Detailed information    

insolico Bioinformatically predicted

Overview


Name   comP   Type   Machinery gene
Locus tag   GWG10_RS23285 Genome accession   NZ_CP047983
Coordinates   3854302..3854394 (-) Length   30 a.a.
NCBI ID   WP_180911214.1    Uniprot ID   -
Organism   Aeromonas caviae strain 1605-27183     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 3818216..3879303 3854302..3854394 within 0
IScluster/Tn 3846341..3854267 3854302..3854394 flank 35


Gene organization within MGE regions


Location: 3818216..3879303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWG10_RS17760 (GWG10_17775) - 3818216..3819058 (+) 843 WP_180911193.1 lytic transglycosylase domain-containing protein -
  GWG10_RS17765 (GWG10_17780) - 3819629..3819913 (-) 285 WP_180911194.1 DUF2845 domain-containing protein -
  GWG10_RS17770 (GWG10_17785) - 3819985..3820209 (-) 225 WP_180911195.1 hypothetical protein -
  GWG10_RS17775 (GWG10_17790) - 3820206..3822155 (-) 1950 WP_180911196.1 hypothetical protein -
  GWG10_RS17780 (GWG10_17795) - 3822183..3822587 (-) 405 WP_180911197.1 hypothetical protein -
  GWG10_RS23010 - 3822610..3823761 (-) 1152 WP_235687571.1 LamG domain-containing protein -
  GWG10_RS17790 (GWG10_17805) - 3823765..3824937 (-) 1173 WP_180911198.1 hypothetical protein -
  GWG10_RS17795 (GWG10_17810) - 3825053..3828673 (-) 3621 WP_180911199.1 curculin (mannose-binding) lectin protein -
  GWG10_RS17800 (GWG10_17815) - 3829053..3832631 (-) 3579 WP_180911200.1 tape measure protein -
  GWG10_RS17805 (GWG10_17820) - 3832731..3833090 (+) 360 WP_042881735.1 hypothetical protein -
  GWG10_RS17810 (GWG10_17825) - 3833133..3833882 (-) 750 WP_042881737.1 hypothetical protein -
  GWG10_RS17815 (GWG10_17830) - 3833922..3834344 (-) 423 WP_104451772.1 hypothetical protein -
  GWG10_RS17820 (GWG10_17835) - 3834341..3834898 (-) 558 WP_180911201.1 phage tail protein -
  GWG10_RS17825 (GWG10_17840) - 3835055..3836485 (+) 1431 WP_103859375.1 IS4-like element IS50R family transposase -
  GWG10_RS17830 (GWG10_17845) - 3836988..3837299 (-) 312 WP_042016765.1 head-tail connector protein -
  GWG10_RS17835 (GWG10_17850) - 3837302..3837490 (-) 189 WP_180898738.1 hypothetical protein -
  GWG10_RS17840 (GWG10_17855) - 3837557..3838846 (-) 1290 WP_180911202.1 phage major capsid protein -
  GWG10_RS17845 (GWG10_17860) - 3838915..3839850 (-) 936 WP_180911203.1 S49 family peptidase -
  GWG10_RS17850 (GWG10_17865) - 3839838..3841091 (-) 1254 WP_180911204.1 phage portal protein -
  GWG10_RS17855 (GWG10_17870) - 3841091..3841279 (-) 189 WP_113069727.1 hypothetical protein -
  GWG10_RS17860 (GWG10_17875) - 3841273..3842994 (-) 1722 WP_180911205.1 terminase large subunit -
  GWG10_RS17865 (GWG10_17880) - 3843004..3843489 (-) 486 WP_104451780.1 phage terminase small subunit P27 family -
  GWG10_RS17870 (GWG10_17885) - 3843585..3843965 (-) 381 WP_180911206.1 HNH endonuclease -
  GWG10_RS17875 (GWG10_17890) - 3844052..3844594 (-) 543 WP_180911207.1 DUF2514 domain-containing protein -
  GWG10_RS17880 (GWG10_17895) - 3844591..3845109 (-) 519 WP_180911208.1 lysozyme -
  GWG10_RS17885 (GWG10_17900) - 3845096..3845425 (-) 330 WP_180911209.1 phage holin, lambda family -
  GWG10_RS17890 (GWG10_17905) - 3845689..3846039 (-) 351 WP_180911210.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  GWG10_RS17895 (GWG10_17910) - 3846368..3847572 (+) 1205 WP_102948393.1 IS3 family transposase -
  GWG10_RS17900 (GWG10_17915) - 3848065..3849096 (-) 1032 WP_180911490.1 IS630 family transposase -
  GWG10_RS17905 (GWG10_17920) - 3849119..3850732 (-) 1614 WP_010674210.1 IS1634-like element ISAs25 family transposase -
  GWG10_RS17910 (GWG10_17925) - 3850925..3851977 (-) 1053 WP_180911211.1 hypothetical protein -
  GWG10_RS17915 (GWG10_17930) - 3851988..3852629 (-) 642 WP_180911212.1 type II secretion system protein J -
