Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01197  |
| T6SS type | Type i2 |
| Strain | Burkholderia cenocepacia H111 |
| Replicon (RefSeq) | chromosome (NZ_HG938371) |
| Location | 172983..201438 |
| Function | anti-bacterial |
| Comment | The Burkholderia cenocepacia T6SS1 is functional during growth under standard laboratory conditions. |
| References | [1] Spiewak HL, Shastri S, Zhang L, Schwager S, Eberl L, Vergunst AC, Thomas MS. et al (2019) Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition.. Microbiologyopen. NA. [PudMed:30628184] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| I35_RS17300 | 168135..169493 | - | 1359 | WP_006494519.1 | NAD(P)/FAD-dependent oxidoreductase | ||
| I35_RS17305 | 169594..170547 | + | 954 | WP_006483210.1 | LysR family transcriptional regulator | ||
| I35_RS17310 | 170561..170755 | - | 195 | WP_006483197.1 | hypothetical protein | ||
| I35_RS17315 | 170948..171871 | + | 924 | WP_006494518.1 | AraC family transcriptional regulator | ||
| I35_RS17320 | 172006..172899 | + | 894 | WP_006494517.1 | NAD(P)H-binding protein | ||
| T6CP015189 | TssE | I35_RS17325 (tssE) | 172983..173408 | - | 426 | WP_043204613.1 | type VI secretion system baseplate subunit TssE |
| T6CP015190 | TssH | I35_RS17330 (tssH) | 173424..176147 | - | 2724 | WP_006494515.1 | type VI secretion system ATPase TssH |
| T6CP015191 | TssD | I35_RS17335 | 176283..176768 | - | 486 | WP_006494514.1 | Hcp family type VI secretion system effector |
| I35_RS17340 | 176877..178598 | - | 1722 | WP_043204572.1 | OmpA family protein | ||
| T6CP015192 | TssL | I35_RS17345 | 178595..179326 | - | 732 | WP_043204570.1 | DotU family type IV/VI secretion system protein |
| T6CP015193 | TssK | I35_RS17350 (tssK) | 179323..180675 | - | 1353 | WP_006494511.1 | type VI secretion system baseplate subunit TssK |
| T6CP015194 | TssB | I35_RS17355 (tssB) | 181273..181785 | + | 513 | WP_006494510.1 | type VI secretion system contractile sheath small subunit |
| T6CP015195 | TssC | I35_RS17360 (tssC) | 181859..183391 | + | 1533 | WP_006494509.1 | type VI secretion system contractile sheath large subunit |
| T6CP015196 | TssI | I35_RS17365 (vgrG) | 183473..186142 | + | 2670 | WP_006494508.1 | type VI secretion system tip protein VgrG |
| I35_RS17370 | 186139..188124 | + | 1986 | WP_006494507.1 | phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase family protein | ||
| I35_RS17375 | 188128..189411 | + | 1284 | WP_144417391.1 | sel1 repeat family protein | ||
| I35_RS17380 | 189378..190733 | + | 1356 | WP_043204568.1 | sel1 repeat family protein | ||
| I35_RS17385 | 190961..191209 | + | 249 | WP_006494504.1 | PAAR domain-containing protein | ||
| I35_RS17390 | 191220..192437 | + | 1218 | WP_043204567.1 | hypothetical protein | ||
| T6CP015197 | TssM | I35_RS17395 | 192452..196264 | + | 3813 | WP_043204566.1 | type VI secretion protein VasK |
| T6CP015198 | TssA | I35_RS17400 (tssA) | 196261..197841 | + | 1581 | WP_006494501.1 | type VI secretion system protein TssA |
| T6CP015199 | TssF | I35_RS17405 (tssF) | 197851..199665 | + | 1815 | WP_006494500.1 | type VI secretion system baseplate subunit TssF |
| T6CP015200 | TssF | I35_RS17410 (tssG) | 199662..200771 | + | 1110 | WP_144417392.1 | type VI secretion system baseplate subunit TssG |
| T6CP015201 | TssJ | I35_RS17415 (tssJ) | 200911..201438 | + | 528 | WP_006494498.1 | type VI secretion system lipoprotein TssJ |
| I35_RS17420 | 201593..202798 | - | 1206 | WP_006494497.1 | benzoate/H(+) symporter BenE family transporter | ||
| I35_RS17425 | 202974..203999 | - | 1026 | WP_006494496.1 | fatty acid desaturase | ||
| I35_RS17430 | 204243..205070 | + | 828 | WP_043204565.1 | PhnD/SsuA/transferrin family substrate-binding protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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