Detailed information of regulator
Summary
Regulator ID | REG0238 |
Regulator type | protein |
Regulatory pathway (from literatures) | TCS regulatory pathway |
KEGG pathway (determined by BlastKOALA) | - |
Related T6SS | T6SS00372 (Type i4b) |
Strain | Edwardsiella tarda EIB202 |
Replicon | chromosome |
Sequence | Protein sequence (643 a.a.); Nucleotide sequence (1929 bp) |
Description | Putative activators of esrB as identified by Tn-seq. |
Reference |
External database links
Locus tag (Gene) | ETAE_0542 (slt) |
Coordinates (Strand) | 588958..590886 (+) |
NCBI ID | 502610404 |
RefSeq | NC_013508 |
Uniprot ID | D0ZBY8_EDWTE, A0A0H3DQ82_EDWTF |
KEGG ID | etd:ETAF_0492, etr:ETAE_0542 |
KEGG pathway (determined by BlastKOALA) | - |
PDB ID | - |
Target
Target | Regulation (↓/↑) | Target sequence |
---|---|---|
ETAE_0886 (esrB) promoter | ↓ | - |
Pfam domain hit(s) of regulator
Domain | Pfam ID | E-value | Aligned region |
---|---|---|---|
SLT | PF01464.22 | 1.3e-31 | 481..591 |
SLT_L | PF14718.8 | 1.1e-25 | 403..469 |
Cucumo_coat | PF00760.20 | 6.5e-06 | 151..203 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
Prediction | Region | Sequence |
---|---|---|
Outside | 1-642 | MVMVGKWRYWSVGLCLALSAAAASADSLDAQRARYQQIKQAWDGNRMDSVNQLMPTLRDYPLYPYLAYRALTQDMSQVNAQQIKAFLQQYPTLPPARSLTSRYVNELARREDWIGLLAFSPQPPQPVAARCNYYYAQYATGHAEAAWRGAQTVWMSGQSLPSSCDKLFDAWKGAGGLRDQAILARLRLALEKGNAGLVKYLQQQLPANYQTLNTALTALQANPRSVEAFARSVAPSDFTRDIVGVAFASLARQDADAARAMLPTLVRLQHIPSSQRQAMEETIAWRLMGSDASADDRRWRDGVIRRSHNAALLERRLRMALGEGNPAQVREWLGRLPQSVRDKDEWRYWQAVALIDEGKRSEGQAILRALIKQRGFYPMVAAQRLGIPYPLQVMRAVRPDAALAQEPAIARVRELMYWNMDNTARSEWSALVASKPRPQQEALARYALDQGWADLSVQATIVAKLWDHLQERFPLAWPQEFRSATEDKGITQSYAMAIARQESAWNPEARSSVGASGLMQLMPKTAEHTAKMFSLSHYQNSSQLFDPKINIDIGTRYLEYVYQSLGRNRILASAAYNAGPSRVNTWLGNSDGRVDAVAFIESIPFSETRGYVKNVLAYDAYYRYFMHRPDQILTDAEWARRY |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction | Probability | Cleavage site | Signal peptide sequence |
---|---|---|---|
SP(Sec/SPI) | 0.9876 | pos: 25-26. ASA-DS. | MVMVGKWRYWSVGLCLALSAAAASA |
Protein sequence of regulator: 643 a.a. .