  GWG10_RS23280 (GWG10_17935) - 3852632..3853009 (-) 378 WP_413228158.1 GspH/FimT family protein -
  GWG10_RS17925 (GWG10_17940) - 3853053..3854267 (+) 1215 WP_025711969.1 IS256 family transposase -
  GWG10_RS23285 (GWG10_17945) comP 3854302..3854394 (-) 93 WP_180911214.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  GWG10_RS17935 (GWG10_17950) - 3854394..3854882 (-) 489 WP_180911215.1 type IV pilin protein -
  GWG10_RS17940 (GWG10_17955) - 3855061..3855723 (-) 663 WP_219635784.1 SOS response-associated peptidase -
  GWG10_RS17945 (GWG10_17960) umuD 3855851..3856267 (+) 417 WP_235687572.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
  GWG10_RS17950 (GWG10_17965) umuC 3856270..3857544 (+) 1275 WP_180911217.1 translesion error-prone DNA polymerase V subunit UmuC -
  GWG10_RS17955 (GWG10_17970) - 3857516..3857869 (-) 354 WP_180911218.1 hypothetical protein -
  GWG10_RS17960 (GWG10_17975) - 3858228..3859535 (+) 1308 WP_235687618.1 SIR2 family protein -
  GWG10_RS17965 (GWG10_17980) - 3859532..3861364 (+) 1833 WP_180911219.1 ATP-binding protein -
  GWG10_RS17970 (GWG10_17985) - 3861367..3861576 (+) 210 WP_180911220.1 KTSC domain-containing protein -
  GWG10_RS17975 (GWG10_17990) - 3861714..3862343 (-) 630 WP_180911221.1 antitermination protein -
  GWG10_RS17980 (GWG10_17995) - 3862343..3862696 (-) 354 WP_235687573.1 DUF1064 domain-containing protein -
  GWG10_RS17985 (GWG10_18000) - 3862693..3863682 (-) 990 WP_180911222.1 DUF968 domain-containing protein -
  GWG10_RS17990 (GWG10_18005) - 3863679..3863942 (-) 264 WP_180911223.1 hypothetical protein -
  GWG10_RS17995 (GWG10_18010) - 3863926..3864144 (-) 219 WP_180911224.1 DUF3283 family protein -
  GWG10_RS18000 (GWG10_18015) - 3864116..3864742 (-) 627 WP_180911225.1 3'-5' exonuclease -
  GWG10_RS18005 (GWG10_18020) - 3864773..3865582 (-) 810 WP_180911226.1 Bro-N domain-containing protein -
  GWG10_RS18010 (GWG10_18025) - 3865686..3866075 (-) 390 WP_113069713.1 DUF4406 domain-containing protein -
  GWG10_RS18015 (GWG10_18030) - 3866065..3866370 (-) 306 WP_180911227.1 hypothetical protein -
  GWG10_RS18020 (GWG10_18035) - 3866363..3866572 (-) 210 WP_042016738.1 hypothetical protein -
  GWG10_RS18025 (GWG10_18040) - 3866569..3866799 (-) 231 WP_234924017.1 hypothetical protein -
  GWG10_RS18030 (GWG10_18045) - 3866796..3867446 (-) 651 WP_219635786.1 hypothetical protein -
  GWG10_RS18035 (GWG10_18050) - 3867443..3867703 (-) 261 WP_180911228.1 hypothetical protein -
  GWG10_RS18040 (GWG10_18055) - 3867703..3868365 (-) 663 WP_180911229.1 replication protein P -
  GWG10_RS18045 (GWG10_18060) - 3868365..3869438 (-) 1074 WP_180911230.1 hypothetical protein -
  GWG10_RS18050 (GWG10_18065) - 3869778..3870224 (-) 447 WP_235687574.1 phage regulatory CII family protein -
  GWG10_RS18055 (GWG10_18070) - 3870250..3870516 (-) 267 WP_180911231.1 hypothetical protein -
  GWG10_RS18060 (GWG10_18075) - 3870621..3871304 (+) 684 WP_180911232.1 LexA family protein -
  GWG10_RS18065 (GWG10_18080) - 3872560..3872763 (+) 204 WP_180911233.1 hypothetical protein -
  GWG10_RS23015 - 3872798..3874546 (+) 1749 WP_235687575.1 phage N-6-adenine-methyltransferase -
  GWG10_RS18075 (GWG10_18090) - 3874543..3876354 (+) 1812 WP_180911234.1 DNA cytosine methyltransferase -
  GWG10_RS18080 (GWG10_18095) - 3876351..3876788 (+) 438 WP_113069703.1 hypothetical protein -
  GWG10_RS18085 (GWG10_18100) - 3876764..3876958 (+) 195 WP_180911235.1 hypothetical protein -
  GWG10_RS18090 (GWG10_18105) - 3877014..3877271 (+) 258 WP_180911236.1 hypothetical protein -
  GWG10_RS18095 (GWG10_18110) ssb 3877271..3877744 (+) 474 WP_180911237.1 single-stranded DNA-binding protein Machinery gene
  GWG10_RS18100 (GWG10_18115) xisR 3877811..3878020 (+) 210 WP_033130544.1 excisionase family protein -
  GWG10_RS18105 (GWG10_18120) - 3877996..3879303 (+) 1308 WP_180911238.1 site-specific integrase -

