Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   STU_RS11840 Genome accession   NC_006448
Coordinates   432440..433399 (+) Length   319 a.a.
NCBI ID   WP_041828150.1    Uniprot ID   -
Organism   Streptococcus thermophilus LMG 18311     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 427440..438399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STU_RS11825 (stu0451) metG 427965..429968 (+) 2004 WP_002948122.1 methionine--tRNA ligase -
  STU_RS11830 (stu0452) - 430246..431142 (-) 897 WP_041828147.1 LysR family transcriptional regulator -
  STU_RS11840 (stu0453) coiA 432440..433399 (+) 960 WP_041828150.1 competence protein CoiA Machinery gene
  STU_RS11845 (stu0454) pepF 433410..435215 (+) 1806 WP_011225572.1 oligoendopeptidase F Regulator
  STU_RS11850 (stu0455) - 435398..436105 (+) 708 WP_002946027.1 O-methyltransferase -
  STU_RS11855 (stu0456) - 436167..437282 (+) 1116 WP_011225573.1 peptidyl-prolyl cis-trans isomerase -

Regulatory network

Positive effect      
Negative effect
Regulator Target Regulation
  comX coiA positive effect
  comX ssbA positive effect
  comX comGE positive effect
  comX comGB positive effect
  comX comGD positive effect
  comX comGF positive effect
  comX comGG positive effect
  comX radA positive effect
  comX comEC positive effect
  comX comFC positive effect
  comX recA positive effect
  comX comEA positive effect
  comX comGC positive effect
  comX cinA positive effect
  comX comGA positive effect
  comX comFA positive effect
  comX dprA positive effect
  clpC comX negative effect
  comR comX positive effect
  comR comS positive effect
  comS comX positive effect
  comS comS positive effect
  amiC comS positive effect
  eeP comS positive effect
  amiD comS positive effect
  amiF comS positive effect
  amiA3 comS positive effect
  amiE comS positive effect
  clpP comX negative effect
  mecA comX negative effect

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 38070.01 Da        Isoelectric Point: 9.4171

>NTDB_id=344 STU_RS11840 WP_041828150.1 432440..433399(+) (coiA) [Streptococcus thermophilus LMG 18311]
MLIAKNQKGLLVSALENGLNREETYRCPGCQGIVLLRQGKVICPHFAHKSLQDCQFFSENESAQHLSLKATVYQSLDNHG
ERVCIEKVLPELGQIADLFVGDSLALEVQCSRLSQKRLRERTLAYHQIGYEVRWLLGQELWLGQRLTDLQRDFLYFTTKI
GFHLWELDWKREEIRLKYLIYEDIFGRVYYLTKTWSLIENLMTILRFPYQARKVETYQVTQRKKVSHVIQRELMGKNPRW
MRRQEEAYLKGMNLLSLSDQDFFPQVRFPESKHGFVQIRLSIDGFEKLFMQYYRKRDFSYKQTLCPPNFYAKIVDYRHN

Nucleotide


Download         Length: 960 bp        

>NTDB_id=344 STU_RS11840 WP_041828150.1 432440..433399(+) (coiA) [Streptococcus thermophilus LMG 18311]
ATGTTAATCGCTAAAAATCAGAAAGGGCTCTTAGTTTCGGCTCTTGAAAATGGGTTGAATCGTGAGGAAACTTATAGGTG
CCCTGGCTGTCAAGGAATTGTATTGTTGAGACAGGGAAAGGTGATATGCCCGCATTTTGCCCATAAATCTTTGCAGGATT
GTCAGTTTTTCTCAGAAAATGAATCGGCCCAACATTTATCCCTAAAAGCCACTGTGTATCAATCCCTGGACAATCATGGT
GAAAGAGTTTGTATTGAAAAGGTTCTGCCTGAGTTAGGTCAGATTGCGGATTTATTCGTTGGAGATTCCTTAGCCTTGGA
AGTCCAGTGTTCTCGTTTATCACAGAAACGTTTAAGAGAGCGGACTTTAGCTTACCATCAAATAGGTTACGAGGTACGAT
GGCTTTTGGGGCAAGAACTGTGGTTGGGACAGCGTTTAACAGATCTACAGCGTGATTTTCTTTATTTTACAACTAAGATA
GGTTTCCACCTTTGGGAACTTGATTGGAAGAGGGAAGAGATTAGACTTAAGTATCTCATCTATGAGGATATTTTTGGGAG
AGTTTATTACTTAACTAAGACCTGGTCTTTAATAGAAAATCTCATGACCATATTACGTTTTCCTTATCAGGCCAGAAAGG
TGGAGACTTATCAAGTGACTCAGCGAAAGAAAGTCTCACATGTTATTCAACGGGAATTAATGGGGAAAAATCCAAGATGG
ATGAGAAGACAGGAGGAGGCTTATCTTAAGGGGATGAATTTGTTAAGTTTGTCCGATCAGGATTTTTTTCCACAAGTGCG
GTTTCCTGAGTCTAAGCATGGATTTGTCCAAATTAGATTATCTATTGATGGTTTTGAAAAGCTTTTCATGCAGTATTATC
GAAAAAGGGATTTTTCTTACAAGCAAACCCTGTGCCCTCCCAACTTTTATGCTAAAATAGTAGATTATAGACACAATTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(1-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus pneumoniae TIGR4

45.016

97.492

0.439
  coiA Streptococcus pneumoniae Rx1

45.016

97.492

0.439
  coiA Streptococcus pneumoniae D39

45.016

97.492

0.439
  coiA Streptococcus pneumoniae R6

45.016

97.492

0.439
  coiA Streptococcus mitis NCTC 12261

45.016

97.492

0.439

Multiple sequence alignment