Detailed information NTG0000346

Bioinformatically predicted

Overview

• Name: recA
• Type: Machinery gene
• Locus tag: STU_RS09850
• Genome accession: NC_006448
• Coordinates: 64654..65808 (+)
• Length: 384 a.a.
• NCBI ID: WP_002949056.1
• Uniprot ID: A0AAN1ZW31
• Organism: Streptococcus thermophilus LMG 18311
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 59654..70808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STU_RS09825 (stu0054)	mutL	59654..61597 (+)	1944	WP_011225282.1	DNA mismatch repair endonuclease MutL	-
STU_RS09830 (stu0055)	-	61727..61948 (+)	222	WP_041826940.1	hypothetical protein	-
STU_RS09835 (stu0056)	ruvA	62100..62690 (+)	591	WP_002949053.1	Holliday junction branch migration protein RuvA	-
STU_RS09840 (stu0057)	-	62697..63251 (+)	555	WP_011225284.1	DNA-3-methyladenine glycosylase I	-
STU_RS09845 (stu0059)	cinA	63347..64618 (+)	1272	WP_011225285.1	competence/damage-inducible protein A	Machinery gene
STU_RS09850 (stu0060)	recA	64654..65808 (+)	1155	WP_002949056.1	recombinase RecA	Machinery gene
STU_RS09855 (stu0061)	spx	65985..66383 (+)	399	WP_002949058.1	transcriptional regulator Spx	-

Regulatory network

Positive effect      

Negative effect

Regulator	Target	Regulation
comX	recA	positive effect
comX	ssbA	positive effect
comX	comGE	positive effect
comX	comGB	positive effect
comX	comGD	positive effect
comX	comGF	positive effect
comX	comGG	positive effect
comX	radA	positive effect
comX	comEC	positive effect
comX	comFC	positive effect
comX	comEA	positive effect
comX	comGC	positive effect
comX	cinA	positive effect
comX	coiA	positive effect
comX	comGA	positive effect
comX	comFA	positive effect
comX	dprA	positive effect
clpC	comX	negative effect
comR	comX	positive effect
comR	comS	positive effect
comS	comX	positive effect
comS	comS	positive effect
amiC	comS	positive effect
eeP	comS	positive effect
amiD	comS	positive effect
amiF	comS	positive effect
amiA3	comS	positive effect
amiE	comS	positive effect
clpP	comX	negative effect
mecA	comX	negative effect

Sequence

Protein

• Length: 384 a.a.
• Molecular weight: 41470.03 Da
• Isoelectric Point: 4.7444

>NTDB_id=346 STU_RS09850 WP_002949056.1 64654..65808(+) (recA) [Streptococcus thermophilus LMG 18311]
MAKKTKKTEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQTQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGIMFGNPETTPGGRALKFYASVRLDVRG
NTQIKGTGDKKDQNVGKETKIKVVKNKVAPPFKEAFVEIMYGEGISQTGELVKIASDIGIIQKAGAWFSYNGEKIGQGSE
NAKKYLADHPEIFAEIDHKVRVHYGLVELDEDDVVEDTQVEDTQVEDTSDELILDLDSTIEIEE

