SecReT6, T6SS database

Yersinia

Experimental investigation has been performed.

Bioinformatics investigation has been performed

T6SS ID	Type	Organism	Replicon (Accession)	Location	Function
T6SS00225	i3	Yersinia pseudotuberculosis IP 31758	chromosome (NC_009708)	3850633..3874248	-
T6SS00260	i3	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3905709..3929297	effector translocation
T6SS00017	i3	Yersinia pestis CO92	chromosome (NC_003143)	526127..562682	anti-eukaryotic; virulence
T6SS00258	i3	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1619849..1653371	anti-bacterial

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Regulator ID	Locus tag (Gene)	Related T6SS	Regulator type	Regulatory pathway	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID	Target (Regulation)
REG0185	YpsIP31758_3980 (ompR)	T6SS00225	protein	TCS-RR	Yersinia pseudotuberculosis IP 31758	chromosome (NC_009708)	4465260..4465979 (-)	490527984	T6SS-4 promoter (↓)
REG0186	YpsIP31758_3441 (lptD)	T6SS00225	protein	Unknown	Yersinia pseudotuberculosis IP 31758	chromosome (NC_009708)	3878499..3880841 (+)	499505072	YpsIP31758_3980 (ompR) (↓)
REG0187	YPK_3449 (RelA)	T6SS00260	protein	(p)ppGpp regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3783755..3785989 (-)	488138165	YPK_1551 (RovM) (↓); YPK_1876 (RovA) (↓)
REG0188	YPK_1876 (RovA)	T6SS00260	protein	(p)ppGpp regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	2082384..2082815 (+)	488139747	T6SS-4 promoter region (↓); T6SS-4 promoter region (↓)
REG0189	YPK_4079 (OxyR)	T6SS00260	protein	Global regulator	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	4502978..4503895 (-)	488138270	T6SS-4 promoter region (↓)
REG0190	ypk_3425 (RpoS)	T6SS00260	protein	Global regulator	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3759239..3760237 (-)	499505140	T6SS-4 promoter region (↓)
REG0191	YPK_1551 (RovM)	T6SS00260	protein	(p)ppGpp regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1713682..1714884 (-)	499506038	T6SS-4 promoter region (↓)
REG0192	YPK_3567 (RovC)	T6SS00260	protein	carbon storage regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3929654..3930397 (+)	170025782	YPK_3567 promotor (↓)
REG0193	YPK_3372 (CsrA)	T6SS00260	protein	carbon storage regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3698608..3698793 (-)	169752121	YPK_3567 (RovC) (↑); YPK_3563 transcript (↑)
REG0194	YPK_2462 (HpaR)	T6SS00260	protein	Global regulator	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	2695107..2695574 (+)	169751221	T6SS4 promoter (↓)
REG0195	YPK_RS08345 (YpsR)	T6SS00256	protein	QS regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1837676..1838413 (+)	488140651	T6SS transcripts (↓)
REG0196	YPK_RS03965 (YtbR)	T6SS00256	protein	QS regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	900476..901219 (+)	488140447	T6SS transcripts (↓)
REG0197	YPK_RS08350 (ypsI)	T6SS00256	protein	QS regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1838406..1839050 (-)	501053391	T6SS transcripts (↓)
REG0198	YPK_RS03970 (ytbI)	T6SS00256 ; T6SS00260	protein	QS regulatory pathway	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	901200..901850 (-)	488144695	T6SS transcripts (↓); T6SS4 transcripts and hcp secretion (↓)
REG0199	YPK_RS00840 (OmpR)	T6SS00260	protein	TCS-RR	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	223260..223979 (+)	488137706	T6SS4 promoter (↓)
REG0200	YPK_RS01520 (ZntR)	T6SS00260	protein	Global regulator	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	333471..333896 (+)	488144494	T6SS4 promoter (↓)
REG0366	YPK_RS19410 (Zur)	T6SS00260	protein	Global regulator	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	4251751..4252260 (+)	488143439	T6SS4 transcription (↓)

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Effector ID	Locus tag (Gene)	Classification	Cognate immunity protein	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID
EFF01873	YPK_RS04780	Tde	-	T6SS00258	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1067938..1069470 (+)	499506274
EFF01874	YPK_0954 (Tce1)	Tde	IMU00376	T6SS00258	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1069948..1070205 (+)	488156855
EFF01462	YPK_RS17835	Tie	-	T6SS00260	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3905334..3905687 (-)	169752298
EFF00321	YPK_RS17880	-	-	T6SS00260	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3917120..3919468 (-)	170025773
EFF00322	YPK_RS17905	-	-	T6SS00260	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3925548..3926066 (-)	170025778
EFF76649	YPK_3548 (TssS)	Tie	-	T6SS00260	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3905041..3905187 (-)	-

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Immunity protein ID	Locus tag (Gene)	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Cognate effector
IMU00376	YPK_0955 (Tci1)	T6SS00260	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1070252..1070536 (+)	499506273	EFF01874

Experimental investigation has been performed.

Bioinformatics investigation has been performed

ID	Locus tag (Gene)	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Response to T6SS attack	Known or putative function

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Accessory protein ID	Locus tag (Gene)	Related T6SS	Type	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Related structure protein	Related effector
ACP00014	YPK_0782 (btuB)	T6SS00258	chaperone	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1069948..1070205 (+)	488156855	-	YPK_0954 (Tce1)
ACP00015	YPK_2649 (ompF)	T6SS00258	chaperone	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	2911078..2912160 (+)	501261276	-	YPK_0954 (Tce1)
ACP00016	YPK_2956 (tonB)	T6SS00258	chaperone	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3254339..3255631 (-)	488139530	-	YPK_0954 (Tce1)