Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01258  |
| T6SS type | Type Unknown |
| Strain | Aeromonas hydrophila ML09-119 |
| Replicon (RefSeq) | chromosome (NC_021290) |
| Location | 1311382..1315165 |
| Function | anti-bacterial |
| Comment | Deletion of the hcp1 or vgrG1 genes in vAh strain ML09-119 affected virulence significantly |
| References | [1] Tekedar HC, Abdelhamed H, Kumru S, Blom J, Karsi A, Lawrence ML. et al (2019) Comparative Genomics of Aeromonas hydrophila Secretion Systems and Mutational Analysis of hcp1 and vgrG1 Genes From T6SS.. Front Microbiol. 2.608333333. [PudMed:30687246] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssD | TssI |
| Number | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| AHML_RS05970 | 1306477..1307496 | + | 1020 | WP_016349826.1 | hybrid-cluster NAD(P)-dependent oxidoreductase | ||
| AHML_RS05975 (galE) | 1307581..1308606 | + | 1026 | WP_016349827.1 | UDP-glucose 4-epimerase GalE | ||
| AHML_RS05980 | 1308782..1309531 | - | 750 | WP_016349828.1 | thioredoxin domain-containing protein | ||
| AHML_RS05990 | 1310381..1311151 | + | 771 | WP_016349829.1 | LuxR family transcriptional regulator | ||
| T6CP015722 | TssD | AHML_RS05995 (hcp1) | 1311382..1311900 | + | 519 | WP_011705044.1 | type VI secretion system effector Hcp1 |
| T6CP015723 | TssI | AHML_RS06000 (tssI) | 1312385..1315165 | + | 2781 | WP_016349830.1 | type VI secretion system tip protein VgrG |
| AHML_RS06005 | 1315162..1315962 | + | 801 | WP_016349831.1 | DUF4123 domain-containing protein | ||
| AHML_RS06010 | 1315962..1317959 | + | 1998 | WP_016349832.1 | DUF2235 domain-containing protein | ||
| AHML_RS06015 | 1317959..1318657 | + | 699 | WP_016349833.1 | DUF2931 family protein | ||
| AHML_RS06020 | 1318785..1319669 | - | 885 | WP_016349834.1 | LysR family transcriptional regulator |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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