Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   FGL73_RS05035 Genome accession   NZ_CP042408
Coordinates   1090158..1091633 (-) Length   491 a.a.
NCBI ID   WP_146978148.1    Uniprot ID   -
Organism   Lactococcus lactis strain CBA3619     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1085158..1096633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL73_RS05015 (FGL73_05015) murG 1085294..1086367 (-) 1074 WP_003130746.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  FGL73_RS05020 (FGL73_05020) murD 1086578..1087930 (-) 1353 WP_038601518.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  FGL73_RS05025 (FGL73_05025) - 1088261..1088602 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  FGL73_RS05030 (FGL73_05030) - 1088734..1089975 (-) 1242 WP_038601519.1 ammonium transporter -
  FGL73_RS05035 (FGL73_05035) covS 1090158..1091633 (-) 1476 WP_146978148.1 HAMP domain-containing histidine kinase Regulator
  FGL73_RS05040 (FGL73_05040) covR 1091642..1092334 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  FGL73_RS05045 (FGL73_05045) - 1092490..1093020 (-) 531 WP_058205814.1 DUF177 domain-containing protein -
  FGL73_RS05050 (FGL73_05050) - 1093151..1093396 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  FGL73_RS05055 (FGL73_05055) - 1093552..1094016 (-) 465 WP_029344120.1 hypothetical protein -
  FGL73_RS05060 (FGL73_05060) - 1094098..1094460 (-) 363 WP_038601523.1 TIGR02328 family protein -
  FGL73_RS05065 (FGL73_05065) - 1094676..1095518 (-) 843 WP_098393427.1 metallophosphoesterase -
  FGL73_RS05070 (FGL73_05070) - 1095748..1096341 (-) 594 WP_038601525.1 TMEM175 family protein -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56197.27 Da        Isoelectric Point: 5.0483

>NTDB_id=377699 FGL73_RS05035 WP_146978148.1 1090158..1091633(-) (covS) [Lactococcus lactis strain CBA3619]
MKKLFTFNKKKETVKESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTSSMDSVEEVLKKADAPL
NSSNLNTYIEATSKIQKGESEGMSLGSILGTRKAFYIYDLNHKLLYSTNRHSFGFQKQANNEMKEIQGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYFEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDIDHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVNSELALG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=377699 FGL73_RS05035 WP_146978148.1 1090158..1091633(-) (covS) [Lactococcus lactis strain CBA3619]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAAAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACCTTTACGTTATTTGCGACCTTGACTTATCAATTAACGATTAGTTCCT
TCATAAAAGAGGAACAGCGACTATTAACTAGTTCTATGGATAGTGTTGAAGAGGTTTTAAAAAAGGCTGATGCCCCTTTG
AATTCTTCAAATTTGAATACTTATATTGAGGCAACATCGAAGATTCAAAAGGGTGAGTCTGAAGGAATGAGTTTGGGGAG
TATCCTTGGTACTCGAAAGGCCTTCTATATTTATGATTTGAATCATAAATTATTGTACTCAACGAATCGGCATAGTTTTG
GTTTTCAAAAACAAGCTAATAATGAGATGAAGGAAATTCAAGGAGAAAATCCAGGTTACTTAGTTCAAAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTTTTGCTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTATTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCACGTTTACAATGATATGATGTTGAAGATGAAGGCGTATTTTGAACAGCA
AAATCGGTTTGTTTCTGATGTGTCTCATGAATTAAGAACGCCCTTAGCTGTCTTGGATGGACATATCAACTTGCTGAATC
GGTGGGGAAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGGATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGACGATTTTGAAATAGTGCTTGATAACCGACTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCCGCTAAATACTCTCCTGAT
GATCGTAAAGAAATTGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTGTCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTGATCATCTTTTCGAACGTTTCTTCAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACAG
GTTTAGGTTTACCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGAGAAATTGAGGTAAATTCAGAACTAGCTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

97.352

100

0.974

Multiple sequence alignment