Experimental investigation has been performed.
Bioinformatics investigation has been performed

T6SS ID	Type	Organism	Replicon (Accession)	Location	Function
T6SS00463	i2	Escherichia coli 042	chromosome (NC_017626)	4852875..4885437	effector translocation
T6SS00464	i4b	Escherichia coli 042	chromosome (NC_017626)	4893076..4921378	effector translocation
T6SS00485	i1	Escherichia coli 042	chromosome (NC_017626)	243529..266516	-

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Regulator ID	Locus tag (Gene)	Related T6SS	Regulator type	Regulatory pathway	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID	Target (Regulation)
REG0249	EC042_RS18855 (FIS)	T6SS00464	protein	Transcription regulator	Escherichia coli 042	chromosome (NC_017626)	3772795..3773091 (+)	446385050	EC042_RS26480 (aggR) promoter (↓)
REG0250	EC042_RS06800 (Hns)	T6SS00464	protein	Global regulator	Escherichia coli 042	chromosome (NC_017626)	1376831..1377244 (-)	447210122	EC042_RS26480 (aggR) promoter (↑)
REG0251	EC042_RS03685 (Fur)	T6SS00464	protein	Global regulator	Escherichia coli 042	chromosome (NC_017626)	786918..787364 (-)	446053847	EC042_4532 promoter (↑); EC042_4524 (TssB) promotor (↑)
REG0252	EC042_RS19435 (Dam)	T6SS00464	protein	Global regulator	Escherichia coli 042	chromosome (NC_017626)	3861171..3862007 (-)	446664793	EC042_4532 promoter (↑)
REG0248	EC042_RS26480 (aggR)	T6SS00464	protein	Transcription regulator	Escherichia coli 042	plasmid (NC_017627)	41080..41877 (-)	446692110	EC042_RS26480 (aggR) promoter (↓); EC042_RS26480 (aggR) promoter (↓)

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Effector ID	Locus tag (Gene)	Classification	Cognate immunity protein	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID
EFF01465	EC042_RS24220	Tle	IMU00313	T6SS00931	Escherichia coli 042	chromosome (NC_017626)	4865605..4867287 (+)	284924255
EFF00560	EC042_RS24195	-	-	T6SS00463	Escherichia coli 042	chromosome (NC_017626)	4858680..4859171 (+)	387609950
EFF00561	EC042_4564 (AaiC)	-	-	T6SS00464	Escherichia coli 042	chromosome (NC_017626)	4895043..4895549 (+)	387609980

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Immunity protein ID	Locus tag (Gene)	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Cognate effector
IMU00313	EC042_4535 (Tli1EAEC)	T6SS00463	Escherichia coli 042	chromosome (NC_017626)	4867307..4867984 (+)	446118504	EFF00561

Experimental investigation has been performed.
Bioinformatics investigation has been performed

ID	Locus tag (Gene)	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Response to T6SS attack	Known or putative function

Experimental investigation has been performed.
Bioinformatics investigation has been performed

Accessory protein ID	Locus tag (Gene)	Related T6SS	Type	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Related structure protein	Related effector
ACP00032	EC042_RS24300 (tagA)	T6SS00931	structure affiliated protein	Escherichia coli 042	chromosome (NC_017626)	4884070..4885437 (+)	446122356	TssA	-
ACP00033	EC042_RS24190 (tagL/ompA)	T6SS00931	structure affiliated protein	Escherichia coli 042	chromosome (NC_017626)	4856944..4858674 (+)	446480629	TssL	peptidoglycan
ACP00034	EC042_1244 (mltE)	T6SS00931	structure affiliated protein	Escherichia coli 042	chromosome (NC_017626)	1322321..1322932 (+)	481024453	TssM	-
ACP00035	EC042_RS24190 (sciZ)	T6SS00931	structure affiliated protein	Escherichia coli 042	chromosome (NC_017626)	4856944..4858674 (+)	446480629	SciP	peptidoglycan
ACP00036	EC042_RS21585 (yidC)	T6SS00931	chaperone	Escherichia coli 042	chromosome (NC_017626)	4320019..4321665 (+)	446300403	TssL	-
ACP00037	EC042_RS00085 (dnaK)	T6SS00931	chaperone	Escherichia coli 042	chromosome (NC_017626)	13600..15516 (+)	446438280	TssL	-