Detailed information of regulator
Summary
| Regulator ID | REG0366  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | Global regulator |
| KEGG pathway (determined by BlastKOALA) | Quorum sensing (map02024) |
| Related T6SS | T6SS00260 (Type i3) |
| Strain | Yersinia pseudotuberculosis YPIII |
| Replicon | chromosome |
| Sequence | Protein sequence (170 a.a.); Nucleotide sequence (510 bp) |
| Description | Zur promotes the expression of T6SS4 by directly binding to its promoter. |
| Reference |
External database links
| Locus tag (Gene) | YPK_RS19410 (Zur) |
| Coordinates (Strand) | 4251751..4252260 (+) |
| NCBI ID | 488143439 |
| RefSeq | NC_010465 |
| Uniprot ID | Q66FG6_YERPS |
| KEGG ID | yps:YPTB0371, ypo:BZ17_2199 |
| KEGG pathway (determined by BlastKOALA) | map02024 |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| T6SS4 transcription | ↓ | ATCACAACAGAGAATAGCTATAACCTATAAC The binding sequence was shown the inverted repeat sequences were highlighted in red. |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| FUR | PF01475.21 | 8.3e-13 | 20..138 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-169 | MNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAKPPTVYRALDFLLEQGFIHRVESANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEEALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCEHDHSIVVKKK |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9905 | - | - |
Protein sequence of regulator: 170 a.a. .
>REG0366 NC_010465:4251751-4252260 [Yersinia pseudotuberculosis YPIII]
MNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAKPPTVYRALDFLLEQGFIHRVE
SANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEEALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCEH
DHSIVVKKK*
MNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAKPPTVYRALDFLLEQGFIHRVE
SANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEEALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCEH
DHSIVVKKK*
Nucleotide sequence of regulator: 510 bp .
>REG0366 NC_010465:4251751-4252260 [Yersinia pseudotuberculosis YPIII]
ATGAACCCTATCAATCAGGAAAAGCTGCTCGCACAAGCTGAAAGCCTGTGCCAACAACGAAACGTCCGGCTGACCCCGCA
ACGTCTTGAAGTATTACGTCTAATGGCGCAACAGCCCGGTGCAATTAGCGCTTATGATCTGCTGGATCTACTACGAGTCG
CTGAGCCACAAGCCAAACCGCCTACCGTTTATCGCGCACTGGATTTTTTATTGGAGCAAGGGTTTATTCACCGTGTTGAA
TCAGCCAATAGCTATGTTCTCTGCCACCACTTTGAAGAACCCACGCATACTTCTGCCTTGTTTATCTGTGATCGCTGCAA
GATTGTGACAGAACGCCCTACCGTTGGTATTGAAGAGGCATTGGCACAGTTAGCAAAACAGTCAGGTTTTACACTGCGCC
ATAGCGTGGTGGAAGCACACGGTTTATGTACTGAATGTGGGGTAGTTGAAGCCTGCGAAAGCCACGATGATTGTGAGCAT
GACCACTCCATCGTCGTTAAAAAGAAGTAA
ATGAACCCTATCAATCAGGAAAAGCTGCTCGCACAAGCTGAAAGCCTGTGCCAACAACGAAACGTCCGGCTGACCCCGCA
ACGTCTTGAAGTATTACGTCTAATGGCGCAACAGCCCGGTGCAATTAGCGCTTATGATCTGCTGGATCTACTACGAGTCG
CTGAGCCACAAGCCAAACCGCCTACCGTTTATCGCGCACTGGATTTTTTATTGGAGCAAGGGTTTATTCACCGTGTTGAA
TCAGCCAATAGCTATGTTCTCTGCCACCACTTTGAAGAACCCACGCATACTTCTGCCTTGTTTATCTGTGATCGCTGCAA
GATTGTGACAGAACGCCCTACCGTTGGTATTGAAGAGGCATTGGCACAGTTAGCAAAACAGTCAGGTTTTACACTGCGCC
ATAGCGTGGTGGAAGCACACGGTTTATGTACTGAATGTGGGGTAGTTGAAGCCTGCGAAAGCCACGATGATTGTGAGCAT
GACCACTCCATCGTCGTTAAAAAGAAGTAA