Detailed information of effector
Summary
| Effector ID | EFF00561  |
| Effector type | - |
| Cognate immunity protein | - |
| Related T6SS (Type) | T6SS00464 (Type i4b) |
| Strain | Escherichia coli 042 |
| Replicon | chromosome |
| Sequence | Protein sequence (169 a.a.); Nucleotide sequence (507 bp) |
| Description | - |
| Reference | [1] Dudley EG, Thomson NR, Parkhill J, et al. Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coli. Mol Microbiol. 2006 Sep;61(5):1267-82. PMID: 16925558 [2] Dudley EG, Thomson NR, Parkhill J, et al. Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coli. Mol Microbiol. 2006 Sep;61(5):1267-82. PMID: 16925558 |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | EC042_4564 (AaiC) |
| Coordinates (Strand) | 4895043..4895549 (+) |
| NCBI ID | 387609980 |
| RefSeq | NC_017626 |
| Uniprot ID | UPI0001887CE4 |
| KEGG ID | - |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-168 | MVGVMSNSSALSREFVKIEIGGKVIKGNSKVENSGDYFDGHCPQAFHAFSGIDGTVFDLINLKLRVTKHIQDLLENFFKRGEKEVKIEILRRESTKSGSAYSSFKVVYQGCRMHNMLLAHDNDSNLILELSFTPEESVSIEMNIPSDDGKSTEKLGPMTYNLYKEALV |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9250 | - | - |
Protein sequence: 169 a.a. .
>EFF00561 NC_017626:4895043-4895549 (Unknown) [Escherichia coli 042]
MVGVMSNSSALSREFVKIEIGGKVIKGNSKVENSGDYFDGHCPQAFHAFSGIDGTVFDLINLKLRVTKHIQDLLENFFKR
GEKEVKIEILRRESTKSGSAYSSFKVVYQGCRMHNMLLAHDNDSNLILELSFTPEESVSIEMNIPSDDGKSTEKLGPMTY
NLYKEALV*
MVGVMSNSSALSREFVKIEIGGKVIKGNSKVENSGDYFDGHCPQAFHAFSGIDGTVFDLINLKLRVTKHIQDLLENFFKR
GEKEVKIEILRRESTKSGSAYSSFKVVYQGCRMHNMLLAHDNDSNLILELSFTPEESVSIEMNIPSDDGKSTEKLGPMTY
NLYKEALV*
Nucleotide sequence: 507 bp .
>EFF00561 NC_017626:4895043-4895549 (Unknown) [Escherichia coli 042]
ATGGTCGGAGTTATGAGTAATTCTTCTGCTCTTAGCAGGGAGTTTGTCAAAATAGAGATAGGTGGAAAAGTTATAAAGGG
AAATTCAAAAGTTGAAAACAGTGGTGACTACTTTGATGGACATTGTCCTCAGGCATTTCACGCTTTTTCAGGAATTGACG
GTACTGTTTTTGATTTAATTAATTTGAAGCTTAGGGTTACTAAACACATACAAGACCTTCTGGAGAACTTTTTTAAGAGA
GGTGAAAAAGAAGTTAAAATAGAAATTTTACGTAGGGAATCAACTAAATCAGGTAGTGCATACTCATCATTTAAGGTTGT
TTATCAGGGGTGTCGTATGCATAATATGTTGTTGGCTCATGATAATGATTCAAATCTCATTCTGGAATTGTCGTTTACCC
CAGAAGAGAGTGTCTCAATTGAGATGAATATTCCGTCAGATGATGGAAAAAGTACGGAGAAATTGGGACCAATGACGTAC
AACTTATATAAAGAGGCTCTTGTATAA
ATGGTCGGAGTTATGAGTAATTCTTCTGCTCTTAGCAGGGAGTTTGTCAAAATAGAGATAGGTGGAAAAGTTATAAAGGG
AAATTCAAAAGTTGAAAACAGTGGTGACTACTTTGATGGACATTGTCCTCAGGCATTTCACGCTTTTTCAGGAATTGACG
GTACTGTTTTTGATTTAATTAATTTGAAGCTTAGGGTTACTAAACACATACAAGACCTTCTGGAGAACTTTTTTAAGAGA
GGTGAAAAAGAAGTTAAAATAGAAATTTTACGTAGGGAATCAACTAAATCAGGTAGTGCATACTCATCATTTAAGGTTGT
TTATCAGGGGTGTCGTATGCATAATATGTTGTTGGCTCATGATAATGATTCAAATCTCATTCTGGAATTGTCGTTTACCC
CAGAAGAGAGTGTCTCAATTGAGATGAATATTCCGTCAGATGATGGAAAAAGTACGGAGAAATTGGGACCAATGACGTAC
AACTTATATAAAGAGGCTCTTGTATAA