Detailed information of effector


Summary

Effector ID EFF01871 experimental
Effector type Tle
Cognate immunity protein IMU00373 experimental; IMU00374 experimental
Related T6SS (Type) T6SS00948 experimental (Type i1)
Strain Aeromonas hydrophila NJ-35
Replicon chromosome
Sequence Protein sequence (651 a.a.); Nucleotide sequence (1953 bp)
Description Tle1AH is a phospholipase effector secreted by T6SS
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) U876_17730 (Tle1AH)
Coordinates (Strand) 3864039..3865991 (-)
NCBI ID 827373601
GenBank CP006870
Uniprot ID UPI000640B960
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DUF2235 PF09994.11 9.4e-21 205..431
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-650 MAISAHCIPCEKNNCWIEIDVRDEQNRSFKGQKATLTDATGTSKTVTLKDGPTLVQGFAVGPVTVKLETQPWLKVAQSREALKEGETSQVPAYTDKLFGHDDVKREHIKVTSGDLCLTDPEQPLPEGHKAGQAQPPRFITKHSYVIEVKGYQLTTLRIGVFFDGTANNTFKHREGKSALETALAQCSPEEQQVLLEQCFEGALPDGLNNSEKNDITNIGKTHELYKPPTKTELNVAVYIEGIGTTQGEGDTSMGLGADKGETSSASRVEEACRTQIVAEVKKRLERILPTIECIHKVEFDVFGFSRGASAARQFVNRIDKKGDHPLVESMAADPDIPLKAGFDWASRDDVRIQFVGLFDTVVSSYLWGKRNVALAPDCAERVVHIVAADEWRYHFDLTRITDDAAGTALAENFTEVIIPGAHSDIGGGYYSRWSLRDPNYASPLITENSVIATFSSNELPHIHPADAQAYRDASAYAKMRAGQGWGKGVVSLASHSDATRLGYLNVRPRSLGPITGSQSGGLRNISVDVVLHRVVEGEYSRIPLHMMVEAARDAGVPFKKWVSQGDNAYRLDSALSYPTVNLAKLDELWVDVAQRRGEVINLARSLPDEVYQKLRLSYLHYSADTGLVNKPNRVGDKEIRKLTGNQKGGY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9844 - -


  Protein sequence: 651 a.a.    .

>EFF01871 CP006870:c3865991-3864039 Type VI Lipase Effector (Tle) [Aeromonas hydrophila NJ-35]
MAISAHCIPCEKNNCWIEIDVRDEQNRSFKGQKATLTDATGTSKTVTLKDGPTLVQGFAVGPVTVKLETQPWLKVAQSRE
ALKEGETSQVPAYTDKLFGHDDVKREHIKVTSGDLCLTDPEQPLPEGHKAGQAQPPRFITKHSYVIEVKGYQLTTLRIGV
FFDGTANNTFKHREGKSALETALAQCSPEEQQVLLEQCFEGALPDGLNNSEKNDITNIGKTHELYKPPTKTELNVAVYIE
GIGTTQGEGDTSMGLGADKGETSSASRVEEACRTQIVAEVKKRLERILPTIECIHKVEFDVFGFSRGASAARQFVNRIDK
KGDHPLVESMAADPDIPLKAGFDWASRDDVRIQFVGLFDTVVSSYLWGKRNVALAPDCAERVVHIVAADEWRYHFDLTRI
TDDAAGTALAENFTEVIIPGAHSDIGGGYYSRWSLRDPNYASPLITENSVIATFSSNELPHIHPADAQAYRDASAYAKMR
AGQGWGKGVVSLASHSDATRLGYLNVRPRSLGPITGSQSGGLRNISVDVVLHRVVEGEYSRIPLHMMVEAARDAGVPFKK
WVSQGDNAYRLDSALSYPTVNLAKLDELWVDVAQRRGEVINLARSLPDEVYQKLRLSYLHYSADTGLVNKPNRVGDKEIR
KLTGNQKGGY*

  Nucleotide sequence: 1953 bp    .

