Detailed information of regulator
Summary
Regulator ID | REG0086 |
Regulator type | protein |
Regulatory pathway (from literatures) | TCS regulatory pathway |
KEGG pathway (determined by BlastKOALA) | - |
Related T6SS | T6SS00016 (Type i5) |
Strain | Agrobacterium fabrum str. C58 |
Replicon | chromosome |
Sequence | Protein sequence (265 a.a.); Nucleotide sequence (795 bp) |
Description | Lack of exoR enhanced the expression of both imp and hcp operons and deletion of chvG in the ΔexoR mutant background abrogated the induced expression of imp and hcp operons.ExoR–ChvG interaction regulates ChvG protein level and T6SS expression/secretion. |
Reference |
External database links
Locus tag (Gene) | exoR |
Coordinates (Strand) | 1702398..1703192 (-) |
NCBI ID | |
RefSeq | NC_003062 |
Uniprot ID | - |
KEGG ID | - |
KEGG pathway (determined by BlastKOALA) | - |
PDB ID | - |
Target
Target | Regulation (↓/↑) | Target sequence |
---|---|---|
chvG | ↑ | - |
Pfam domain hit(s) of regulator
Domain | Pfam ID | E-value | Aligned region |
---|---|---|---|
Sel1 | PF08238.14 | 1.1e-06 | 158..193 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
Prediction | Region | Sequence |
---|---|---|
Inside | 1-11 | MLKCEANVLKP |
Transmembrane helix | 12-34 | LLMGMLLASLAMPVLAFDINAGV |
Outside | 35-264 | TKESGPFDLFKFGFKAYKNGNKDEAVEAYRYAAEKGHTGSRWALANMYAYGDGVAKNDLEAFKIYSEIASQGVEPGSEDTGFFVNALLSLADYYRHGIPGSPVKMDLSQARQLYFQVASTFGVAEAQFRLAEMILAGEGGRADVQQAKKWLNQARKHGHAGAMSIFGNLIFQEGQTTQGLAFMTAALDKCTVADCTWIQNLQEQAFSLAGENDRRAAIAMAQNMQFNDPD |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction | Probability | Cleavage site | Signal peptide sequence |
---|---|---|---|
SP(Sec/SPI) | 0.9898 | pos: 27-28. VLA-FD. | MLKCEANVLKPLLMGMLLASLAMPVLA |
Protein sequence of regulator: 265 a.a. .
>REG0086 NC_003062:c1703192-1702398 [Agrobacterium fabrum str. C58]
MLKCEANVLKPLLMGMLLASLAMPVLAFDINAGVTKESGPFDLFKFGFKAYKNGNKDEAVEAYRYAAEKGHTGSRWALAN
MYAYGDGVAKNDLEAFKIYSEIASQGVEPGSEDTGFFVNALLSLADYYRHGIPGSPVKMDLSQARQLYFQVASTFGVAEA
QFRLAEMILAGEGGRADVQQAKKWLNQARKHGHAGAMSIFGNLIFQEGQTTQGLAFMTAALDKCTVADCTWIQNLQEQAF
SLAGENDRRAAIAMAQNMQFNDPD*
MLKCEANVLKPLLMGMLLASLAMPVLAFDINAGVTKESGPFDLFKFGFKAYKNGNKDEAVEAYRYAAEKGHTGSRWALAN
MYAYGDGVAKNDLEAFKIYSEIASQGVEPGSEDTGFFVNALLSLADYYRHGIPGSPVKMDLSQARQLYFQVASTFGVAEA
QFRLAEMILAGEGGRADVQQAKKWLNQARKHGHAGAMSIFGNLIFQEGQTTQGLAFMTAALDKCTVADCTWIQNLQEQAF
SLAGENDRRAAIAMAQNMQFNDPD*
Nucleotide sequence of regulator: 795 bp .
>REG0086 NC_003062:c1703192-1702398 [Agrobacterium fabrum str. C58]
ATGCTGAAATGTGAAGCCAACGTTTTAAAGCCGCTCCTTATGGGCATGTTGCTTGCGTCGCTCGCAATGCCGGTGCTGGC
TTTTGACATTAATGCGGGCGTGACCAAGGAATCCGGCCCCTTCGACCTGTTCAAGTTTGGCTTCAAGGCCTACAAGAACG
GCAACAAGGACGAAGCCGTCGAGGCCTATCGTTATGCGGCGGAAAAGGGCCATACCGGCTCGCGCTGGGCGCTTGCCAAT
ATGTATGCCTATGGCGACGGTGTCGCCAAGAACGATCTGGAAGCTTTCAAGATCTACAGCGAAATCGCCAGTCAGGGTGT
GGAGCCGGGTTCGGAAGATACCGGCTTCTTCGTCAACGCCCTTCTTTCCCTTGCCGATTATTACCGTCACGGCATTCCCG
GCAGCCCCGTGAAAATGGACCTATCACAGGCCCGTCAGCTTTATTTCCAGGTGGCTTCCACCTTTGGCGTGGCTGAAGCG
CAGTTCCGGCTGGCGGAGATGATCCTCGCGGGCGAGGGTGGCCGCGCCGATGTGCAGCAGGCGAAGAAGTGGCTCAACCA
GGCCCGCAAGCACGGCCATGCCGGCGCCATGTCGATTTTCGGCAACCTGATCTTCCAGGAAGGCCAGACGACGCAGGGGC
TGGCCTTCATGACGGCGGCACTTGATAAGTGCACGGTGGCCGACTGTACCTGGATCCAGAACCTGCAGGAGCAGGCCTTT
TCTCTCGCCGGTGAAAACGACCGCCGCGCCGCCATCGCCATGGCGCAGAACATGCAGTTCAACGATCCGGATTGA
ATGCTGAAATGTGAAGCCAACGTTTTAAAGCCGCTCCTTATGGGCATGTTGCTTGCGTCGCTCGCAATGCCGGTGCTGGC
TTTTGACATTAATGCGGGCGTGACCAAGGAATCCGGCCCCTTCGACCTGTTCAAGTTTGGCTTCAAGGCCTACAAGAACG
GCAACAAGGACGAAGCCGTCGAGGCCTATCGTTATGCGGCGGAAAAGGGCCATACCGGCTCGCGCTGGGCGCTTGCCAAT
ATGTATGCCTATGGCGACGGTGTCGCCAAGAACGATCTGGAAGCTTTCAAGATCTACAGCGAAATCGCCAGTCAGGGTGT
GGAGCCGGGTTCGGAAGATACCGGCTTCTTCGTCAACGCCCTTCTTTCCCTTGCCGATTATTACCGTCACGGCATTCCCG
GCAGCCCCGTGAAAATGGACCTATCACAGGCCCGTCAGCTTTATTTCCAGGTGGCTTCCACCTTTGGCGTGGCTGAAGCG
CAGTTCCGGCTGGCGGAGATGATCCTCGCGGGCGAGGGTGGCCGCGCCGATGTGCAGCAGGCGAAGAAGTGGCTCAACCA
GGCCCGCAAGCACGGCCATGCCGGCGCCATGTCGATTTTCGGCAACCTGATCTTCCAGGAAGGCCAGACGACGCAGGGGC
TGGCCTTCATGACGGCGGCACTTGATAAGTGCACGGTGGCCGACTGTACCTGGATCCAGAACCTGCAGGAGCAGGCCTTT
TCTCTCGCCGGTGAAAACGACCGCCGCGCCGCCATCGCCATGGCGCAGAACATGCAGTTCAACGATCCGGATTGA