Detailed information of regulator


Summary

Regulator ID REG0227 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) Cell cycle - Caulobacter (map04112)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (742 a.a.); Nucleotide sequence (2226 bp)
Description RpoS is regulated by Lon and mediates control of esrB expression.
Reference
External database links

Locus tag (Gene) ETAE_0994 (Lon)
Coordinates (Strand) 1085063..1087288 (+)
NCBI ID 267984010
RefSeq NC_013508
Uniprot ID D0ZEA8_EDWTE
KEGG ID etr:ETAE_0994
KEGG pathway (determined by BlastKOALA) map04112
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter ↓ 502612732
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
Lon_C PF05362.15 4.1e-98 527..729
LON_substr_bdg PF02190.18 1.5e-29 3..158
AAA PF00004.31 6.2e-17 309..446
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-741 MDHDKKILLVAQKEASTDEPGINDLFTVGTVASILQMLKLPDGTVKVLVEGIQRARITTLSDGGEHFAAQAEYLDTPEMEEREQEVLVRTAINQFESYIKLNKKIPPEVLTSLNSIDDAARLADTIAAHMPLKLNDKQTVLEMSDVAERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPDEFEALKRKIEAAKMPKEAREKAESELQKLKMMSPMSAEATVVRSYIDWIVQVPWHARSKVKKDLRKAQETLDADHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIARATGRQYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVRNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIARQHLLPKQIERNALKKGELTVDDSAIVGIIRYYTREAGVRALEREISKLCRKAVKQLLLDKSLRHIEINGDNLKDYLGVQRFDYGRADSENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPDDNKRDLEEMPENVLRDLDIHPVKRIDEVLALALQNSPFGMDVVTAK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9940 - -


  Protein sequence of regulator: 742 a.a.    .

>REG0227 NC_013508:1085063-1087288 [Edwardsiella tarda EIB202]
MDHDKKILLVAQKEASTDEPGINDLFTVGTVASILQMLKLPDGTVKVLVEGIQRARITTLSDGGEHFAAQAEYLDTPEME
EREQEVLVRTAINQFESYIKLNKKIPPEVLTSLNSIDDAARLADTIAAHMPLKLNDKQTVLEMSDVAERLEYLMAMMESE
IDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPDEFEALKRKIEAAKMPKEAREKAESELQKLKMMSP
MSAEATVVRSYIDWIVQVPWHARSKVKKDLRKAQETLDADHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKT
SLGQSIARATGRQYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVRNPLFLLDEIDKMSSDMRGDPASALLEV
LDPEQNVAFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIARQHLLPKQIERNALKKGELTV
DDSAIVGIIRYYTREAGVRALEREISKLCRKAVKQLLLDKSLRHIEINGDNLKDYLGVQRFDYGRADSENRVGQVTGLAW
TEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIA
MCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPDDNKRDLEEMPENVLRDLDIHPVKRI
DEVLALALQNSPFGMDVVTAK*

  Nucleotide sequence of regulator: 2226 bp    .

