Detailed information NTG0000335

Bioinformatically predicted

Overview

• Name: comFC
• Type: Machinery gene
• Locus tag: STU_RS11430
• Genome accession: NC_006448
• Coordinates: 356680..357342 (+)
• Length: 220 a.a.
• NCBI ID: WP_002949747.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus LMG 18311
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 351680..362342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STU_RS11400 (stu0363)	-	351998..352708 (+)	711	WP_002947183.1	ABC transporter ATP-binding protein	-
STU_RS19130	-	352844..353504 (+)	661	Protein_319	CBS and ACT domain-containing protein	-
STU_RS11415 (stu0366)	cysK	353671..354597 (-)	927	WP_002947179.1	cysteine synthase A	-
STU_RS11420 (stu0367)	-	354699..355325 (-)	627	WP_011225515.1	YigZ family protein	-
STU_RS11425 (stu0368)	comFA	355380..356699 (+)	1320	WP_011225516.1	DEAD/DEAH box helicase	Machinery gene
STU_RS11430 (stu0369)	comFC	356680..357342 (+)	663	WP_002949747.1	ComF family protein	Machinery gene
STU_RS11435 (stu0370)	hpf	357421..357969 (+)	549	WP_011225518.1	ribosome hibernation-promoting factor, HPF/YfiA family	-

Regulatory network

Positive effect      

Negative effect

Regulator	Target	Regulation
comX	comFC	positive effect
comX	ssbA	positive effect
comX	comGE	positive effect
comX	comGB	positive effect
comX	comGD	positive effect
comX	comGF	positive effect
comX	comGG	positive effect
comX	radA	positive effect
comX	comEC	positive effect
comX	recA	positive effect
comX	comEA	positive effect
comX	comGC	positive effect
comX	cinA	positive effect
comX	coiA	positive effect
comX	comGA	positive effect
comX	comFA	positive effect
comX	dprA	positive effect
clpC	comX	negative effect
comR	comX	positive effect
comR	comS	positive effect
comS	comX	positive effect
comS	comS	positive effect
amiC	comS	positive effect
eeP	comS	positive effect
amiD	comS	positive effect
amiF	comS	positive effect
amiA3	comS	positive effect
amiE	comS	positive effect
clpP	comX	negative effect
mecA	comX	negative effect

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 26037.39 Da
• Isoelectric Point: 8.9833

>NTDB_id=335 STU_RS11430 WP_002949747.1 356680..357342(+) (comFC) [Streptococcus thermophilus LMG 18311]
MKCLLCNEWIEPVAQLSDLIMFKQRREYSCEDCKAQFKKLGKARCSNCYKIIDGNSCFDCKIWAKKGYIPKHFAIYRYEE
NMKEYFSRYKFMGDYCLRKIFQQEIKANLKSFLKKGYILVPVPLSEERLEERGFNQVKGLLEGIPYKNIFEKREIEKQSS
RTREERLSQDNSFSLKKGIELPSKIIIIDDIYTTGSTLYQMVKLLDDLDVKEVLTFSLAR

Nucleotide

• Length: 663 bp

>NTDB_id=335 STU_RS11430 WP_002949747.1 356680..357342(+) (comFC) [Streptococcus thermophilus LMG 18311]
ATGAAGTGTCTACTATGTAATGAATGGATTGAACCAGTAGCTCAATTAAGTGATTTAATTATGTTTAAACAAAGAAGAGA
GTATTCTTGTGAAGATTGTAAAGCTCAATTTAAAAAGCTTGGGAAGGCGAGATGTTCAAATTGTTATAAAATAATAGATG
GAAATAGTTGCTTTGATTGCAAAATTTGGGCGAAAAAAGGCTATATTCCAAAACATTTTGCCATTTATCGTTATGAAGAA
AACATGAAAGAGTACTTTAGTCGCTATAAATTTATGGGAGATTATTGTCTTAGAAAAATATTTCAACAAGAAATTAAAGC
CAATTTAAAGTCTTTTTTAAAGAAAGGTTATATCTTAGTACCTGTCCCCTTGTCGGAAGAACGCCTGGAAGAGAGAGGAT
TCAATCAAGTTAAAGGATTACTAGAGGGAATCCCCTATAAAAACATTTTTGAAAAAAGAGAGATCGAGAAGCAATCCTCG
AGAACACGCGAAGAGCGGTTAAGTCAAGATAATTCTTTCAGTTTGAAAAAAGGTATTGAGCTACCAAGTAAGATCATCAT
AATCGATGATATTTACACAACAGGATCTACCCTGTATCAAATGGTCAAACTATTAGATGATTTAGATGTCAAAGAAGTTT
TGACATTTTCCTTAGCTAGATAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFC/cflB	Streptococcus mitis NCTC 12261	45.045	100	0.455
comFC/cflB	Streptococcus mitis SK321	44.595	100	0.45
comFC/cflB	Streptococcus pneumoniae Rx1	43.694	100	0.441
comFC/cflB	Streptococcus pneumoniae D39	43.694	100	0.441
comFC/cflB	Streptococcus pneumoniae R6	43.694	100	0.441
comFC/cflB	Streptococcus pneumoniae TIGR4	43.694	100	0.441