Detailed information NTG0377696

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: FGL73_RS03405
• Genome accession: NZ_CP042408
• Coordinates: 724791..725639 (+)
• Length: 282 a.a.
• NCBI ID: WP_146978030.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain CBA3619
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 719791..730639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL73_RS03380 (FGL73_03380)	ilvN	720549..721025 (+)	477	WP_010905839.1	acetolactate synthase small subunit	-
FGL73_RS03385 (FGL73_03385)	ilvC	721070..722092 (+)	1023	WP_038600939.1	ketol-acid reductoisomerase	-
FGL73_RS03390 (FGL73_03390)	ilvA	722148..723398 (+)	1251	WP_146978029.1	threonine ammonia-lyase IlvA	-
FGL73_RS03395 (FGL73_03395)	budA	723514..724224 (+)	711	WP_038600933.1	acetolactate decarboxylase	-
FGL73_RS03400 (FGL73_03400)	-	724265..724645 (+)	381	WP_038600930.1	RidA family protein	-
FGL73_RS03405 (FGL73_03405)	dprA	724791..725639 (+)	849	WP_146978030.1	DNA-processing protein DprA	Machinery gene
FGL73_RS03410 (FGL73_03410)	topA	725901..728045 (+)	2145	WP_146978031.1	type I DNA topoisomerase	-
FGL73_RS03415 (FGL73_03415)	trmFO	728117..729460 (+)	1344	WP_098393836.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
FGL73_RS03420 (FGL73_03420)	xerS	729505..730575 (-)	1071	WP_038600916.1	tyrosine recombinase XerS	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 32132.21 Da
• Isoelectric Point: 9.2427

>NTDB_id=377696 FGL73_RS03405 WP_146978030.1 724791..725639(+) (dprA) [Lactococcus lactis strain CBA3619]
MITNFDLYRWKKAGMTNLEVNKLLKFFHRYDKKISLRQMGQVAQLKSIPNFIEQYKNQDVIKLREEYKIYPSFSLLDEIY
PERLKEIYNPPVLLFYQGDISLLKTPKLAFVGSRQASSQGIKAVQKIVTELNQNFTIVSGLAKGIDTASHLSAIKNKIPT
IAVIGTGLDIFYPLENRKIQEYLAKNQLILSEYPVGEKPLRHHFPERNRIIAGLSHGVVVIEAKLRSGSLITCERALEEG
RDIFAVPGNIADGFSDGCNHLIQQGAKLIYQAQDILEEYLYD

Nucleotide

• Length: 849 bp

>NTDB_id=377696 FGL73_RS03405 WP_146978030.1 724791..725639(+) (dprA) [Lactococcus lactis strain CBA3619]
ATGATAACAAATTTTGATTTATATCGTTGGAAAAAAGCTGGCATGACCAATTTAGAAGTAAATAAACTTTTAAAATTTTT
TCATAGATATGATAAAAAAATAAGTTTAAGACAAATGGGACAAGTAGCACAACTTAAATCTATTCCCAACTTTATTGAAC
AATATAAAAATCAAGACGTAATTAAACTGAGAGAAGAGTATAAAATATACCCATCATTTTCTCTTCTGGATGAAATTTAT
CCCGAAAGGCTCAAAGAAATTTACAATCCACCGGTTCTATTATTTTATCAAGGAGATATAAGTCTCTTAAAAACTCCTAA
ATTAGCTTTTGTTGGTAGTCGACAAGCAAGCTCGCAAGGAATTAAAGCCGTCCAAAAAATTGTGACAGAGTTGAACCAAA
ATTTTACGATTGTCAGCGGACTCGCTAAAGGAATTGATACAGCAAGTCATCTTTCTGCCATTAAAAATAAAATACCTACA
ATTGCAGTTATCGGTACAGGCTTAGATATCTTTTATCCTTTAGAAAATCGAAAAATTCAAGAGTATCTTGCTAAAAACCA
ACTAATTCTATCAGAATATCCAGTCGGAGAAAAGCCCCTTCGCCATCATTTTCCTGAACGTAATCGCATCATTGCGGGAC
TTTCACATGGAGTAGTGGTGATAGAAGCAAAGTTACGAAGCGGTAGTTTAATTACTTGTGAGCGCGCTCTGGAAGAAGGA
AGAGACATTTTCGCTGTACCAGGAAACATAGCAGATGGATTTTCAGATGGCTGTAATCATCTAATTCAACAAGGAGCAAA
ATTAATTTATCAAGCCCAAGATATCTTAGAAGAATATTTGTATGATTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

• DNA recombination-mediator protein A (DNA_processg_A) (76-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	85.816	100	0.858
dprA	Streptococcus mutans UA159	59.712	98.582	0.589
dprA/cilB/dalA	Streptococcus mitis SK321	54.643	99.291	0.543
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae R6	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae D39	53.929	99.291	0.535
dprA	Bacillus subtilis subsp. subtilis str. 168	40.364	97.518	0.394
dprA	Haemophilus influenzae Rd KW20	38.889	95.745	0.372
dprA	Latilactobacillus sakei subsp. sakei 23K	38.148	95.745	0.365