SecReT6, T6SS database

Aeromonadales

Experimental investigation has been performed.

Bioinformatics investigation has been performed

T6SS ID	Type	Organism	Replicon (Accession)	Location	Function
T6SS00157	i1	Aeromonas hydrophila subsp. hydrophila ATCC 7966	chromosome (NC_008570)	1984799..2036268	-
T6SS00788	i1	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1017876..1061054	anti-eukaryotic; effector translocation; virulence
T6SS00948	i1	Aeromonas hydrophila NJ-35	chromosome (CP006870)	2935924..2976020	-
T6SS01036	i1	Aeromonas hydrophila J-1	chromosome (NZ_CP006883)	2866359..2898257	-
T6SS01208	i1	Aeromonas veronii strain TH0426	chromosome (NZ_CP012504)	2455395..2478287	anti-eukaryotic
T6SS01258	Unknown	Aeromonas hydrophila ML09-119	chromosome (NC_021290)	1311382..1315165	anti-bacterial
T6SS01259	Unknown	Aeromonas hydrophila ML09-119	chromosome (NC_021290)	2201982..2204826	anti-bacterial
T6SS01225	Unknown	Aeromonas hydrophila BSK10	chromosome (-)	-	-
T6SS01226	Unknown	Aeromonas hydrophila FBS35	chromosome (-)	-	-
T6SS01227	Unknown	Aeromonas hydrophila HA50	chromosome (-)	-	-
T6SS01228	Unknown	Aeromonas hydrophila PEG14	chromosome (-)	-	-
T6SS01229	Unknown	Aeromonas hydrophila L316	chromosome (-)	-	-
T6SS01230	Unknown	Aeromonas hydrophila AH9617	chromosome (-)	-	-
T6SS17503	i1	Aeromonas hydrophila strain NF1	chromosome (NZ_JDWB01000021)	42575..80489	anti-bacterial; anti-eukaryotic

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Regulator ID	Locus tag (Gene)	Related T6SS	Regulator type	Regulatory pathway	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID	Target (Regulation)
REG0254	HMPREF1171_RS04760	T6SS00788	protein	Transcription regulator	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1041366..1042904 (+)	WP_005299999.1	hcp expression (↓)
REG0255	HMPREF1171_RS20340	T6SS00788	protein	QS regulatory pathway	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	4528194..4528817 (-)	WP_005308454.1	ahyR (↓)
REG0256	HMPREF1171_RS20345	T6SS00788	protein	QS regulatory pathway	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	4528880..4529662 (+)	WP_005308457.1	hcp and vgrG2 expression (↓)
REG0353	AHA_1842 (VasH)	T6SS00157	protein	QS regulatory pathway	Aeromonas hydrophila subsp. hydrophila ATCC 7966	chromosome (NC_008570)	2010521..2012059 (+)	117617496	T6SS gene cluster promoter (PAHA1826) (↓)
REG0354	AHA_3923 (rpoN)	T6SS00157	protein	Global regulator	Aeromonas hydrophila subsp. hydrophila ATCC 7966	chromosome (NC_008570)	4350676..4352115 (-)	117618923	T6SS gene cluster promoter (PAHA1826) (↓)

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Effector ID	Locus tag (Gene)	Classification	Cognate immunity protein	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID
EFF00200	AHA_RS05640 (VgrG1)	Tre	-	T6SS00157	Aeromonas hydrophila subsp. hydrophila ATCC 7966	chromosome (NC_008570)	1212752..1215535 (+)	117619461
EFF01871	U876_17730 (Tle1AH)	Tle	IMU00373 ; IMU00374	T6SS00948	Aeromonas hydrophila NJ-35	chromosome (CP006870)	3864039..3865991 (-)	827373601
EFF01888	HMPREF1171_RS04800 (TseP)	Tpe	IMU17302	T6SS00788	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1054604..1055227 (+)	WP_029305891.1
EFF00201	AHA_RS09205 (VgrG2)	-	-	T6SS00157	Aeromonas hydrophila subsp. hydrophila ATCC 7966	chromosome (NC_008570)	1991311..1993542 (+)	117621074
EFF00202	AHA_RS09310 (VgrG3)	-	-	T6SS00157	Aeromonas hydrophila subsp. hydrophila ATCC 7966	chromosome (NC_008570)	2019669..2021714 (+)	117620092
EFF01528	U876_17750 (hcp1)	-	-	T6SS00948	Aeromonas hydrophila NJ-35	chromosome (CP006870)	3869323..3869841 (-)	827373605
EFF01529	U876_17565 (Hcp2)	-	-	T6SS00948	Aeromonas hydrophila NJ-35	chromosome (CP006870)	3836933..3837451 (-)	827373572
EFF18622	HMPREF1171_RS04700 (TseI)	Tde	IMU17301	T6SS00788	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1021791..1026428 (+)	WP_005299972.1
EFF76650	HMPREF1171_RS12055 (tseC)	Tse	IMU00361	T6SS00788	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	2753469..2756654 (-)	WP_005303625.1
EFF76651	BE47_RS0112955 (tseC)	Tse	IMU38224	T6SS17503	Aeromonas hydrophila strain NF1	chromosome (NZ_JDWB01000029)	59956..63138 (-)	WP_029301617.1

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Immunity protein ID	Locus tag (Gene)	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Cognate effector
IMU00361	HMPREF1171_RS12050 (tsiC)	T6SS00788	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	2752679..2753485 (-)	WP_005303621.1	EFF76650
IMU00373	U876_17725 (tli1AH)	T6SS00948	Aeromonas hydrophila NJ-35	chromosome (CP006870)	3863341..3864039 (-)	827373600	EFF01871
IMU00374	U876_17720 (tli2AH)	T6SS00948	Aeromonas hydrophila NJ-35	chromosome (CP006870)	3862649..3863341 (-)	827373599	EFF01871
IMU17301	HMPREF1171_RS04705 (TsiI)	T6SS00788	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1027446..1028828 (+)	WP_005299974.1	EFF18622
IMU17302	HMPREF1171_RS23530	T6SS00788	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1055395..1055883 (+)	WP_154956507.1	EFF01888
IMU38224	BE47_RS23540 (tsiC)	T6SS17503	Aeromonas hydrophila strain NF1	chromosome (NZ_JDWB01000029)	59225..59956 (-)	WP_050490294.1	EFF76651

Experimental investigation has been performed.

Bioinformatics investigation has been performed

ID	Locus tag (Gene)	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Response to T6SS attack	Known or putative function

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Accessory protein ID	Locus tag (Gene)	Related T6SS	Type	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Related structure protein	Related effector
ACP26819	HMPREF1171_RS04695 (TecI)	T6SS00788	chaperone	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1021066..1021794 (+)	WP_005299970.1	HMPREF1171_RS04690	HMPREF1171_RS04700 (TseI)