>REG0227 NC_013508:1085063-1087288 [Edwardsiella tarda EIB202]
ATGGATCACGACAAGAAGATCCTGCTGGTGGCGCAAAAAGAGGCCTCGACCGATGAGCCGGGGATCAACGATCTGTTTAC
GGTCGGCACGGTAGCCTCCATTCTGCAGATGCTGAAGCTGCCCGATGGCACGGTAAAAGTGCTGGTTGAAGGGATCCAGC
GCGCGCGCATTACCACACTGTCTGACGGCGGCGAACACTTTGCTGCCCAGGCGGAGTACCTGGATACGCCGGAGATGGAG
GAGCGCGAGCAAGAGGTTCTGGTTCGCACCGCCATCAATCAGTTTGAAAGCTATATCAAGCTGAACAAAAAAATTCCGCC
GGAGGTGCTGACGTCGCTGAACAGCATCGACGACGCCGCCCGTCTGGCCGACACTATCGCCGCCCATATGCCGCTGAAGC
TGAACGATAAGCAGACGGTACTGGAGATGTCCGACGTGGCGGAGCGTCTGGAATACCTGATGGCGATGATGGAGTCCGAG
ATCGATCTGCTGCAGGTAGAAAAACGCATCCGTAACCGGGTGAAGAAGCAGATGGAGAAGAGCCAGCGCGAGTATTATCT
GAATGAGCAGATGAAAGCGATTCAGAAAGAGCTCGGCGAAATGGACGACGCGCCGGATGAGTTTGAGGCCCTGAAGCGCA
AGATAGAAGCGGCCAAAATGCCGAAAGAGGCGCGCGAGAAGGCGGAGTCCGAGCTACAGAAGCTGAAGATGATGTCGCCG
ATGTCGGCGGAAGCGACCGTGGTGCGCAGCTATATCGACTGGATTGTGCAGGTGCCGTGGCATGCGCGCAGCAAGGTGAA
AAAAGATCTGCGCAAAGCGCAGGAGACGCTCGACGCCGACCACTACGGTCTGGAGCGGGTCAAGGATCGCATCCTGGAAT
ACCTGGCGGTACAGAGCCGGGTCAGCAAAATTAAAGGACCGATCCTGTGCCTGGTGGGGCCGCCGGGGGTAGGTAAGACC
TCGCTGGGGCAGTCTATCGCCCGGGCGACCGGACGCCAGTATGTGCGCATGGCGCTGGGCGGGGTGCGCGACGAGGCGGA
GATCCGCGGTCACCGTCGGACCTACATCGGCTCCATGCCGGGTAAACTGATCCAGAAGATGGCCAAGGTAGGGGTGCGCA
ACCCGCTGTTCCTGTTAGATGAAATCGATAAGATGTCCTCTGACATGCGCGGCGATCCGGCCTCGGCGCTGCTGGAGGTC
CTGGACCCGGAGCAGAACGTCGCCTTTAACGATCACTATCTGGAGGTGGACTACGATCTGTCCGACGTGATGTTCGTCGC
CACCTCTAACTCCATGAATATTCCGGCGCCGCTGCTGGACCGCATGGAGGTGATTCGCCTGTCCGGCTATACCGAGGATG
AGAAGCTTAACATTGCCCGCCAGCACCTGCTGCCGAAGCAGATTGAGCGTAATGCGCTGAAGAAAGGCGAGCTAACGGTG
GATGATAGCGCCATCGTTGGGATTATTCGCTACTACACCCGCGAAGCCGGGGTGCGTGCGCTGGAGCGTGAAATCTCCAA
GCTATGTCGCAAGGCGGTGAAACAGCTGCTGCTGGATAAGTCGCTGCGCCATATTGAGATCAACGGCGATAACCTGAAGG
ATTACCTGGGCGTTCAGCGCTTTGACTATGGCCGCGCCGACAGCGAAAACCGCGTGGGGCAGGTCACCGGCCTGGCCTGG
ACCGAGGTCGGCGGCGATCTGCTGACCATTGAAACCGCCTGTGTCCCGGGTAAGGGTAAGCTGACCTATACCGGCTCGCT
GGGCGAAGTGATGCAGGAGTCGATTCAGGCGGCGCTGACCGTGGTGCGCGCGCGCGCCGACAAGCTGGGGATCAACCCGG
ATTTCTACGAGAAGCGCGATATCCACGTGCACGTACCGGAGGGGGCGACCCCGAAAGATGGTCCGAGCGCCGGTATTGCC
ATGTGTACGGCGCTGGTCTCCTGCCTGACCGGTAATCCGGTGCGCGCCGACGTGGCGATGACCGGGGAGATTACGCTGCG
TGGCCAGGTGCTGCCGATCGGCGGGCTGAAGGAGAAGCTGCTGGCGGCCCACCGCGGTGGGATCAAGACCGTGCTGATCC
CGGACGACAACAAACGCGATCTGGAGGAGATGCCGGAGAACGTTCTGCGCGATCTCGACATCCATCCGGTGAAGCGGATC
GACGAGGTTTTGGCCCTGGCGCTGCAGAATTCCCCGTTTGGGATGGACGTGGTGACGGCGAAATAG