Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   HB753_RS09750 Genome accession   NZ_CP050270
Coordinates   1985232..1987187 (+) Length   651 a.a.
NCBI ID   WP_019804939.1    Uniprot ID   -
Organism   Streptococcus mutans strain S4     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1980232..1992187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB753_RS09725 (HB753_09725) - 1980429..1980914 (+) 486 WP_019804942.1 cyclic nucleotide-binding domain-containing protein -
  HB753_RS09730 (HB753_09730) argR 1981411..1981848 (+) 438 WP_002262400.1 arginine repressor -
  HB753_RS09735 (HB753_09735) - 1981845..1982192 (+) 348 WP_019804941.1 YlbF family regulator -
  HB753_RS09740 (HB753_09740) hexA 1982185..1984734 (+) 2550 WP_019804940.1 DNA mismatch repair protein MutS Machinery gene
  HB753_RS09745 (HB753_09745) - 1984729..1985007 (-) 279 Protein_1883 transposase -
  HB753_RS09750 (HB753_09750) hexB 1985232..1987187 (+) 1956 WP_019804939.1 DNA mismatch repair endonuclease MutL Machinery gene
  HB753_RS09755 (HB753_09755) ruvA 1987372..1987965 (+) 594 WP_002262395.1 Holliday junction branch migration protein RuvA Machinery gene
  HB753_RS09760 (HB753_09760) - 1988047..1988607 (+) 561 WP_002271569.1 DNA-3-methyladenine glycosylase I -
  HB753_RS09765 (HB753_09765) cinA 1988756..1990012 (+) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  HB753_RS09770 (HB753_09770) recA 1990052..1991203 (+) 1152 WP_002288707.1 recombinase RecA Machinery gene
  HB753_RS09775 (HB753_09775) spx 1991288..1991686 (+) 399 WP_002262391.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73767.48 Da        Isoelectric Point: 6.4586

>NTDB_id=377696 HB753_RS09750 WP_019804939.1 1985232..1987187(+) (hexB) [Streptococcus mutans strain S4]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVTDNGQGIEQADVIMSLRRHATSK
IKKQTDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIYGTLLIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLINDGRELTKTSGKGDLRQALAGIYGVTTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLCYDKTQNDFFLKETTVSEASSEFTVVDKAVNITDNVSG
HSSVKYAQRQMRTCENKEHPSLTMTNKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMSILNEVGVHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=377696 HB753_RS09750 WP_019804939.1 1985232..1987187(+) (hexB) [Streptococcus mutans strain S4]
ATGTCAAAAATTATTGAACTGCCAGAAGTTTTAGCCAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGACTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGTCATGCAACTAGTAAG
ATTAAAAAACAAACCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATATATGGCACTTTATTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAGCTTGCTCATATTATTGATGTCATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAATGATGGCCGTGAATTAACAAAGACGTCAGGTAAAGGCGATCTGCGTCAAGCTTTAGCGGGTATTTATG
GGGTAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAGGTATCTGGTTATATTAGTTTGCCT
GAATTAACACGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGCGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGTTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTATT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGCATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAACTTCCTCTTAAACAATCAAATCTTTGCTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAATATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTACTATGACAAATAA
GCAACAAAAGCGACAGCTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATCATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGAGCATTTTAAATGAGGTTGGAGTTCACTTAGAAAACT
ATGGAGAGAATACTTTCATTTTGAGAGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGACATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAACTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGAGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(453-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.909

100

0.707

Multiple sequence alignment