Detailed information of regulator


Summary

Regulator ID REG0325 experimental
Regulator type protein
Regulatory pathway (from literatures) QS regulatory pathway
KEGG pathway (determined by BlastKOALA) Quorum sensing (map02024)
Related T6SS T6SS01276 experimental (Type i4b)
Strain Burkholderia cenocepacia strain K56-2
Replicon chromosome
Sequence Protein sequence (234 a.a.); Nucleotide sequence (702 bp)
Description Transcriptional profiling using a custom B. cenocepacia oligonucleotide microarray results that CciR were determined to negatively regulate gene expression
Reference
External database links

Locus tag (Gene) WQ49_20245 (cciR)
Coordinates (Strand) 843677..844378 (+)
NCBI ID 815850423
GenBank LAUA01000016
Uniprot ID UPI000557B5E5
KEGG ID -
KEGG pathway (determined by BlastKOALA) map02024
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
Unknown ↑ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
Autoind_bind PF03472.17 6.2e-25 13..155
GerE PF00196.21 1.6e-16 171..225
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-233 MATAFLNTVDLSSLLKLFGDVSASLGFPRFAISRVSRRHTGNGRAMAVETLCARYPDHWVAHYAQRDYGPVDPVHRMAFARATPYRWADIRGLNRIEQRVLGEARDAGLTSGVSIPLRETNGDILLVNLASPSPEIKTEVHMRLASSIGALFHQELHRLMKPHRPEPALELSPRQQECLAWVARGKSSWAIASIVGISPHTVDYHIAEAMKILGINSRTAAAVHAVTTGLIHV


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8954 - -


  Protein sequence of regulator: 234 a.a.    .

>REG0325 LAUA01000016:843677-844378 [Burkholderia cenocepacia]
MATAFLNTVDLSSLLKLFGDVSASLGFPRFAISRVSRRHTGNGRAMAVETLCARYPDHWVAHYAQRDYGPVDPVHRMAFA
RATPYRWADIRGLNRIEQRVLGEARDAGLTSGVSIPLRETNGDILLVNLASPSPEIKTEVHMRLASSIGALFHQELHRLM
KPHRPEPALELSPRQQECLAWVARGKSSWAIASIVGISPHTVDYHIAEAMKILGINSRTAAAVHAVTTGLIHV*

  Nucleotide sequence of regulator: 702 bp    .

>REG0325 LAUA01000016:843677-844378 [Burkholderia cenocepacia]
CTGGCCACCGCCTTTCTCAATACCGTGGACCTGTCGTCTTTGCTGAAGTTGTTCGGTGACGTGTCCGCTTCGTTGGGCTT
CCCACGCTTTGCCATCAGCCGAGTCTCTCGAAGACACACGGGAAACGGCCGCGCGATGGCAGTCGAGACGCTTTGCGCAC
GCTATCCGGATCATTGGGTCGCCCATTACGCGCAACGAGACTACGGTCCGGTCGATCCGGTCCATCGGATGGCGTTTGCC
CGTGCCACCCCCTATCGATGGGCCGACATCAGAGGCTTGAATCGCATCGAGCAACGCGTGCTCGGTGAGGCACGCGACGC
GGGATTAACCAGTGGCGTGAGTATCCCGCTTCGCGAGACCAACGGCGACATCCTGCTGGTGAATCTCGCCAGTCCGTCGC
CGGAGATCAAGACAGAAGTCCACATGCGGCTCGCGAGCTCAATTGGCGCGCTCTTTCATCAAGAGCTCCATCGATTGATG
AAGCCCCATCGGCCTGAGCCGGCGCTTGAACTCTCCCCGCGCCAACAAGAGTGCCTCGCGTGGGTTGCCCGGGGTAAATC
GTCATGGGCGATCGCCTCCATTGTTGGCATATCGCCCCATACCGTTGACTACCACATCGCCGAAGCGATGAAGATTTTAG
GCATCAACAGTCGAACCGCGGCAGCTGTGCATGCCGTCACAACCGGCTTGATCCACGTGTAA