Sequence


Protein


Download         Length: 30 a.a.        Molecular weight: 3256.08 Da        Isoelectric Point: 5.8614

>NTDB_id=419019 GWG10_RS23285 WP_180911214.1 3854302..3854394(-) (comP) [Aeromonas caviae strain 1605-27183]
MSNRGFTLIELIVVILILVVLVTVGVPSFI

Nucleotide


Download         Length: 93 bp        

>NTDB_id=419019 GWG10_RS23285 WP_180911214.1 3854302..3854394(-) (comP) [Aeromonas caviae strain 1605-27183]
ATGAGTAATAGGGGATTTACTCTCATAGAGCTGATCGTAGTCATATTAATTCTAGTAGTTCTAGTTACTGTTGGTGTACC
CAGCTTTATTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria meningitidis 8013

62.963

90

0.567

  comP Neisseria gonorrhoeae MS11

62.963

90

0.567

  pilA/pilA3 Thermus thermophilus HB27

57.692

86.667

0.5

  pilY2 Acinetobacter baumannii D1279779

51.852

90

0.467

  pilA Haemophilus influenzae Rd KW20

53.846

86.667

0.467

  pilV Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

44.828

96.667

0.433

  pilA/pilA1 Synechocystis sp. PCC 6803

50

86.667

0.433

  pilE Neisseria gonorrhoeae strain FA1090

50

86.667

0.433

  fimT Acinetobacter baylyi ADP1

52

83.333

0.433

  pilE Neisseria gonorrhoeae MS11

50

86.667

0.433

  pilV Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

52

83.333

0.433

  pilW Acinetobacter baumannii D1279779

48.148

90

0.433

  comGC/cglC Streptococcus pneumoniae TIGR4

46.154

86.667

0.4

  pilA Vibrio parahaemolyticus RIMD 2210633

46.154

86.667

0.4

  comGC/cglC Streptococcus pneumoniae D39

46.154

86.667

0.4

  comGC/cglC Streptococcus pneumoniae R6

46.154

86.667

0.4

  comYC Streptococcus gordonii str. Challis substr. CH1

46.154

86.667

0.4

  comGC/cglC Streptococcus pneumoniae Rx1

46.154

86.667

0.4

  xcpW Acinetobacter baumannii D1279779

57.143

70

0.4

  comF Acinetobacter baylyi ADP1

48

83.333

0.4

  pilA/pilAII Pseudomonas stutzeri DSM 10701

42.857

93.333

0.4

  pilX Neisseria meningitidis 8013

41.379

96.667

0.4

  comYC Streptococcus suis isolate S10

41.379

96.667

0.4

  comGF Lactococcus lactis subsp. cremoris KW2

41.379

96.667

0.4

  pilL Neisseria gonorrhoeae MS11

41.379

96.667

0.4

  pilA Vibrio cholerae C6706

42.308

86.667

0.367

  pilA Vibrio cholerae strain A1552

42.308

86.667

0.367

  pilA Vibrio campbellii strain DS40M4

42.308

86.667

0.367

  pilA Vibrio cholerae O1 biovar El Tor strain E7946

42.308

86.667

0.367

  pilA Ralstonia pseudosolanacearum GMI1000

42.308

86.667

0.367

  pilA Acinetobacter baumannii strain A118

39.286

93.333

0.367

  comGD Latilactobacillus sakei subsp. sakei 23K

57.895

63.333

0.367

  comGF Latilactobacillus sakei subsp. sakei 23K

35.484

100

0.367

  fimT Legionella pneumophila strain Lp02

45.833

80

0.367

  ctsG Campylobacter jejuni subsp. jejuni 81-176

45.833

80

0.367


Multiple sequence alignment