Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00907  |
| T6SS type | Type iii |
| Strain | Bacteroides fragilis NCTC 9343 |
| Replicon (RefSeq) | chromosome (NC_003228) |
| Location | 2346972..2370693 |
| Function | anti-bacterial |
| Comment | Bacteroides fragilis targets B. thetaiotaomicron via T6SS; deletion of tssC in B. fragilis renders this species largely unable to reduce B. thetaiotaomicron growth. |
| References | [1] Russell AB et al (2014) A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism. Cell Host Microbe. 16(2):227-36. [PudMed:25070807] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssN | TssO | TssP |
| Number | 1 | 1 | 1 | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BF9343_RS09355 | 2344189..2344557 | - | 369 | 499302015 | hypothetical protein | ||
| BF9343_RS09360 | 2344598..2346970 | - | 2373 | 499302016 | type VI secretion system protein TssR | ||
| T6CP011043 | TssP | BF9343_RS09365 | 2346972..2347865 | - | 894 | 499302017 | PKD domain-containing protein |
| T6CP011327 | TssO | BF9343_RS09370 | 2347862..2348389 | - | 528 | 492268197 | type VI secretion system transmembrane protein TssO |
| T6CP011044 | TssO | BF9343_RS09375 | 2348402..2348905 | - | 504 | 492242849 | hypothetical protein |
| T6CP011045 | TssG | BF9343_RS09380 | 2348911..2349867 | - | 957 | 499302018 | type VI secretion system baseplate subunit TssG |
| T6CP011046 | TssK | BF9343_RS09385 | 2349869..2351011 | - | 1143 | 499302019 | hypothetical protein |
| T6CP011047 | TssN | BF9343_RS09390 | 2351039..2351887 | - | 849 | 499302020 | TssN family type VI secretion system protein |
| BF9343_RS09395 | 2352024..2352944 | - | 921 | 499302021 | hypothetical protein | ||
| BF9343_RS09400 | 2352949..2353995 | - | 1047 | 499302022 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01885 | BF9343_1937 (bte1) | Tse | IMU00365 | Bacteroides fragilis NCTC 9343 | chromosome (NC_003228) | 2364119..2364985 (-) | 60492942 |
| EFF01886 | BF9343_1928 (bte2) | Tse | IMU00366 ; IMU00367 | Bacteroides fragilis NCTC 9343 | chromosome (NC_003228) | 2353982..2356975 (-) | 60492933 |
Showing 1 to 2 of 2 rows
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00365 | BF9343_1936 (bti1) | EFF01885 | Bacteroides fragilis NCTC 9343 | chromosome (NC_003228) | 2363137..2364114 (-) | 60492941 |
| IMU00366 | BF9343_1926 (bti2b) | EFF01886 | Bacteroides fragilis NCTC 9343 | chromosome (NC_003228) | 2352024..2352944 (-) | 60492931 |
| IMU00367 | BF9343_1927 (bti2a) | EFF01886 | Bacteroides fragilis NCTC 9343 | chromosome (NC_003228) | 2352949..2353995 (-) | 60492932 |
Showing 1 to 3 of 3 rows
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||