Detailed information of regulator
Summary
| Regulator ID | REG0211  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | Metabolic pathways (map01100); Biosynthesis of secondary metabolites (map01110); Microbial metabolism in diverse environments (map01120); Biosynthesis of amino acids (map01230); Lysine biosynthesis (map00300); Monobactam biosynthesis (map00261) |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (294 a.a.); Nucleotide sequence (882 bp) |
| Description | Putative repressors of esrB as identified by Tn-seq. |
| Reference |
External database links
| Locus tag (Gene) | ETAE_1096 (dapA) |
| Coordinates (Strand) | 1194778..1195659 (+) |
| NCBI ID | 502610962 |
| RefSeq | NC_013508 |
| Uniprot ID | D0ZEY7_EDWTE, A0A0H3DT64_EDWTF |
| KEGG ID | etr:ETAE_1096, etd:ETAF_1023 |
| KEGG pathway (determined by BlastKOALA) | map01100; map01110; map01120; map01230; map00300; map00261 |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| ETAE_0886 (esrB) promoter | ↑ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| DHDPS | PF00701.24 | 9.5e-114 | 2..289 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-293 | MFTGSIVALVTPMDDKGNVDRASLKKLVDYHVASGTSAIVAVGTTGESATLSHDEHVNVVLQTLELADGRIPVIAGAGANATAEAIALTERFNHSGVVGCLSVTPYYNKPTQEGLYQHFRAIASCTDLPQILYNVPSRTGCDMLPETVARLAQIDNIIAIKEATGNLSRVGQIQDLVNDDRFILLSGDDASALDFMRLGGKGVISVTANVAARQMAEMCRLTLAGDFHAARRLNLSLMPLHRDLFIEANPIPVKWATKVLGLIATDTLRLPLTPLSASAHPAVERALQHAGVL |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9528 | - | - |
Protein sequence of regulator: 294 a.a. .
>REG0211 NC_013508:1194778-1195659 [Edwardsiella tarda EIB202]
MFTGSIVALVTPMDDKGNVDRASLKKLVDYHVASGTSAIVAVGTTGESATLSHDEHVNVVLQTLELADGRIPVIAGAGAN
ATAEAIALTERFNHSGVVGCLSVTPYYNKPTQEGLYQHFRAIASCTDLPQILYNVPSRTGCDMLPETVARLAQIDNIIAI
KEATGNLSRVGQIQDLVNDDRFILLSGDDASALDFMRLGGKGVISVTANVAARQMAEMCRLTLAGDFHAARRLNLSLMPL
HRDLFIEANPIPVKWATKVLGLIATDTLRLPLTPLSASAHPAVERALQHAGVL*
MFTGSIVALVTPMDDKGNVDRASLKKLVDYHVASGTSAIVAVGTTGESATLSHDEHVNVVLQTLELADGRIPVIAGAGAN
ATAEAIALTERFNHSGVVGCLSVTPYYNKPTQEGLYQHFRAIASCTDLPQILYNVPSRTGCDMLPETVARLAQIDNIIAI
KEATGNLSRVGQIQDLVNDDRFILLSGDDASALDFMRLGGKGVISVTANVAARQMAEMCRLTLAGDFHAARRLNLSLMPL
HRDLFIEANPIPVKWATKVLGLIATDTLRLPLTPLSASAHPAVERALQHAGVL*
Nucleotide sequence of regulator: 882 bp .
>REG0211 NC_013508:1194778-1195659 [Edwardsiella tarda EIB202]
ATGTTCACGGGAAGTATTGTAGCGCTGGTAACGCCGATGGATGACAAGGGAAATGTCGATCGCGCGAGCCTGAAAAAGTT
GGTCGATTACCATGTCGCCAGCGGGACGTCCGCCATTGTTGCCGTGGGCACCACCGGTGAGTCCGCCACGCTGAGCCATG
ACGAGCATGTCAACGTGGTTTTACAGACGCTGGAGCTGGCCGATGGCCGGATTCCGGTGATCGCCGGGGCGGGCGCTAAC
GCCACCGCCGAGGCCATTGCGCTGACCGAGCGTTTTAATCACAGCGGGGTGGTGGGATGTCTGTCGGTCACGCCGTATTA
TAATAAGCCGACGCAGGAAGGGTTGTATCAGCACTTCCGTGCCATCGCCTCTTGTACCGATCTGCCGCAGATTCTGTATA
ACGTGCCGTCGCGCACCGGTTGCGATATGCTGCCGGAGACCGTGGCGCGTTTGGCGCAGATTGACAATATTATCGCGATT
AAAGAAGCGACCGGGAACTTAAGCCGCGTTGGGCAGATCCAAGATCTGGTCAACGACGATCGCTTTATCCTGCTCAGCGG
TGATGATGCCTCGGCGCTGGACTTTATGCGTCTGGGCGGAAAAGGGGTTATCTCGGTAACCGCGAACGTGGCCGCGCGCC
AGATGGCGGAAATGTGCCGCCTGACGCTGGCCGGGGATTTCCATGCCGCACGCAGGCTAAACCTGAGCCTGATGCCGCTG
CATCGCGATCTGTTTATAGAAGCAAACCCGATACCGGTAAAATGGGCCACCAAGGTATTGGGACTGATAGCGACCGACAC
CCTGCGTCTGCCGCTGACACCGCTGAGCGCCAGTGCGCACCCGGCGGTTGAGCGCGCACTGCAGCATGCCGGTGTGCTGT
AA
ATGTTCACGGGAAGTATTGTAGCGCTGGTAACGCCGATGGATGACAAGGGAAATGTCGATCGCGCGAGCCTGAAAAAGTT
GGTCGATTACCATGTCGCCAGCGGGACGTCCGCCATTGTTGCCGTGGGCACCACCGGTGAGTCCGCCACGCTGAGCCATG
ACGAGCATGTCAACGTGGTTTTACAGACGCTGGAGCTGGCCGATGGCCGGATTCCGGTGATCGCCGGGGCGGGCGCTAAC
GCCACCGCCGAGGCCATTGCGCTGACCGAGCGTTTTAATCACAGCGGGGTGGTGGGATGTCTGTCGGTCACGCCGTATTA
TAATAAGCCGACGCAGGAAGGGTTGTATCAGCACTTCCGTGCCATCGCCTCTTGTACCGATCTGCCGCAGATTCTGTATA
ACGTGCCGTCGCGCACCGGTTGCGATATGCTGCCGGAGACCGTGGCGCGTTTGGCGCAGATTGACAATATTATCGCGATT
AAAGAAGCGACCGGGAACTTAAGCCGCGTTGGGCAGATCCAAGATCTGGTCAACGACGATCGCTTTATCCTGCTCAGCGG
TGATGATGCCTCGGCGCTGGACTTTATGCGTCTGGGCGGAAAAGGGGTTATCTCGGTAACCGCGAACGTGGCCGCGCGCC
AGATGGCGGAAATGTGCCGCCTGACGCTGGCCGGGGATTTCCATGCCGCACGCAGGCTAAACCTGAGCCTGATGCCGCTG
CATCGCGATCTGTTTATAGAAGCAAACCCGATACCGGTAAAATGGGCCACCAAGGTATTGGGACTGATAGCGACCGACAC
CCTGCGTCTGCCGCTGACACCGCTGAGCGCCAGTGCGCACCCGGCGGTTGAGCGCGCACTGCAGCATGCCGGTGTGCTGT
AA