SecReT6, T6SS database

Burkholderia cenocepacia

Experimental investigation has been performed.

Bioinformatics investigation has been performed

T6SS ID	Type	Organism	Replicon (Accession)	Location	Function
T6SS01276	i4b	Burkholderia cenocepacia strain K56-2	chromosome (NZ_LAUA01000004)	63074..82939	anti-eukaryotic
T6SS00292	i4b	Burkholderia cenocepacia J2315	chromosome I (NC_011000)	363015..382880	anti-eukaryotic; effector translocation; virulence
T6SS01196	i4b	Burkholderia cenocepacia H111	chromosome (NZ_HG938370)	347990..367838	anti-bacterial
T6SS01197	i2	Burkholderia cenocepacia H111	chromosome (NZ_HG938371)	172983..201438	anti-bacterial
T6SS00126	i4b	Burkholderia cenocepacia AU 1054	chromosome I (NC_008060)	2880426..2919827	anti-bacterial; anti-eukaryotic

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Regulator ID	Locus tag (Gene)	Related T6SS	Regulator type	Regulatory pathway	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID	Target (Regulation)
REG0324	WQ49_05050 (cepR)	T6SS01276	protein	QS regulatory pathway	Burkholderia cenocepacia strain K56-2	chromosome (LAUA01000002)	545988..546707 (-)	815852483	T6SS promotor (P (BCAL0340) ) (↓)
REG0325	WQ49_20245 (cciR)	T6SS01276	protein	QS regulatory pathway	Burkholderia cenocepacia strain K56-2	chromosome (LAUA01000016)	843677..844378 (+)	815850423	Unknown (↑)
REG0326	WQ49_19595 (atsR)	T6SS01276	protein	TCS-RR	Burkholderia cenocepacia strain K56-2	chromosome (LAUA01000016)	710895..712715 (+)	815849700	T6SS transcripts (↑); T6SS expression (↑)
REG0327	WQ49_05060 (cepI)	T6SS01276	protein	QS regulatory pathway	Burkholderia cenocepacia strain K56-2	chromosome (LAUA01000002)	547435..548043 (+)	815852485	T6SS expression (↓)
REG0328	WQ49_20250 (cciI)	T6SS01276	protein	QS regulatory pathway	Burkholderia cenocepacia strain K56-2	chromosome (LAUA01000016)	844665..845255 (+)	815850424	T6SS expression (↓)

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Effector ID	Locus tag (Gene)	Classification	Cognate immunity protein	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID
EFF01517	BCAM1857 (TecA)	DddA	-	-	Burkholderia cenocepacia J2315	chromosome (NC_011001)	2076087..2076566 (+)	206563705
EFF00353	QU43_RS38250	-	-	T6SS00292	Burkholderia cenocepacia J2315	chromosome (NC_011000)	368997..369500 (+)	206558749
EFF01848	I35_RS01730 (hcp)	-	-	T6SS01196	Burkholderia cenocepacia H111	chromosome (NZ_HG938370)	353973..354476 (+)	493523014
EFF01849	WQ49_11820 (hcp)	-	-	T6SS01276	Burkholderia cenocepacia strain K56-2 scf7180000000051	chromosome (NZ_LAUA01000004)	76454..76957 (-)	493523014
EFF76636	BCEN_RS18170 (tecA)	-	-	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008061)	779302..779781 (+)	WP_011547418.1
EFF76637	BCEN_RS13090 (tle1)	Tle	IMU38210	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008060)	2888616..2890877 (-)	WP_011546572.1
EFF76638	BCEN_RS13180 (tne1)	Tde	IMU38211	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008060)	2911927..2916584 (-)	WP_011694122.1
EFF76639	BCEN_RS16675 (tne2)	Tde	IMU38212	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008061)	433352..437836 (+)	WP_011547150.1
EFF76640	BCEN_RS22905 (tpe1)	Tme	IMU38213	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008061)	1873432..1876008 (-)	WP_011548259.1
EFF76641	BCEN_RS06980 (tle2)	Tle	IMU38214	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008060)	1552877..1554958 (-)	WP_011545611.1

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Immunity protein ID	Locus tag (Gene)	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Cognate effector
IMU38210	BCEN_RS13095 (tli1)	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008060)	2890864..2891784 (-)	WP_175810064.1	EFF76637
IMU38211	BCEN_RS33190 (tni1)	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008060)	2911341..2911916 (-)	WP_011546584.1	EFF76638
IMU38212	BCEN_RS33450 (tni2)	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008061)	437845..438333 (+)	WP_011547151.1	EFF76639
IMU38213	BCEN_RS33835 (tpi1)	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008061)	1872451..1872882 (-)	WP_077190848.1	EFF76640
IMU38214	BCEN_RS06975 (tli2)	T6SS00126	Burkholderia cenocepacia AU 1054	chromosome (NC_008060)	1551205..1552767 (-)	WP_011545610.1	EFF76641

Experimental investigation has been performed.

Bioinformatics investigation has been performed

ID	Locus tag (Gene)	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Response to T6SS attack	Known or putative function

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Accessory protein ID	Locus tag (Gene)	Related T6SS	Type	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Related structure protein	Related effector