Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbA   Type   Machinery gene
Locus tag   STU_RS18050 Genome accession   NC_006448
Coordinates   1646005..1646397 (-) Length   130 a.a.
NCBI ID   WP_011226610.1    Uniprot ID   A0A3G6K2H6
Organism   Streptococcus thermophilus LMG 18311     
Function   ssDNA binding (predicted from homology)   
DNA processing

Genomic Context

Location: 1641005..1651397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STU_RS18020 (stu1839) dapD 1641308..1642006 (-) 699 WP_002951996.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase -
  STU_RS21035 - 1642092..1642846 (-) 755 Protein_1612 HAD family hydrolase -
  STU_RS18030 (stu1842) - 1642961..1643794 (-) 834 WP_011226608.1 methyltransferase domain-containing protein -
  STU_RS18035 (stu1843) - 1644163..1644330 (+) 168 WP_002945733.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  STU_RS18040 - 1644383..1644646 (+) 264 WP_011681674.1 hypothetical protein -
  STU_RS18045 (stu1844) tadA 1644727..1645245 (-) 519 WP_011226609.1 tRNA adenosine(34) deaminase TadA -
  STU_RS18050 (stu1845) ssbA 1646005..1646397 (-) 393 WP_011226610.1 single-stranded DNA-binding protein Machinery gene
  STU_RS18055 (stu1846) - 1646602..1646829 (-) 228 WP_011226611.1 sulfurtransferase TusA family protein -
  STU_RS18060 (stu1847) - 1646844..1647875 (-) 1032 WP_011226612.1 YeeE/YedE family protein -
  STU_RS18065 (stu1848) ytpR 1648013..1648636 (-) 624 WP_002952017.1 YtpR family tRNA-binding protein -
  STU_RS18070 (stu1849) - 1648646..1648960 (-) 315 WP_011226613.1 thioredoxin family protein -
  STU_RS18075 (stu1850) - 1648957..1649241 (-) 285 WP_002952020.1 DUF4651 domain-containing protein -
  STU_RS18080 (stu1851) pepA 1649341..1650408 (+) 1068 WP_011226615.1 glutamyl aminopeptidase -
  STU_RS18085 (stu1852) proC 1650424..1651194 (+) 771 WP_011226616.1 pyrroline-5-carboxylate reductase -

Regulatory network

Positive effect      
Negative effect
Regulator Target Regulation
  comX ssbA positive effect
  comX comGE positive effect
  comX comGB positive effect
  comX comGD positive effect
  comX comGF positive effect
  comX comGG positive effect
  comX radA positive effect
  comX comEC positive effect
  comX comFC positive effect
  comX recA positive effect
  comX comEA positive effect
  comX comGC positive effect
  comX cinA positive effect
  comX coiA positive effect
  comX comGA positive effect
  comX comFA positive effect
  comX dprA positive effect
  clpC comX negative effect
  comR comX positive effect
  comR comS positive effect
  comS comX positive effect
  comS comS positive effect
  amiC comS positive effect
  eeP comS positive effect
  amiD comS positive effect
  amiF comS positive effect
  amiA3 comS positive effect
  amiE comS positive effect
  clpP comX negative effect
  mecA comX negative effect

Sequence

Protein


Download         Length: 130 a.a.        Molecular weight: 14773.70 Da        Isoelectric Point: 5.9275

>NTDB_id=345 STU_RS18050 WP_011226610.1 1646005..1646397(-) (ssbA) [Streptococcus thermophilus LMG 18311]
MYNKVILIGRLTATPEMVKTASDRSFTRVTVAVNRRYKTQNGEREADFITVVVWGRLAETLASYASKGSLISLDGEIRTR
KYDKDGQTHYVTEVLCSSFQLLESRAQRAVRENNPDNDLADLILEEELPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=345 STU_RS18050 WP_011226610.1 1646005..1646397(-) (ssbA) [Streptococcus thermophilus LMG 18311]
ATGTATAACAAAGTAATTTTAATTGGACGTTTGACAGCAACACCTGAAATGGTTAAGACTGCTAGTGACAGGTCTTTTAC
ACGTGTCACAGTTGCGGTTAATCGTCGCTATAAGACGCAAAATGGTGAGCGTGAGGCTGATTTTATCACAGTAGTGGTTT
GGGGCCGTTTAGCTGAGACATTGGCATCTTATGCTAGCAAGGGAAGTTTAATTTCTCTTGATGGTGAGATTCGCACTCGT
AAGTATGATAAGGATGGTCAAACTCATTACGTTACTGAAGTGCTTTGTTCCTCTTTCCAACTTCTGGAGAGTCGTGCTCA
GCGTGCTGTTAGGGAAAATAATCCTGACAATGACTTGGCTGACCTGATTTTAGAAGAAGAGCTTCCCTTTTAG

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(3-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G6K2H6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Streptococcus mutans UA159

79.389

100

0.8
  ssbB Streptococcus sobrinus strain NIDR 6715-7

76.336

100

0.769
  ssbB/cilA Streptococcus pneumoniae TIGR4

74.809

100

0.754
  ssbB/cilA Streptococcus mitis SK321

74.046

100

0.746
  ssbB/cilA Streptococcus pneumoniae R6

74.046

100

0.746
  ssbB/cilA Streptococcus pneumoniae Rx1

74.046

100

0.746
  ssbB/cilA Streptococcus pneumoniae D39

74.046

100

0.746
  ssbB/cilA Streptococcus mitis NCTC 12261

72.519

100

0.731
  ssbB Lactococcus lactis subsp. cremoris KW2

62.5

86.154

0.538
  ssbA Bacillus subtilis subsp. subtilis str. 168

47.17

81.538

0.385
  ssb Latilactobacillus sakei subsp. sakei 23K

46.226

81.538

0.377

Multiple sequence alignment