Detailed information of regulator


Summary

Regulator ID REG0005 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS01264 experimental (Type i3)
Strain Serratia marcescens strain RM66262
Replicon chromosome
Sequence Protein sequence (247 a.a.); Nucleotide sequence (741 bp)
Description In the wecG mutant strain, in which the Rcs system is activated, Hcp secretion was increased.
Reference
External database links

Locus tag (Gene) RT90_16255 (wecG)
Coordinates (Strand) 92056..92796 (-)
NCBI ID 735005313
GenBank JWLO01000003
Uniprot ID A0A1C3HLJ1_SERMA
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
RT90_01105 (rcsC) ↑ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
Glyco_tran_WecG PF03808.15 7.4e-52 65..231
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-246 MEAKISVPQYELRGFSLWGFRDMAHCMDFLFDGGRVKQGTLVAMNAEKILKAEEDQALHALLDEAEYKYADGISMVRSIRRKYPAADVSRVAGADLWEALMQRAGREGTPVFLVGGKPEVLAETEQKLRSQWNVNLVGSQDGYFKPDQREALFERIRASGAAIVTVAMGSPKQEILMRDCRKVHPQALYMGVGGTYDVFTGHVKRAPKVWQNLGLEWLYRLLSQPSRIGRQLKLLKFVGYYYSGKM


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9952 - -


  Protein sequence of regulator: 247 a.a.    .

>REG0005 JWLO01000003:c92796-92056 [Serratia marcescens]
MEAKISVPQYELRGFSLWGFRDMAHCMDFLFDGGRVKQGTLVAMNAEKILKAEEDQALHALLDEAEYKYADGISMVRSIR
RKYPAADVSRVAGADLWEALMQRAGREGTPVFLVGGKPEVLAETEQKLRSQWNVNLVGSQDGYFKPDQREALFERIRASG
AAIVTVAMGSPKQEILMRDCRKVHPQALYMGVGGTYDVFTGHVKRAPKVWQNLGLEWLYRLLSQPSRIGRQLKLLKFVGY
YYSGKM*

  Nucleotide sequence of regulator: 741 bp    .

>REG0005 JWLO01000003:c92796-92056 [Serratia marcescens]
ATGGAAGCAAAGATTTCGGTGCCGCAGTATGAGCTGCGCGGTTTCAGCCTGTGGGGCTTTCGCGATATGGCGCACTGCAT
GGACTTTTTGTTCGACGGCGGCCGGGTAAAACAGGGCACGCTGGTGGCCATGAACGCGGAAAAGATCCTGAAGGCGGAAG
AGGACCAGGCGCTGCATGCGTTGCTGGATGAGGCGGAGTACAAGTACGCAGACGGCATCAGCATGGTGCGCTCGATTCGC
CGCAAATACCCGGCGGCGGACGTTTCGCGCGTTGCGGGCGCCGATCTGTGGGAAGCCTTGATGCAACGCGCCGGCCGTGA
AGGCACGCCGGTCTTCCTGGTCGGCGGCAAGCCGGAGGTTTTGGCGGAAACCGAGCAAAAGCTGCGCAGCCAGTGGAATG
TCAACCTGGTGGGCAGCCAGGACGGCTACTTCAAACCGGATCAGCGCGAGGCGCTGTTCGAGCGTATTCGTGCCAGCGGC
GCCGCGATCGTGACGGTGGCGATGGGATCGCCGAAGCAGGAGATTCTGATGCGCGACTGCCGCAAGGTGCATCCGCAGGC
GCTGTATATGGGCGTGGGCGGCACCTACGACGTCTTTACCGGCCATGTGAAGCGTGCGCCCAAGGTGTGGCAGAATCTCG
GTCTGGAATGGCTCTACCGCCTGCTCAGCCAACCCAGCCGCATCGGCCGGCAGTTGAAGCTGTTGAAGTTTGTCGGCTAC
TATTACAGCGGCAAGATGTAA