Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00463  |
| T6SS type | Type i2 |
| Strain | Escherichia coli 042 |
| Replicon (RefSeq) | chromosome (NC_017626) |
| Location | 4852875..4885437 |
| Function | effector translocation |
| Comment | - |
| References | [1] Morin N et al (2013) Characterization of the AggR regulon in enteroaggregative Escherichia coli. Infect Immun. 81(1):122-32. [PudMed:23090962] [2] Zoued A et al (2013) TssK is a trimeric cytoplasmic protein interacting with components of both phage-like and membrane anchoring complexes of the Type VI secretion system. J Biol Chem. 288(38):27031-41. [PudMed:23921384] [3] Durand E et al (2012) Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems. J Biol Chem. 287(17):14157-68. [PudMed:22371492] [4] Dudley EG et al (2006) Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coli. Mol Microbiol. 61(5):1267-82. [PudMed:16925558] [5] Felisberto-Rodrigues C et al (2011) Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar. PLoS Pathog. 7(11):e1002386. [PudMed:22102820] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| EC042_RS24130 (hha) | 4848505..4848717 | + | 213 | WP_000453331.1 | hemolysin expression modulator Hha | ||
| EC042_RS24135 | 4849334..4849903 | + | 570 | WP_000220727.1 | inovirus Gp2 family protein | ||
| EC042_RS30730 | 4849941..4850099 | + | 159 | WP_000493525.1 | hypothetical protein | ||
| EC042_RS24140 | 4850071..4850454 | + | 384 | WP_000271022.1 | hypothetical protein | ||
| EC042_RS24145 | 4850444..4850863 | + | 420 | WP_001387059.1 | hypothetical protein | ||
| EC042_RS24150 | 4850869..4851051 | + | 183 | WP_001216313.1 | hypothetical protein | ||
| EC042_RS24155 | 4851172..4851795 | + | 624 | WP_001260266.1 | hypothetical protein | ||
| EC042_RS24160 | 4851891..4852124 | + | 234 | WP_000124181.1 | hypothetical protein | ||
| EC042_RS24165 | 4852177..4852368 | - | 192 | WP_001287796.1 | DUF4222 domain-containing protein | ||
| T6CP005160 | TssB | EC042_RS24170 (tssB) | 4852875..4853372 | + | 498 | WP_000098939.1 | type VI secretion system contractile sheath small subunit |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF00560 | EC042_RS24195 | - | - | Escherichia coli 042 | chromosome (NC_017626) | 4858680..4859171 (+) | 387609950 |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00313 | EC042_4535 (Tli1EAEC) | EFF01465 | Escherichia coli 042 | chromosome (NC_017626) | 4867307..4867984 (+) | 446118504 |
Showing 1 to 1 of 1 rows
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||