>REG0238 NC_013508:588958-590886 [Edwardsiella tarda EIB202]
MVMVGKWRYWSVGLCLALSAAAASADSLDAQRARYQQIKQAWDGNRMDSVNQLMPTLRDYPLYPYLAYRALTQDMSQVNA
QQIKAFLQQYPTLPPARSLTSRYVNELARREDWIGLLAFSPQPPQPVAARCNYYYAQYATGHAEAAWRGAQTVWMSGQSL
PSSCDKLFDAWKGAGGLRDQAILARLRLALEKGNAGLVKYLQQQLPANYQTLNTALTALQANPRSVEAFARSVAPSDFTR
DIVGVAFASLARQDADAARAMLPTLVRLQHIPSSQRQAMEETIAWRLMGSDASADDRRWRDGVIRRSHNAALLERRLRMA
LGEGNPAQVREWLGRLPQSVRDKDEWRYWQAVALIDEGKRSEGQAILRALIKQRGFYPMVAAQRLGIPYPLQVMRAVRPD
AALAQEPAIARVRELMYWNMDNTARSEWSALVASKPRPQQEALARYALDQGWADLSVQATIVAKLWDHLQERFPLAWPQE
FRSATEDKGITQSYAMAIARQESAWNPEARSSVGASGLMQLMPKTAEHTAKMFSLSHYQNSSQLFDPKINIDIGTRYLEY
VYQSLGRNRILASAAYNAGPSRVNTWLGNSDGRVDAVAFIESIPFSETRGYVKNVLAYDAYYRYFMHRPDQILTDAEWAR
RY*
MVMVGKWRYWSVGLCLALSAAAASADSLDAQRARYQQIKQAWDGNRMDSVNQLMPTLRDYPLYPYLAYRALTQDMSQVNA
QQIKAFLQQYPTLPPARSLTSRYVNELARREDWIGLLAFSPQPPQPVAARCNYYYAQYATGHAEAAWRGAQTVWMSGQSL
PSSCDKLFDAWKGAGGLRDQAILARLRLALEKGNAGLVKYLQQQLPANYQTLNTALTALQANPRSVEAFARSVAPSDFTR
DIVGVAFASLARQDADAARAMLPTLVRLQHIPSSQRQAMEETIAWRLMGSDASADDRRWRDGVIRRSHNAALLERRLRMA
LGEGNPAQVREWLGRLPQSVRDKDEWRYWQAVALIDEGKRSEGQAILRALIKQRGFYPMVAAQRLGIPYPLQVMRAVRPD
AALAQEPAIARVRELMYWNMDNTARSEWSALVASKPRPQQEALARYALDQGWADLSVQATIVAKLWDHLQERFPLAWPQE
FRSATEDKGITQSYAMAIARQESAWNPEARSSVGASGLMQLMPKTAEHTAKMFSLSHYQNSSQLFDPKINIDIGTRYLEY
VYQSLGRNRILASAAYNAGPSRVNTWLGNSDGRVDAVAFIESIPFSETRGYVKNVLAYDAYYRYFMHRPDQILTDAEWAR
RY*
Nucleotide sequence of regulator: 1929 bp .
>REG0238 NC_013508:588958-590886 [Edwardsiella tarda EIB202]
ATGGTCATGGTGGGCAAATGGCGCTATTGGAGCGTCGGGCTATGCCTCGCGCTGAGCGCGGCGGCGGCCTCGGCAGATTC
GCTCGATGCGCAGCGCGCGCGCTATCAACAGATTAAGCAGGCGTGGGACGGCAACCGGATGGACAGCGTCAATCAGCTGA
TGCCGACGCTGCGCGACTATCCGCTCTACCCCTATCTGGCTTATCGGGCTCTGACGCAGGATATGTCCCAGGTTAATGCT
CAGCAGATTAAGGCCTTTTTGCAGCAGTATCCGACGCTGCCGCCGGCGCGCAGCCTGACGTCGCGCTATGTCAATGAGCT
