Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01197  |
| T6SS type | Type i2 |
| Strain | Burkholderia cenocepacia H111 |
| Replicon (RefSeq) | chromosome (NZ_HG938371) |
| Location | 172983..201438 |
| Function | anti-bacterial |
| Comment | The Burkholderia cenocepacia T6SS1 is functional during growth under standard laboratory conditions. |
| References | [1] Spiewak HL, Shastri S, Zhang L, Schwager S, Eberl L, Vergunst AC, Thomas MS. et al (2019) Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition.. Microbiologyopen. NA. [PudMed:30628184] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| I35_RS17300 | 168135..169493 | - | 1359 | WP_006494519.1 | NAD(P)/FAD-dependent oxidoreductase | ||
| I35_RS17305 | 169594..170547 | + | 954 | WP_006483210.1 | LysR family transcriptional regulator | ||
| I35_RS17310 | 170561..170755 | - | 195 | WP_006483197.1 | hypothetical protein | ||
| I35_RS17315 | 170948..171871 | + | 924 | WP_006494518.1 | AraC family transcriptional regulator | ||
| I35_RS17320 | 172006..172899 | + | 894 | WP_006494517.1 | NAD(P)H-binding protein | ||
| T6CP015189 | TssE | I35_RS17325 (tssE) | 172983..173408 | - | 426 | WP_043204613.1 | type VI secretion system baseplate subunit TssE |
| T6CP015190 | TssH | I35_RS17330 (tssH) | 173424..176147 | - | 2724 | WP_006494515.1 | type VI secretion system ATPase TssH |
| T6CP015191 | TssD | I35_RS17335 | 176283..176768 | - | 486 | WP_006494514.1 | Hcp family type VI secretion system effector |
| I35_RS17340 | 176877..178598 | - | 1722 | WP_043204572.1 | OmpA family protein | ||
| T6CP015192 | TssL | I35_RS17345 | 178595..179326 | - | 732 | WP_043204570.1 | DotU family type IV/VI secretion system protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||