Detailed information NTG0284570

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: C9I44_RS02725
• Genome accession: NZ_CP028386
• Coordinates: 518500..519990 (+)
• Length: 496 a.a.
• NCBI ID: WP_004259093.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain IBB3403
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 513500..524990

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9I44_RS02700 (C9I44_02670)	pfkB	513647..514573 (+)	927	WP_004259111.1	1-phosphofructokinase	-
C9I44_RS02705 (C9I44_02675)	-	514588..516492 (+)	1905	WP_004259108.1	fructose-specific PTS transporter subunit EIIC	-
C9I44_RS02710 (C9I44_02680)	-	516604..516846 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
C9I44_RS02715 (C9I44_02685)	-	517063..517614 (+)	552	WP_004259099.1	YceD family protein	-
C9I44_RS02720 (C9I44_02690)	covR	517716..518411 (+)	696	WP_004259096.1	response regulator transcription factor	Regulator
C9I44_RS02725 (C9I44_02695)	covS	518500..519990 (+)	1491	WP_004259093.1	HAMP domain-containing histidine kinase	Regulator
C9I44_RS02730 (C9I44_02700)	-	520387..521958 (+)	1572	WP_004259090.1	ABC transporter permease subunit	-
C9I44_RS02735 (C9I44_02705)	-	521959..522696 (+)	738	WP_004259087.1	amino acid ABC transporter ATP-binding protein	-
C9I44_RS02740 (C9I44_02710)	murD	522835..524196 (+)	1362	WP_004259085.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56726.70 Da
• Isoelectric Point: 5.1966

>NTDB_id=284570 C9I44_RS02725 WP_004259093.1 518500..519990(+) (covS) [Lactococcus garvieae strain IBB3403]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTSSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=284570 C9I44_RS02725 WP_004259093.1 518500..519990(+) (covS) [Lactococcus garvieae strain IBB3403]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAGTTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCAGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTAGAACGGTTGCACGATGCAATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTTAGTCATGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCTATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACGGGGCTTGGACTGTCTATTATTCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

• HAMP domain (HAMP) (214-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.734	100	0.558