Detailed information    

experimental Experimentally validated

Overview

Name   recA   Type   Machinery gene
Locus tag   Cj1673c Genome accession   NC_002163
Coordinates   1593765..1594796 (-) Length   343 a.a.
NCBI ID   YP_002345041.1    Uniprot ID   Q0P7V6
Organism   Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819     
Function   homologous recombination   
Homologous recombination

Function

Inactivation of recA also resulted in a loss of natural transformation.


Genomic Context

Location: 1588765..1599796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Cj1666c - 1588944..1589381 (-) 438 YP_002345034.1 periplasmic protein -
  Cj1668c - 1589680..1590096 (-) 417 YP_002345036.1 periplasmic protein -
  Cj1669c - 1590752..1591600 (-) 849 YP_002345037.1 ATP-dependent DNA ligase -
  Cj1670c cgpA 1591600..1592262 (-) 663 YP_002345038.1 glycoprotein CpgA -
  Cj1671c - 1592252..1592455 (-) 204 YP_002345039.1 hypothetical protein -
  Cj1672c eno 1592521..1593765 (-) 1245 YP_002345040.1 enolase -
  Cj1673c recA 1593765..1594796 (-) 1032 YP_002345041.1 recombinase A Machinery gene
  Cj1674 - 1594902..1595762 (+) 861 YP_002345042.1 hypothetical protein -
  Cj1675 fliQ 1595774..1596043 (+) 270 YP_002345043.1 flagellar biosynthesis protein FliQ -
  Cj1676 murB 1596040..1596816 (+) 777 YP_002345044.1 UDP-N-acetylenolpyruvoylglucosamine reductase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37049.27 Da        Isoelectric Point: 4.9784

>NTDB_id=1245 Cj1673c YP_002345041.1 1593765..1594796(-) (recA) [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
MDDNKRKSLDAALKSLDKTFGKGTILRLGDKEVEQIDSIGTGSVGLDLALGIGGVPKGRIIEIYGPESSGKTTLTLHIIA
ECQKAGGVCAFIDAEHALDVKYAKNLGVNTDDLYVSQPDFGEQALEIVETIARSGAVDLIVVDSVAALTPKAEIEGDMGD
QHVGLQARLMSQALRKLTGIVHKMNTTVIFINQIRMKIGAMGYGTPETTTGGNALKFYASVRLDVRKVATLKQNEEPIGN
RVKVKVVKNKVAPPFRQAEFDVMFGEGLSREGELIDYGVKLDIVDKSGAWFSYKDKKLGQGRENSKAFLKENPEIADEIT
KAIQNSMGIEGMISGSEDDEGEE

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1245 Cj1673c YP_002345041.1 1593765..1594796(-) (recA) [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
ATGGATGATAATAAAAGAAAATCTCTAGACGCTGCCCTAAAAAGTTTAGATAAAACCTTTGGAAAAGGCACTATTTTAAG
ACTAGGGGATAAAGAAGTCGAGCAAATCGATAGCATAGGCACAGGTTCAGTTGGGCTTGATCTTGCTTTAGGTATAGGCG
GTGTTCCAAAAGGAAGAATTATAGAAATTTATGGACCTGAAAGTTCAGGTAAAACCACTCTAACTTTACATATTATCGCA
GAATGCCAAAAAGCAGGTGGAGTTTGTGCTTTTATCGATGCAGAACATGCGCTTGATGTAAAATATGCTAAAAATTTGGG
TGTAAATACAGATGATTTGTATGTTTCTCAGCCTGATTTTGGAGAACAAGCCTTAGAAATTGTAGAAACTATAGCAAGAA
GTGGCGCAGTAGATCTTATCGTAGTAGATAGCGTTGCAGCACTTACTCCAAAAGCAGAAATTGAAGGCGATATGGGCGAT
CAACATGTAGGACTTCAAGCAAGACTTATGTCTCAAGCTCTAAGAAAACTTACAGGTATAGTTCATAAAATGAATACCAC
AGTAATTTTTATCAACCAAATTCGTATGAAAATCGGTGCTATGGGTTATGGTACTCCTGAAACCACAACAGGTGGAAATG
CATTAAAATTTTATGCTTCTGTGCGTTTAGATGTTAGAAAAGTAGCAACCTTAAAACAAAACGAAGAACCTATAGGAAAC
CGCGTTAAAGTAAAAGTAGTTAAAAATAAAGTTGCTCCTCCATTCAGACAAGCTGAATTTGATGTGATGTTTGGAGAGGG
TTTAAGCCGTGAAGGTGAATTGATCGATTATGGTGTAAAACTTGATATCGTAGATAAAAGTGGTGCGTGGTTTTCTTATA
AAGATAAAAAACTTGGACAAGGTAGAGAAAATTCAAAAGCTTTCTTAAAAGAAAACCCTGAAATTGCAGATGAAATCACA
AAAGCAATTCAAAATTCTATGGGAATAGAAGGTATGATCAGCGGTAGCGAAGATGACGAAGGAGAAGAATAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(7-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P7V6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Helicobacter pylori 26695

79.268

95.627

0.758
  recA Helicobacter pylori strain NCTC11637

78.963

95.627

0.755
  recA Neisseria gonorrhoeae MS11

65.103

99.417

0.647
  recA Neisseria gonorrhoeae strain FA1090

65.103

99.417

0.647
  recA Neisseria gonorrhoeae MS11

65.103

99.417

0.647
  recA Acinetobacter baylyi ADP1

62.974

100

0.63
  recA Acinetobacter baumannii D1279779

61.808

100

0.618
  recA Glaesserella parasuis strain SC1401

65.031

95.044

0.618
  recA Pseudomonas stutzeri DSM 10701

64.832

95.335

0.618
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

63.855

96.793

0.618
  recA Ralstonia pseudosolanacearum GMI1000

62.974

97.443

0.614
  recA Vibrio cholerae strain A1552

64.506

94.461

0.609
  recA Vibrio cholerae O1 biovar El Tor strain E7946

64.506

94.461

0.609
  recA Bacillus subtilis subsp. subtilis str. 168

63.914

95.335

0.609
  recA Streptococcus pneumoniae Rx1

58.824

99.125

0.583
  recA Streptococcus pneumoniae D39

58.824

99.125

0.583
  recA Streptococcus pneumoniae R6

58.824

99.125

0.583
  recA Streptococcus pneumoniae TIGR4

58.824

99.125

0.583
  recA Streptococcus mitis SK321

57.647

99.125

0.571
  recA Streptococcus mitis NCTC 12261

58.967

95.918

0.566
  recA Streptococcus pyogenes NZ131

58.788

96.21

0.566
  recA Latilactobacillus sakei subsp. sakei 23K

59.021

95.335

0.563
  recA Streptococcus mutans UA159

57.704

96.501

0.557
  recA Lactococcus lactis subsp. cremoris KW2

57.447

95.918

0.551
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

59.177

92.128

0.545

Multiple sequence alignment    



References

[1] Esther J Gaasbeek et al. (2009) Functional characterization of excision repair and RecA-dependent recombinational DNA repair in Campylobacter jejuni. Journal of Bacteriology 191(12):3785-93. [PMID: 19376866]