SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP011361
Component protein type	FHA
T6SS ID (Type)	T6SS00485 (Type i1)
Strain	Escherichia coli 042
Replicon	chromosome
Sequence	Protein sequence (431 a.a.); Nucleotide sequence (1293 bp)
Reference	[1] Chaudhuri RR, Sebaihia M, Hobman JL, et al. Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One. 2010 Jan 20;5(1):e8801. doi: 10.1371/journal.pone.0008801. PMID: 20098708

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	EC042_RS01185
Coordinate (Strand)	256519..257811 (-)
NCBI ID	WP_000433571.1
RefSeq	NC_017626
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-430	MEPLMAEEKQQSRQASLTLQVMNGNELESGRAAKCLFSENGGDIGHTPECHWQVQDRAGSIAARACTVIRHDGAYCLRCLTPGLMINLAPVSSDALIRLRQGDEIQLGALALKVFLHDGVAVTYDERMATPETIVMNRDSLADTLLTTEGQPAYPGMPFQHQLAPTVAHGFSSDPLQALQTESLMVADDPIAPRVSRPVAPASDLTGANGINTPFMDLPPGNARHEDGDEFSAMAQYHLAVTPLLRGMECPLTLHNSQDADEFLEEAGRALQAAIKGLLSLQQQQNSLSDKHLRPLEDNPLRLDMDYPTALNVMFAEGKSPVHLAAPAAIAESLRNIRHHEEANRAAIVEALRVMLDAFSPGNLMRRFAQYRRSHELRQKMDNAWAWQMYSNYYDELASSRQQGFEMLFNEVYAQVYDRVLREKQREPEA

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9613	-	-

Protein sequence: 431 a.a.

						>T6CP011361 NC_017626:c257811-256519 [Escherichia coli 042] [FHA]
MEPLMAEEKQQSRQASLTLQVMNGNELESGRAAKCLFSENGGDIGHTPECHWQVQDRAGSIAARACTVIRHDGAYCLRCL
TPGLMINLAPVSSDALIRLRQGDEIQLGALALKVFLHDGVAVTYDERMATPETIVMNRDSLADTLLTTEGQPAYPGMPFQ
HQLAPTVAHGFSSDPLQALQTESLMVADDPIAPRVSRPVAPASDLTGANGINTPFMDLPPGNARHEDGDEFSAMAQYHLA
VTPLLRGMECPLTLHNSQDADEFLEEAGRALQAAIKGLLSLQQQQNSLSDKHLRPLEDNPLRLDMDYPTALNVMFAEGKS
PVHLAAPAAIAESLRNIRHHEEANRAAIVEALRVMLDAFSPGNLMRRFAQYRRSHELRQKMDNAWAWQMYSNYYDELASS
RQQGFEMLFNEVYAQVYDRVLREKQREPEA*					

Nucleotide sequence: 1293 bp

						>T6CP011361 NC_017626:c257811-256519 [Escherichia coli 042] [FHA]
ATGGAACCACTTATGGCTGAGGAAAAACAGCAATCCCGCCAGGCCTCACTGACTTTACAGGTGATGAATGGCAACGAACT
GGAAAGCGGACGCGCCGCAAAATGCCTGTTCAGCGAAAACGGCGGTGATATTGGCCATACGCCGGAATGTCACTGGCAGG
TACAGGACCGGGCGGGAAGCATTGCTGCGCGTGCCTGTACCGTTATCCGGCACGACGGAGCCTATTGCCTGCGGTGCCTG
ACGCCGGGACTGATGATTAATCTGGCCCCGGTCTCTTCCGATGCGCTCATCCGCCTGCGCCAGGGGGATGAGATCCAGCT
CGGCGCACTGGCGCTGAAAGTGTTTCTGCATGACGGTGTAGCTGTTACCTATGACGAGCGGATGGCGACCCCGGAAACGA
TTGTAATGAACCGCGACAGTCTGGCGGACACCCTGTTGACCACCGAGGGACAACCGGCGTATCCGGGAATGCCGTTCCAG
CATCAGCTTGCCCCCACGGTTGCGCACGGTTTTTCCAGCGATCCGCTCCAGGCACTCCAGACGGAAAGCCTGATGGTGGC
AGATGATCCGATCGCCCCACGCGTTTCCCGGCCCGTTGCCCCCGCCTCCGATCTGACAGGTGCAAACGGGATCAACACGC
CGTTTATGGATCTGCCGCCCGGCAATGCCCGTCATGAGGACGGCGATGAATTTTCTGCCATGGCGCAGTACCACCTGGCC
GTAACCCCGCTGCTGCGCGGTATGGAGTGTCCGCTGACGCTGCACAATTCTCAGGATGCGGATGAGTTTCTCGAAGAGGC
CGGACGGGCGTTGCAGGCCGCCATTAAGGGATTGCTGAGTCTGCAACAACAACAGAACAGCCTGTCGGATAAACACCTGC
GTCCACTGGAAGACAACCCGTTGCGCCTTGATATGGACTATCCCACCGCGCTGAACGTCATGTTCGCCGAGGGTAAAAGC
CCGGTACATCTCGCCGCACCTGCGGCCATCGCCGAAAGCCTGCGCAACATCCGGCATCATGAAGAGGCCAACCGGGCGGC
GATTGTGGAAGCGTTGCGTGTCATGCTGGACGCCTTCTCGCCGGGCAACCTGATGCGCCGCTTTGCGCAATACCGCCGCA
GCCATGAGCTGCGCCAGAAAATGGACAACGCCTGGGCATGGCAGATGTACAGCAACTATTACGATGAACTGGCCTCCAGC
CGACAGCAGGGATTTGAAATGCTGTTCAATGAAGTTTATGCCCAGGTCTATGACCGGGTGCTGCGCGAAAAACAGCGGGA
GCCGGAAGCATGA					