQLMPKTAEHTAKMFSLSHYQNSSQLFDPKINIDIGTRYLEY
VYQSLGRNRILASAAYNAGPSRVNTWLGNSDGRVDAVAFIESIPFSETRGYVKNVLAYDAYYRYFMHRPDQILTDAEWAR
RY*

  Nucleotide sequence of regulator: 1929 bp    .

>REG0238 NC_013508:588958-590886 [Edwardsiella tarda EIB202]
ATGGTCATGGTGGGCAAATGGCGCTATTGGAGCGTCGGGCTATGCCTCGCGCTGAGCGCGGCGGCGGCCTCGGCAGATTC
GCTCGATGCGCAGCGCGCGCGCTATCAACAGATTAAGCAGGCGTGGGACGGCAACCGGATGGACAGCGTCAATCAGCTGA
TGCCGACGCTGCGCGACTATCCGCTCTACCCCTATCTGGCTTATCGGGCTCTGACGCAGGATATGTCCCAGGTTAATGCT
CAGCAGATTAAGGCCTTTTTGCAGCAGTATCCGACGCTGCCGCCGGCGCGCAGCCTGACGTCGCGCTATGTCAATGAGCT
GGCGCGGCGCGAGGATTGGATAGGCCTGCTCGCCTTCAGTCCCCAGCCGCCGCAGCCGGTGGCGGCGCGCTGTAACTATT
ATTACGCCCAGTATGCCACGGGGCATGCGGAGGCGGCGTGGCGCGGCGCGCAGACGGTCTGGATGAGCGGTCAGTCACTG
CCCTCCAGCTGCGACAAGCTGTTCGATGCCTGGAAGGGGGCCGGTGGGCTACGGGATCAGGCGATACTGGCTCGTCTGCG
TCTGGCGCTGGAAAAAGGCAACGCGGGGCTGGTGAAATACCTGCAGCAGCAGCTGCCGGCGAATTACCAGACCCTGAATA
CCGCGCTGACGGCGCTGCAGGCCAATCCGCGCAGCGTAGAGGCCTTTGCCCGCAGCGTTGCGCCGAGCGATTTTACCCGC
GATATCGTGGGGGTCGCCTTTGCCTCGCTGGCGCGTCAGGATGCGGACGCCGCGCGGGCGATGCTGCCCACGCTGGTGCG
TCTGCAGCATATTCCGTCGAGTCAGCGGCAGGCGATGGAGGAGACCATTGCCTGGCGACTGATGGGCAGCGACGCCAGCG
CCGACGATCGCCGCTGGCGCGACGGCGTGATCCGCCGCAGCCATAATGCGGCGTTGCTGGAGCGACGTCTGCGTATGGCG
CTGGGCGAGGGCAATCCGGCGCAGGTGCGCGAATGGCTGGGGCGTTTACCGCAGTCGGTGCGTGATAAGGATGAATGGCG
CTATTGGCAAGCGGTGGCGCTGATAGATGAGGGTAAGCGCAGCGAGGGGCAGGCGATTCTGCGGGCGCTGATCAAGCAGC
GCGGCTTTTATCCGATGGTGGCCGCCCAGCGGCTGGGTATTCCCTATCCGCTGCAGGTGATGCGCGCGGTACGCCCGGAT
GCCGCCCTGGCGCAGGAGCCAGCGATCGCCCGCGTGCGTGAGCTGATGTACTGGAATATGGATAATACCGCGCGCAGTGA
GTGGAGCGCGCTGGTCGCCAGCAAGCCTCGTCCCCAGCAGGAGGCGCTGGCGCGCTATGCCCTGGATCAGGGCTGGGCCG
ATCTGAGCGTGCAGGCGACGATTGTGGCGAAGCTGTGGGATCATCTGCAGGAGCGATTCCCGCTGGCCTGGCCGCAGGAG
TTTCGCAGCGCAACCGAGGATAAGGGGATCACCCAAAGCTATGCCATGGCCATCGCCCGCCAGGAGAGCGCCTGGAACCC
AGAGGCGCGTTCCTCGGTCGGCGCCAGCGGTCTGATGCAGCTGATGCCGAAGACCGCTGAGCACACGGCCAAGATGTTCA
GCCTGAGTCACTATCAAAACAGCAGCCAGCTGTTCGATCCAAAAATCAATATCGATATTGGTACCCGTTACCTGGAGTAC
GTCTACCAGAGCCTGGGGCGTAACCGTATTCTGGCGAGCGCCGCCTACAACGCGGGGCCGTCGCGGGTGAATACCTGGCT
CGGCAACAGCGACGGGCGGGTAGATGCGGTGGCGTTTATCGAGAGCATTCCGTTTTCGGAGACGCGTGGCTACGTGAAGA
ACGTATTAGCCTATGATGCCTACTATCGCTATTTCATGCATCGACCGGATCAGATACTGACGGACGCCGAGTGGGCGCGT
CGCTACTAG