GGCGCGGCGCGAGGATTGGATAGGCCTGCTCGCCTTCAGTCCCCAGCCGCCGCAGCCGGTGGCGGCGCGCTGTAACTATT
ATTACGCCCAGTATGCCACGGGGCATGCGGAGGCGGCGTGGCGCGGCGCGCAGACGGTCTGGATGAGCGGTCAGTCACTG
CCCTCCAGCTGCGACAAGCTGTTCGATGCCTGGAAGGGGGCCGGTGGGCTACGGGATCAGGCGATACTGGCTCGTCTGCG
TCTGGCGCTGGAAAAAGGCAACGCGGGGCTGGTGAAATACCTGCAGCAGCAGCTGCCGGCGAATTACCAGACCCTGAATA
CCGCGCTGACGGCGCTGCAGGCCAATCCGCGCAGCGTAGAGGCCTTTGCCCGCAGCGTTGCGCCGAGCGATTTTACCCGC
GATATCGTGGGGGTCGCCTTTGCCTCGCTGGCGCGTCAGGATGCGGACGCCGCGCGGGCGATGCTGCCCACGCTGGTGCG
TCTGCAGCATATTCCGTCGAGTCAGCGGCAGGCGATGGAGGAGACCATTGCCTGGCGACTGATGGGCAGCGACGCCAGCG
CCGACGATCGCCGCTGGCGCGACGGCGTGATCCGCCGCAGCCATAATGCGGCGTTGCTGGAGCGACGTCTGCGTATGGCG
CTGGGCGAGGGCAATCCGGCGCAGGTGCGCGAATGGCTGGGGCGTTTACCGCAGTCGGTGCGTGATAAGGATGAATGGCG
CTATTGGCAAGCGGTGGCGCTGATAGATGAGGGTAAGCGCAGCGAGGGGCAGGCGATTCTGCGGGCGCTGATCAAGCAGC
GCGGCTTTTATCCGATGGTGGCCGCCCAGCGGCTGGGTATTCCCTATCCGCTGCAGGTGATGCGCGCGGTACGCCCGGAT
GCCGCCCTGGCGCAGGAGCCAGCGATCGCCCGCGTGCGTGAGCTGATGTACTGGAATATGGATAATACCGCGCGCAGTGA
GTGGAGCGCGCTGGTCGCCAGCAAGCCTCGTCCCCAGCAGGAGGCGCTGGCGCGCTATGCCCTGGATCAGGGCTGGGCCG
ATCTGAGCGTGCAGGCGACGATTGTGGCGAAGCTGTGGGATCATCTGCAGGAGCGATTCCCGCTGGCCTGGCCGCAGGAG
TTTCGCAGCGCAACCGAGGATAAGGGGATCACCCAAAGCTATGCCATGGCCATCGCCCGCCAGGAGAGCGCCTGGAACCC
AGAGGCGCGTTCCTCGGTCGGCGCCAGCGGTCTGATGCAGCTGATGCCGAAGACCGCTGAGCACACGGCCAAGATGTTCA
GCCTGAGTCACTATCAAAACAGCAGCCAGCTGTTCGATCCAAAAATCAATATCGATATTGGTACCCGTTACCTGGAGTAC
GTCTACCAGAGCCTGGGGCGTAACCGTATTCTGGCGAGCGCCGCCTACAACGCGGGGCCGTCGCGGGTGAATACCTGGCT
CGGCAACAGCGACGGGCGGGTAGATGCGGTGGCGTTTATCGAGAGCATTCCGTTTTCGGAGACGCGTGGCTACGTGAAGA
ACGTATTAGCCTATGATGCCTACTATCGCTATTTCATGCATCGACCGGATCAGATACTGACGGACGCCGAGTGGGCGCGT
CGCTACTAG
ATGGTCATGGTGGGCAAATGGCGCTATTGGAGCGTCGGGCTATGCCTCGCGCTGAGCGCGGCGGCGGCCTCGGCAGATTC
GCTCGATGCGCAGCGCGCGCGCTATCAACAGATTAAGCAGGCGTGGGACGGCAACCGGATGGACAGCGTCAATCAGCTGA
