Detailed information of immunity protein


Summary

Immunity protein ID IMU38224 experimental
Cognate effector EFF76651 experimental
Related T6SS (Type) T6SS17503 experimental (Type i1)
Strain Aeromonas hydrophila strain NF1
Replicon chromosome
Sequence Protein sequence (244 a.a.); Nucleotide sequence (732 bp)
Description In comparison to NF2-lux, a higher survival rate (42%) for NF2-lux-pBR322-tsiC?was observed when mixed with NF1, indicating TsiC provided protection for NF2.
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) BE47_RS23540 (tsiC)
Coordinates (Strand) 59225..59956 (-)
NCBI ID WP_050490294.1
RefSeq NZ_JDWB01000029
Uniprot ID UPI00067C49DB
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-52 MDKVNEVVEAYEQETPFHLLSQGEQQRILDANQKKVREAPTLHEWNIRVETP
Transmembrane helix 53-75 FVWLVISIPVGIMMSIGIWLVYS
Outside 76-79 DNDA
Transmembrane helix 80-99 GWAPIIMGAIVAAFTRYLWL
Inside 100-133 ADKNYHYRLTTEGVIVTYQDAIPEAAYTIVRGLA
Transmembrane helix 134-156 WLGVVVCVMAVAVLGPLALVGAG
Outside 157-243 GMALFAVFFTDFKSEVSEHETMFRKDWPYTLSISNRKKALRFESAPFKVAYSDNLYCKSEDFERVIEMIKNQIRCVDIKNIKGHPMI


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9963 - -


  Protein sequence: 244 a.a.    .

>IMU38224 NZ_JDWB01000029:c59956-59225 [Aeromonas hydrophila]
MDKVNEVVEAYEQETPFHLLSQGEQQRILDANQKKVREAPTLHEWNIRVETPFVWLVISIPVGIMMSIGIWLVYSDNDAG
WAPIIMGAIVAAFTRYLWLADKNYHYRLTTEGVIVTYQDAIPEAAYTIVRGLAWLGVVVCVMAVAVLGPLALVGAGGMAL
FAVFFTDFKSEVSEHETMFRKDWPYTLSISNRKKALRFESAPFKVAYSDNLYCKSEDFERVIEMIKNQIRCVDIKNIKGH
PMI*

  Nucleotide sequence: 732 bp    .

>IMU38224 NZ_JDWB01000029:c59956-59225 [Aeromonas hydrophila]
ATGGATAAGGTAAACGAGGTAGTTGAAGCGTACGAGCAGGAGACCCCTTTTCATCTATTATCGCAGGGAGAACAACAACG
CATTCTCGATGCTAATCAGAAGAAAGTGCGTGAAGCCCCTACGCTACATGAGTGGAATATTAGGGTAGAAACACCTTTTG
TTTGGCTAGTTATTTCAATCCCAGTTGGTATTATGATGTCTATTGGTATATGGCTAGTGTATAGCGATAATGATGCTGGT
TGGGCTCCTATTATCATGGGGGCAATAGTTGCGGCCTTTACTCGTTACTTATGGTTGGCAGATAAAAACTATCATTACCG
GCTCACAACGGAAGGTGTTATCGTCACCTATCAGGATGCTATTCCAGAGGCTGCCTACACTATAGTGCGTGGCTTGGCTT
GGCTTGGTGTGGTGGTTTGTGTGATGGCAGTGGCTGTATTGGGGCCATTAGCCCTGGTTGGTGCAGGTGGCATGGCGCTC
TTTGCGGTGTTTTTCACTGACTTTAAGAGTGAAGTTTCAGAGCATGAAACCATGTTTAGAAAAGACTGGCCCTACACGCT
TTCTATTTCTAATAGGAAAAAGGCACTGAGATTTGAATCCGCCCCCTTTAAAGTCGCATATAGCGACAATTTATATTGTA
AGTCTGAGGATTTTGAACGTGTTATTGAAATGATTAAAAATCAAATCAGGTGTGTCGATATAAAAAATATAAAAGGTCAT
CCAATGATTTGA