Detailed information of regulator
|Regulatory pathway (from literatures)||QS regulatory pathway|
|KEGG pathway (determined by BlastKOALA)||Metabolic pathways (map01100); Cysteine and methionine metabolism (map00270); Two-component system (map02020); Quorum sensing (map02024); Biofilm formation - Pseudomonas aeruginosa (map02025)|
|Related T6SS||T6SS01276 (Type i4b)|
|Strain||Burkholderia cenocepacia strain K56-2|
|Sequence||Protein sequence (203 a.a.); Nucleotide sequence (609 bp)|
|Description||T6SS activity was recorded as the ability of the bacteria to induce the formation of characteristic ectopic actin nucleations or ‘pearls’ around infected ANA‐1 macrophages. While few pearls were detected around macrophages infected with WT, no pearls were visible around macrophages infected with ΔcepI and ΔcepIΔcciI thus confirming that T6SS expression is QS regulated.|
External database links
|Locus tag (Gene)||WQ49_05060 (cepI)|
|Coordinates (Strand)||547435..548043 (+)|
|KEGG pathway (determined by BlastKOALA)||map01100; map00270; map02020; map02024; map02025|
|Target||Regulation (↓/↑)||Target sequence|
Pfam domain hit(s) of regulator
|Domain||Pfam ID||E-value||Aligned region|
- Transmembrane helices are predicted using TMHMM 2.0 software.
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
|Prediction||Probability||Cleavage site||Signal peptide sequence|
Protein sequence of regulator: 203 a.a. .
Nucleotide sequence of regulator: 609 bp .