TGCCGACGCTGCGCGACTATCCGCTCTACCCCTATCTGGCTTATCGGGCTCTGACGCAGGATATGTCCCAGGTTAATGCT
CAGCAGATTAAGGCCTTTTTGCAGCAGTATCCGACGCTGCCGCCGGCGCGCAGCCTGACGTCGCGCTATGTCAATGAGCT
GGCGCGGCGCGAGGATTGGATAGGCCTGCTCGCCTTCAGTCCCCAGCCGCCGCAGCCGGTGGCGGCGCGCTGTAACTATT
ATTACGCCCAGTATGCCACGGGGCATGCGGAGGCGGCGTGGCGCGGCGCGCAGACGGTCTGGATGAGCGGTCAGTCACTG
CCCTCCAGCTGCGACAAGCTGTTCGATGCCTGGAAGGGGGCCGGTGGGCTACGGGATCAGGCGATACTGGCTCGTCTGCG
TCTGGCGCTGGAAAAAGGCAACGCGGGGCTGGTGAAATACCTGCAGCAGCAGCTGCCGGCGAATTACCAGACCCTGAATA
CCGCGCTGACGGCGCTGCAGGCCAATCCGCGCAGCGTAGAGGCCTTTGCCCGCAGCGTTGCGCCGAGCGATTTTACCCGC
GATATCGTGGGGGTCGCCTTTGCCTCGCTGGCGCGTCAGGATGCGGACGCCGCGCGGGCGATGCTGCCCACGCTGGTGCG
TCTGCAGCATATTCCGTCGAGTCAGCGGCAGGCGATGGAGGAGACCATTGCCTGGCGACTGATGGGCAGCGACGCCAGCG
CCGACGATCGCCGCTGGCGCGACGGCGTGATCCGCCGCAGCCATAATGCGGCGTTGCTGGAGCGACGTCTGCGTATGGCG
CTGGGCGAGGGCAATCCGGCGCAGGTGCGCGAATGGCTGGGGCGTTTACCGCAGTCGGTGCGTGATAAGGATGAATGGCG
CTATTGGCAAGCGGTGGCGCTGATAGATGAGGGTAAGCGCAGCGAGGGGCAGGCGATTCTGCGGGCGCTGATCAAGCAGC
GCGGCTTTTATCCGATGGTGGCCGCCCAGCGGCTGGGTATTCCCTATCCGCTGCAGGTGATGCGCGCGGTACGCCCGGAT
GCCGCCCTGGCGCAGGAGCCAGCGATCGCCCGCGTGCGTGAGCTGATGTACTGGAATATGGATAATACCGCGCGCAGTGA
GTGGAGCGCGCTGGTCGCCAGCAAGCCTCGTCCCCAGCAGGAGGCGCTGGCGCGCTATGCCCTGGATCAGGGCTGGGCCG
ATCTGAGCGTGCAGGCGACGATTGTGGCGAAGCTGTGGGATCATCTGCAGGAGCGATTCCCGCTGGCCTGGCCGCAGGAG
TTTCGCAGCGCAACCGAGGATAAGGGGATCACCCAAAGCTATGCCATGGCCATCGCCCGCCAGGAGAGCGCCTGGAACCC
AGAGGCGCGTTCCTCGGTCGGCGCCAGCGGTCTGATGCAGCTGATGCCGAAGACCGCTGAGCACACGGCCAAGATGTTCA
GCCTGAGTCACTATCAAAACAGCAGCCAGCTGTTCGATCCAAAAATCAATATCGATATTGGTACCCGTTACCTGGAGTAC
GTCTACCAGAGCCTGGGGCGTAACCGTATTCTGGCGAGCGCCGCCTACAACGCGGGGCCGTCGCGGGTGAATACCTGGCT
CGGCAACAGCGACGGGCGGGTAGATGCGGTGGCGTTTATCGAGAGCATTCCGTTTTCGGAGACGCGTGGCTACGTGAAGA
ACGTATTAGCCTATGATGCCTACTATCGCTATTTCATGCATCGACCGGATCAGATACTGACGGACGCCGAGTGGGCGCGT
CGCTACTAG