Detailed information of regulator


Summary

Regulator ID REG0086 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00016 experimental (Type i5)
Strain Agrobacterium fabrum str. C58
Replicon chromosome
Sequence Protein sequence (265 a.a.); Nucleotide sequence (795 bp)
Description Lack of exoR enhanced the expression of both imp and hcp operons and deletion of chvG in the ΔexoR mutant background abrogated the induced expression of imp and hcp operons.ExoR–ChvG interaction regulates ChvG protein level and T6SS expression/secretion.
Reference
External database links

Locus tag (Gene) exoR
Coordinates (Strand) 1702398..1703192 (-)
NCBI ID
RefSeq NC_003062
Uniprot ID -
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
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Target
Regulation (↓/↑)
Target sequence
chvG↑-
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Pfam domain hit(s) of regulator

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Domain
Pfam ID
E-value
Aligned region
Sel1PF08238.141.1e-06158..193
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Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction                
Region    
Sequence
Inside1-11MLKCEANVLKP
Transmembrane helix12-34LLMGMLLASLAMPVLAFDINAGV
Outside35-264TKESGPFDLFKFGFKAYKNGNKDEAVEAYRYAAEKGHTGSRWALANMYAYGDGVAKNDLEAFKIYSEIASQGVEPGSEDTGFFVNALLSLADYYRHGIPGSPVKMDLSQARQLYFQVASTFGVAEAQFRLAEMILAGEGGRADVQQAKKWLNQARKHGHAGAMSIFGNLIFQEGQTTQGLAFMTAALDKCTVADCTWIQNLQEQAFSLAGENDRRAAIAMAQNMQFNDPD


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction       
Probability
Cleavage site
Signal peptide sequence
SP(Sec/SPI)0.9898pos: 27-28. VLA-FD.MLKCEANVLKPLLMGMLLASLAMPVLA


  Protein sequence of regulator: 265 a.a.    .

>REG0086 NC_003062:c1703192-1702398 [Agrobacterium fabrum str. C58]
MLKCEANVLKPLLMGMLLASLAMPVLAFDINAGVTKESGPFDLFKFGFKAYKNGNKDEAVEAYRYAAEKGHTGSRWALAN
MYAYGDGVAKNDLEAFKIYSEIASQGVEPGSEDTGFFVNALLSLADYYRHGIPGSPVKMDLSQARQLYFQVASTFGVAEA
QFRLAEMILAGEGGRADVQQAKKWLNQARKHGHAGAMSIFGNLIFQEGQTTQGLAFMTAALDKCTVADCTWIQNLQEQAF
SLAGENDRRAAIAMAQNMQFNDPD*

  Nucleotide sequence of regulator: 795 bp    .

>REG0086 NC_003062:c1703192-1702398 [Agrobacterium fabrum str. C58]
ATGCTGAAATGTGAAGCCAACGTTTTAAAGCCGCTCCTTATGGGCATGTTGCTTGCGTCGCTCGCAATGCCGGTGCTGGC
TTTTGACATTAATGCGGGCGTGACCAAGGAATCCGGCCCCTTCGACCTGTTCAAGTTTGGCTTCAAGGCCTACAAGAACG
GCAACAAGGACGAAGCCGTCGAGGCCTATCGTTATGCGGCGGAAAAGGGCCATACCGGCTCGCGCTGGGCGCTTGCCAAT
ATGTATGCCTATGGCGACGGTGTCGCCAAGAACGATCTGGAAGCTTTCAAGATCTACAGCGAAATCGCCAGTCAGGGTGT
GGAGCCGGGTTCGGAAGATACCGGCTTCTTCGTCAACGCCCTTCTTTCCCTTGCCGATTATTACCGTCACGGCATTCCCG
GCAGCCCCGTGAAAATGGACCTATCACAGGCCCGTCAGCTTTATTTCCAGGTGGCTTCCACCTTTGGCGTGGCTGAAGCG
CAGTTCCGGCTGGCGGAGATGATCCTCGCGGGCGAGGGTGGCCGCGCCGATGTGCAGCAGGCGAAGAAGTGGCTCAACCA
GGCCCGCAAGCACGGCCATGCCGGCGCCATGTCGATTTTCGGCAACCTGATCTTCCAGGAAGGCCAGACGACGCAGGGGC
TGGCCTTCATGACGGCGGCACTTGATAAGTGCACGGTGGCCGACTGTACCTGGATCCAGAACCTGCAGGAGCAGGCCTTT
TCTCTCGCCGGTGAAAACGACCGCCGCGCCGCCATCGCCATGGCGCAGAACATGCAGTTCAACGATCCGGATTGA