>EFF01871 CP006870:c3865991-3864039 Type VI Lipase Effector (Tle) [Aeromonas hydrophila NJ-35]
ATGGCTATCAGTGCCCACTGCATCCCCTGTGAGAAGAACAACTGCTGGATTGAGATAGACGTTCGCGACGAACAGAACCG
CTCGTTCAAGGGGCAAAAGGCCACCTTGACCGATGCCACTGGCACCAGCAAAACCGTGACTCTGAAAGATGGCCCAACCC
TGGTACAAGGCTTTGCGGTGGGGCCGGTGACCGTCAAGCTGGAGACCCAACCTTGGCTCAAAGTTGCTCAGTCCCGTGAA
GCCCTGAAAGAGGGCGAAACCAGCCAGGTTCCCGCTTATACCGACAAACTCTTCGGGCACGACGATGTAAAGCGCGAACA
CATCAAGGTGACTTCCGGCGACCTTTGTCTCACTGACCCCGAACAGCCGCTACCGGAAGGACATAAAGCCGGGCAGGCCC
AACCGCCGCGCTTTATCACCAAACACTCCTACGTGATTGAGGTGAAGGGCTATCAGCTCACCACTCTGCGTATCGGGGTG
TTCTTTGACGGCACCGCCAACAACACCTTCAAGCACAGGGAAGGGAAAAGTGCATTGGAGACAGCCTTGGCGCAATGCAG
CCCGGAAGAGCAACAGGTATTGCTGGAGCAGTGTTTTGAAGGGGCGTTGCCTGATGGCCTCAATAACAGCGAGAAAAACG
ACATAACAAATATTGGTAAAACCCATGAGCTATATAAACCGCCAACAAAAACTGAGTTGAATGTGGCAGTTTATATCGAG
GGTATAGGCACAACTCAAGGTGAGGGTGATACCAGTATGGGTCTGGGGGCGGATAAGGGAGAGACTTCCAGCGCCTCCCG
TGTCGAAGAGGCTTGTCGTACCCAGATCGTAGCGGAGGTCAAGAAACGACTTGAACGGATATTGCCTACCATCGAGTGCA
TCCATAAGGTCGAATTCGATGTCTTTGGCTTTAGTCGGGGCGCCTCTGCCGCTCGCCAGTTTGTGAACCGTATTGACAAG
AAGGGTGACCACCCTTTGGTAGAGTCCATGGCCGCTGACCCCGATATCCCCTTGAAAGCGGGTTTTGACTGGGCCAGTCG
TGATGATGTGCGGATCCAGTTTGTCGGGCTGTTTGATACCGTGGTCAGCTCCTATCTGTGGGGTAAGCGTAATGTGGCGC
TGGCCCCTGATTGTGCCGAACGAGTGGTGCATATCGTGGCGGCTGACGAGTGGCGCTATCACTTTGACTTGACCCGTATC
ACAGACGATGCCGCAGGCACCGCACTCGCGGAGAATTTTACCGAAGTGATTATTCCCGGCGCCCACTCCGACATCGGTGG
CGGCTATTACAGCCGCTGGAGTTTGCGTGACCCCAATTATGCGTCACCGCTGATCACTGAAAACAGTGTGATCGCAACCT
TCAGCTCCAATGAGTTGCCGCACATCCATCCAGCCGATGCCCAGGCATATCGGGATGCAAGTGCCTATGCAAAAATGCGT
GCTGGACAAGGCTGGGGCAAAGGTGTCGTGTCTCTGGCTAGTCATAGTGACGCCACTCGGCTTGGCTATCTGAATGTGCG
CCCCAGGTCACTGGGTCCGATCACGGGCAGTCAATCTGGGGGGCTTAGAAACATCAGCGTAGATGTGGTACTGCACCGAG
TGGTGGAGGGGGAATATTCACGTATACCGCTGCACATGATGGTGGAAGCGGCGCGGGATGCTGGAGTGCCTTTTAAGAAG
TGGGTATCACAAGGTGACAATGCCTACCGCCTAGATAGTGCGCTCTCGTATCCCACTGTGAACTTAGCCAAACTCGATGA
GCTATGGGTTGATGTGGCCCAACGGCGCGGAGAGGTGATCAACTTGGCTCGTAGCTTACCTGATGAGGTGTACCAAAAGT
TGCGGCTGAGTTATTTGCATTACAGCGCAGATACCGGGCTAGTCAACAAGCCCAATAGGGTTGGTGACAAAGAGATCCGC
AAGCTGACGGGTAATCAAAAGGGAGGTTATTAA