Vibrio parahaemolyticus RIMD 2210633

• Map 2
• T6SS gene clusters 2
• Effectors 5
• Immunity proteins 3
• Recipient susceptibility factors 0
• Regulators 19
• Accessory proteins 0

• NC_004603 (chromosome 1)
• NC_004605 (chromosome 2)

NC_004603 (chromosome 1)
 

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NC_004605 (chromosome 2)
 

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Experimental investigation has been performed.
Bioinformatics investigation has been performed

T6SS ID	Type	Organism	Replicon (Accession)	Location	Function
T6SS00043	i1	Vibrio parahaemolyticus RIMD 2210633	chromosome I (NC_004603)	1486402..1526996	anti-eukaryotic; anti-bacterial; effector translocation; adherence; virulence
T6SS00044	i5	Vibrio parahaemolyticus RIMD 2210633	chromosome II (NC_004605)	1074208..1108114	anti-eukaryotic; effector translocation; adherence

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Regulator ID	Locus tag (Gene)	Related T6SS	Regulator type	Regulatory pathway	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID	Target (Regulation)
REG0100	VP_RS12495 (barA)	T6SS00043 ; T6SS00044	protein	TCS-HK	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2712492..2715290 (+)	491625032	Hcp expression and secretion (↓)
REG0101	VP_RS09470 (UvrY)	T6SS00043 ; T6SS00044	protein	TCS-RR	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2037468..2038112 (-)	491529158	CsrB (↓)
REG0102	VP_RS12395 (CsrA)	T6SS00043 ; T6SS00044	protein	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2688313..2688510 (-)	490550575	Hcp and vgrG expression and secretion (↓)
REG0103	CsrB1	T6SS00043 ; T6SS00044	ncRNA	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2438728..2439035 (+)	-	VP_RS12395 (CsrA) (↑)
REG0104	CsrB2	T6SS00043 ; T6SS00044	ncRNA	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	3215766..3216162 (-)	-	VP_RS12395 (CsrA) (↑)
REG0106	vp2049 (Thymidylate kinase, Tmk)	T6SS00043	protein	Unknown	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2150113..2150745 (-)	28898823	T6SS1 (VgrG1) expression and secretion (↓)
REG0107	VP1028 (TfoY)	T6SS00043	protein	c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1077946..1078536 (-)	28897802	T6SS1 (VgrG1) expression and secretion (↓)
REG0108	vp1391	T6SS00043	protein	Global regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1491226..1492857 (-)	28898165	T6SS1 (VgrG1) expression and secretion (↓)
REG0109	vp1407	T6SS00043	protein	Unknown	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1511565..1512017 (-)	28898181	T6SS1 (VgrG1) expression and secretion (↓)
REG0110	VP1133 (hns)	T6SS00043	protein	Global regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1189718..1190125 (-)	28897907	VP1028 (TfoY) (↑)
REG0111	VP2762 (AphA)	T6SS00043 ; T6SS00044	protein	QS regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2929909..2930448 (+)	28899536	T6SS1 transcript (↑); T6SS2 (VPA1027-1024, VPA1043-1028,VPA1044-1046) transcripts (↑)
REG0112	VP2516 (opaR)	T6SS00043 ; T6SS00044	protein	QS regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2653215..2653829 (+)	28899290	vp1407 (↑); VP1388 promotor (↑); VP1400 promotor (↑); VP1409 promotor (↑); T6SS2 (Hcp2) expression and secretion (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1043-1028 transcript (↓); VPA1044-1046 transcript (↓)
REG0114	VP0820 (ToxR)	T6SS00043	protein	Transcription regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	847892..848770 (-)	28897594	VP1400 promotor (↑); VP1409 promotor (↑)
REG0115	VP0350 (CalR/LeuO)	T6SS00044	protein	Transcription regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	344763..345722 (+)	28897124	VPA1027 (hcp2) promotor (↓); VPA1043 (Fha) promotor (↓); VP1133 (H-NS) (↓)
REG0118	VP2516 (OpaR)	T6SS00043	protein	Global regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2653215..2653829 (+)	28899290	T6SS1 (↓)
REG0119	VP1241 (TfoX)	T6SS00044 ; T6SS00043	protein	QS regulatory pathway; c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1309223..1309810 (+)	28898016	T6SS2 (↓); T6SS1 (↓)
REG0105	CsrB3	T6SS00043 ; T6SS00044	ncRNA	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	plasmid (NC_004605)	171473..171785 (+)	-	VP_RS12395 (CsrA) (↑)
REG0116	VPA1088 (cdpA)	T6SS00043	protein	c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	1147728..1150091 (+)	28900943	VP1028 (TfoY) (↑)
REG0117	VPA0739 (vdcA)	T6SS00043	protein	c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	772439..773809 (+)	28900594	VP1028 (TfoY) (↓)

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Effector ID	Locus tag (Gene)	Classification	Cognate immunity protein	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID
EFF01294	VP_RS06875	Tde	IMU00052	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1522167..1524323 (+)	28898189
EFF01293	VP_RS06745	Tse	IMU00051	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1483454..1485205 (+)	28898162
EFF00060	VP_RS06770	-	-	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1495971..1496489 (+)	28898167
EFF01295	VP_RS21220	Tde	-	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	1341875..1344451 (+)	28901118
EFF00061	VP_RS20100	-	-	T6SS00044	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	1081544..1082023 (-)	28900882

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Immunity protein ID	Locus tag (Gene)	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Cognate effector
IMU00051	VP_RS06750	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1485278..1486405 (+)	28898163	EFF00060
IMU00052	VP_RS06880	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1524323..1524916 (+)	28898190	EFF00060
IMU00275	Vti2	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	-		EFF00061

Experimental investigation has been performed.
Bioinformatics investigation has been performed

ID	Locus tag (Gene)	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Response to T6SS attack	Known or putative function

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Accessory protein ID	Locus tag (Gene)	Related T6SS	Type	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Related structure protein	Related effector