Detailed information of regulator
Summary
| Regulator ID | REG0219  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (108 a.a.); Nucleotide sequence (324 bp) |
| Description | Putative repressors of esrB as identified by Tn-seq. |
| Reference |
External database links
| Locus tag (Gene) | ETAE_2813 (iscA) |
| Coordinates (Strand) | 2952011..2952334 (-) |
| NCBI ID | 491431780 |
| RefSeq | NC_013508 |
| Uniprot ID | A0A034T030_9GAMM, D0ZD84_EDWTE, D4F959_EDWTA, A0A2A7U0J8_EDWTA, A0A076LLA6_9GAMM, A0A0H3DVW2_EDWTF |
| KEGG ID | ete:ETEE_1033, etd:ETAF_2552, etr:ETAE_2813 |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| ETAE_0886 (esrB) promoter | ↑ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| Fe-S_biosyn | PF01521.22 | 4.7e-26 | 1..103 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-107 | MSITMSDSAAKRVQTFLTNRGKGLGLRLGVKTSGCSGMAYVLEFVDVLNEDDVVFEDKGVKVIVDGKSLVYLDGTELDFVKEGLNEGFKFNNPNVKNECGCGESFNV |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9294 | - | - |
Protein sequence of regulator: 108 a.a. .
>REG0219 NC_013508:c2952334-2952011 [Edwardsiella tarda EIB202]
MSITMSDSAAKRVQTFLTNRGKGLGLRLGVKTSGCSGMAYVLEFVDVLNEDDVVFEDKGVKVIVDGKSLVYLDGTELDFV
KEGLNEGFKFNNPNVKNECGCGESFNV*
MSITMSDSAAKRVQTFLTNRGKGLGLRLGVKTSGCSGMAYVLEFVDVLNEDDVVFEDKGVKVIVDGKSLVYLDGTELDFV
KEGLNEGFKFNNPNVKNECGCGESFNV*
Nucleotide sequence of regulator: 324 bp .
>REG0219 NC_013508:c2952334-2952011 [Edwardsiella tarda EIB202]
ATGTCGATTACCATGAGCGACTCCGCTGCAAAGCGCGTACAGACATTTTTAACCAATCGCGGTAAGGGATTGGGCCTGCG
TCTGGGGGTAAAAACCTCGGGCTGTTCGGGCATGGCGTATGTGCTGGAGTTTGTCGATGTCCTGAACGAGGACGATGTGG
TTTTCGAGGATAAAGGGGTGAAGGTCATCGTTGACGGAAAGAGCCTGGTGTACCTCGACGGTACCGAGCTGGATTTCGTT
AAAGAGGGCCTGAACGAAGGCTTTAAGTTCAACAACCCGAACGTTAAGAATGAGTGCGGCTGCGGCGAGAGCTTTAACGT
TTAA
ATGTCGATTACCATGAGCGACTCCGCTGCAAAGCGCGTACAGACATTTTTAACCAATCGCGGTAAGGGATTGGGCCTGCG
TCTGGGGGTAAAAACCTCGGGCTGTTCGGGCATGGCGTATGTGCTGGAGTTTGTCGATGTCCTGAACGAGGACGATGTGG
TTTTCGAGGATAAAGGGGTGAAGGTCATCGTTGACGGAAAGAGCCTGGTGTACCTCGACGGTACCGAGCTGGATTTCGTT
AAAGAGGGCCTGAACGAAGGCTTTAAGTTCAACAACCCGAACGTTAAGAATGAGTGCGGCTGCGGCGAGAGCTTTAACGT
TTAA