Nucleotide

• Length: 1155 bp

>NTDB_id=346 STU_RS09850 WP_002949056.1 64654..65808(+) (recA) [Streptococcus thermophilus LMG 18311]
GTGGCTAAGAAAACAAAGAAAACAGAAGAAATCACAAAGAAGTTTGGTGATGAGCGTCGCAAAGCACTCGACGATGCATT
AAAAAACATTGAAAAAGATTTTGGTAAGGGTGCAGTTATGCGTCTTGGTGAGCGTGCAGAGCAAAAAGTTCAGGTTATGA
GCTCAGGCTCGCTAGCTTTGGATATTGCTCTTGGTGCGGGTGGTTACCCTAAAGGTCGTATTATTGAAATTTACGGACCA
GAATCATCAGGTAAAACAACTGTTGCCCTTCATGCAGTTGCTCAGACTCAAAAAGAAGGTGGCATCGCAGCTTTTATCGA
TGCCGAGCATGCTCTTGACCCTGCGTATGCAGCAGCTCTAGGTGTTAATATCGATGAGCTTCTTTTGTCGCAGCCTGATT
CTGGTGAGCAAGGTCTCGAAATTGCAGGTAAGCTGATTGACTCTGGTGCAGTGGATTTAGTTGTTGTTGACTCAGTTGCG
GCCTTGGTACCACGTGCAGAAATTGATGGAGATATTGGTGACAGTCATGTAGGACTTCAAGCGCGTATGATGAGTCAAGC
CATGCGTAAACTTTCTGCATCTATTAATAAAACAAAAACGATTGCTATCTTTATTAACCAGTTGCGTGAAAAAGTTGGTA
TCATGTTTGGTAACCCAGAGACTACCCCAGGTGGACGTGCTTTAAAATTCTATGCATCAGTACGTCTTGATGTACGTGGT
AATACACAAATTAAAGGAACCGGTGACAAAAAGGACCAAAATGTTGGTAAGGAAACCAAGATTAAGGTTGTTAAAAACAA
AGTTGCTCCACCATTTAAAGAAGCTTTTGTTGAAATTATGTATGGCGAAGGAATTTCACAAACCGGTGAACTTGTAAAAA
TTGCAAGTGATATAGGCATTATTCAGAAAGCCGGAGCTTGGTTCTCATATAATGGGGAGAAAATTGGTCAAGGATCTGAA
AATGCTAAAAAGTATTTAGCAGATCACCCTGAGATTTTTGCAGAAATCGATCATAAAGTACGCGTACACTACGGTCTGGT
TGAGCTAGATGAGGACGATGTTGTTGAAGATACACAAGTTGAAGACACACAAGTTGAAGACACGTCTGATGAACTCATTC
TAGATCTTGATTCAACCATTGAAATCGAAGAATAA

Domains

Predicted by InterproScan.

• recA bacterial DNA recombination protein (RecA) (21-286)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recA	Streptococcus mutans UA159	88.052	100	0.883
recA	Streptococcus pyogenes NZ131	88.021	100	0.88
recA	Streptococcus mitis SK321	85.64	99.74	0.854
recA	Streptococcus mitis NCTC 12261	85.64	99.74	0.854
recA	Streptococcus pneumoniae Rx1	84.715	100	0.852
recA	Streptococcus pneumoniae D39	84.715	100	0.852
recA	Streptococcus pneumoniae R6	84.715	100	0.852
recA	Streptococcus pneumoniae TIGR4	84.715	100	0.852
recA	Lactococcus lactis subsp. cremoris KW2	77.62	91.927	0.714
recA	Latilactobacillus sakei subsp. sakei 23K	67.919	90.104	0.612
recA	Bacillus subtilis subsp. subtilis str. 168	67.781	85.677	0.581
recA	Neisseria gonorrhoeae MS11	59.827	90.104	0.539
recA	Neisseria gonorrhoeae MS11	59.827	90.104	0.539
recA	Neisseria gonorrhoeae strain FA1090	59.827	90.104	0.539
recA	Riemerella anatipestifer ATCC 11845 = DSM 15868	60.177	88.281	0.531
recA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	62.539	84.115	0.526
recA	Glaesserella parasuis strain SC1401	59.412	88.542	0.526
recA	Acinetobacter baylyi ADP1	62.154	84.635	0.526
recA	Acinetobacter baumannii D1279779	62.154	84.635	0.526
recA	Vibrio cholerae O1 biovar El Tor strain E7946	61.231	84.635	0.518
recA	Vibrio cholerae strain A1552	61.231	84.635	0.518
recA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.598	88.802	0.503
recA	Pseudomonas stutzeri DSM 10701	58.462	84.635	0.495
recA	Ralstonia pseudosolanacearum GMI1000	57.576	85.938	0.495
recA	Helicobacter pylori 26695	56.667	85.938	0.487
recA	Helicobacter pylori strain NCTC11637	56.667	85.938	0.487