Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00485  |
| T6SS type | Type i1 |
| Strain | Escherichia coli 042 |
| Replicon (RefSeq) | chromosome (NC_017626) |
| Location | 243529..266516 |
| Function | - |
| Comment | - |
| References | [1] Chaudhuri RR et al (2010) Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One. 5(1):e8801. [PudMed:20098708] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| EC042_RS01110 (gloB) | 239097..239852 | - | 756 | WP_001052736.1 | hydroxyacylglutathione hydrolase | ||
| EC042_RS01115 (yafS) | 239886..240608 | + | 723 | WP_001295200.1 | class I SAM-dependent methyltransferase | ||
| EC042_RS01120 (rnhA) | 240605..241072 | - | 468 | WP_000917883.1 | ribonuclease HI | ||
| EC042_RS01125 (dnaQ) | 241137..241868 | + | 732 | WP_024165575.1 | DNA polymerase III subunit epsilon | ||
| EC042_RS01135 | 242404..243189 | + | 786 | WP_001086160.1 | hypothetical protein | ||
| T6CP009057 | TssD | EC042_RS01140 | 243529..244008 | - | 480 | WP_000013179.1 | Hcp family type VI secretion system effector |
| T6CP009058 | TssA | EC042_RS01145 | 244026..245384 | - | 1359 | WP_000073803.1 | type VI secretion system ImpA and VasL domain-containing protein |
| T6CP005150 | TssM | EC042_RS01150 (tssM) | 245395..248832 | - | 3438 | WP_122986661.1 | type VI secretion system membrane subunit TssM |
| T6CP009059 | TssA | EC042_RS01155 (tssA) | 248942..250384 | - | 1443 | WP_001306815.1 | type VI secretion system protein TssA |
| EC042_RS01160 (tagO) | 250389..251132 | - | 744 | WP_000088844.1 | type VI secretion system-associated protein TagO | ||
| T6CP005151 | TssH | EC042_RS01165 (tssH) | 251129..253861 | - | 2733 | WP_000614302.1 | type VI secretion system ATPase TssH |
| T6CP005152 | TssL | EC042_RS01170 (icmH) | 253871..254644 | - | 774 | WP_001280269.1 | type IVB secretion system protein IcmH/DotU |
| T6CP005153 | TssK | EC042_RS01175 (tssK) | 254649..255995 | - | 1347 | WP_000224513.1 | type VI secretion system baseplate subunit TssK |
| T6CP005154 | TssJ | EC042_RS01180 (tssJ) | 255998..256522 | - | 525 | WP_001013424.1 | type VI secretion system lipoprotein TssJ |
| T6CP011361 | FHA | EC042_RS01185 (tagH) | 256519..257811 | - | 1293 | WP_000433571.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP005155 | TssG | EC042_RS01190 (tssG) | 257816..258865 | - | 1050 | WP_000896719.1 | type VI secretion system baseplate subunit TssG |
| T6CP005156 | TssF | EC042_RS01195 (tssF) | 258829..260670 | - | 1842 | WP_000863395.1 | type VI secretion system baseplate subunit TssF |
| T6CP009060 | TssE | EC042_RS01200 (tssE) | 260676..261101 | - | 426 | WP_001189669.1 | type VI secretion system baseplate subunit TssE |
| T6CP005157 | TssC | EC042_RS01205 (tssC) | 261106..262590 | - | 1485 | WP_000111580.1 | type VI secretion system contractile sheath large subunit |
| T6CP005158 | TssB | EC042_RS01210 (tssB) | 262613..263116 | - | 504 | WP_000041478.1 | type VI secretion system contractile sheath small subunit |
| T6CP009061 | TssD | EC042_RS01215 | 263819..264337 | + | 519 | WP_001142963.1 | Hcp family type VI secretion system effector |
| T6CP005159 | TssI | EC042_RS01225 (tssI) | 264558..266516 | + | 1959 | WP_001306807.1 | type VI secretion system tip protein VgrG |
| EC042_RS01230 | 266516..267355 | + | 840 | WP_000446997.1 | DUF4123 domain-containing protein | ||
| EC042_RS01235 | 267377..268948 | + | 1572 | WP_001306805.1 | hypothetical protein | ||
| EC042_RS01240 | 269063..270025 | + | 963 | WP_000536467.1 | hypothetical protein | ||
| EC042_RS01245 | 270338..271261 | + | 924 | pseudogene | ISAs1 family transposase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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