Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00216  |
| T6SS type | Type i1 |
| Strain | Marinomonas sp. MWYL1 |
| Replicon (RefSeq) | chromosome (NC_009654) |
| Location | 1318734..1359652 |
| Function | - |
| Comment | - |
| References | [1] Bernard CS et al (2011) Regulation of type VI secretion gene clusters by sigma54 and cognate enhancer binding proteins. J Bacteriol. 193(9):2158-67. [PudMed:21378190] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM | VasH |
| Number | 1 | 2 | 1 | 1 | 3 | 1 | 1 | 1 | 1 | 4 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| MMWYL1_RS05985 | 1314962..1316563 | + | 1602 | WP_048814239.1 | isocitrate lyase | ||
| MMWYL1_RS05990 | 1316735..1318540 | + | 1806 | WP_012068896.1 | response regulator | ||
| T6CP008632 | TssD | MMWYL1_RS05995 | 1318734..1319252 | + | 519 | WP_012068897.1 | Hcp family type VI secretion system effector |
| T6CP002147 | TssI | MMWYL1_RS06000 (tssI) | 1319447..1321531 | + | 2085 | WP_012068898.1 | type VI secretion system tip protein VgrG |
| MMWYL1_RS06005 | 1321571..1322869 | + | 1299 | WP_012068899.1 | DUF4123 domain-containing protein | ||
| MMWYL1_RS06010 | 1322899..1324185 | + | 1287 | WP_012068900.1 | hypothetical protein | ||
| MMWYL1_RS06015 | 1324179..1324892 | + | 714 | WP_012068901.1 | hypothetical protein | ||
| MMWYL1_RS06020 | 1325046..1325558 | + | 513 | WP_012068902.1 | hypothetical protein | ||
| MMWYL1_RS06025 | 1325563..1326324 | + | 762 | WP_012068903.1 | hypothetical protein | ||
| MMWYL1_RS06030 | 1326604..1327065 | + | 462 | pseudogene | type VI secretion system tip protein VgrG | ||
| MMWYL1_RS06035 | 1327253..1327777 | + | 525 | WP_012068905.1 | DUF4123 domain-containing protein | ||
| MMWYL1_RS06040 | 1327774..1328811 | + | 1038 | WP_048813944.1 | LysM domain-containing protein | ||
| MMWYL1_RS06045 | 1328787..1331450 | + | 2664 | WP_012068907.1 | hypothetical protein | ||
| MMWYL1_RS06050 | 1331447..1332448 | + | 1002 | WP_048813946.1 | hypothetical protein | ||
| T6CP002149 | TssI | MMWYL1_RS06055 (tssI) | 1333278..1335245 | - | 1968 | WP_012068909.1 | type VI secretion system tip protein VgrG |
| T6CP009448 | TssD | MMWYL1_RS06060 | 1335440..1335958 | - | 519 | WP_012068910.1 | Hcp family type VI secretion system effector |
| T6CP002150 | TssB | MMWYL1_RS06065 (tssB) | 1336721..1337221 | + | 501 | WP_012068911.1 | type VI secretion system contractile sheath small subunit |
| T6CP002151 | TssC | MMWYL1_RS06070 (tssC) | 1337275..1338756 | + | 1482 | WP_012068912.1 | type VI secretion system contractile sheath large subunit |
| T6CP008633 | TssE | MMWYL1_RS06075 (tssE) | 1338761..1339198 | + | 438 | WP_012068913.1 | type VI secretion system baseplate subunit TssE |
| T6CP002152 | TssF | MMWYL1_RS06080 (tssF) | 1339201..1340967 | + | 1767 | WP_012068914.1 | type VI secretion system baseplate subunit TssF |
| T6CP002153 | TssG | MMWYL1_RS06085 (tssG) | 1340973..1341944 | + | 972 | WP_198135074.1 | type VI secretion system baseplate subunit TssG |
| T6CP011599 | FHA | MMWYL1_RS06090 (tagH) | 1341947..1343458 | + | 1512 | WP_012068916.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP002154 | TssJ | MMWYL1_RS06095 (tssJ) | 1343448..1343939 | + | 492 | WP_012068917.1 | type VI secretion system lipoprotein TssJ |
| T6CP002155 | TssK | MMWYL1_RS06100 (tssK) | 1343942..1345276 | + | 1335 | WP_012068918.1 | type VI secretion system baseplate subunit TssK |
| T6CP002156 | TssL | MMWYL1_RS06105 (icmH) | 1345279..1346055 | + | 777 | WP_012068919.1 | type IVB secretion system protein IcmH/DotU |
| T6CP002157 | TssH | MMWYL1_RS06110 (tssH) | 1346109..1348730 | + | 2622 | WP_012068920.1 | type VI secretion system ATPase TssH |
| T6CP012483 | VasH | MMWYL1_RS06115 | 1348733..1350283 | + | 1551 | WP_012068921.1 | sigma-54 dependent transcriptional regulator |
| MMWYL1_RS06120 (tagO) | 1350276..1350902 | + | 627 | WP_012068922.1 | type VI secretion system-associated protein TagO | ||
| T6CP008634 | TssA | MMWYL1_RS06125 (tssA) | 1350913..1352322 | + | 1410 | WP_012068923.1 | type VI secretion system protein TssA |
| T6CP002158 | TssM | MMWYL1_RS06130 (tssM) | 1352337..1355885 | + | 3549 | WP_012068924.1 | type VI secretion system membrane subunit TssM |
| T6CP008635 | TssA | MMWYL1_RS06135 | 1355932..1356609 | + | 678 | WP_012068925.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP008636 | TssD | MMWYL1_RS06140 | 1356826..1357344 | + | 519 | WP_012068897.1 | Hcp family type VI secretion system effector |
| T6CP002159 | TssI | MMWYL1_RS06145 (tssI) | 1357553..1359652 | + | 2100 | WP_012068926.1 | type VI secretion system tip protein VgrG |
| MMWYL1_RS06150 | 1359649..1360575 | + | 927 | WP_012068927.1 | DUF4123 domain-containing protein | ||
| MMWYL1_RS06155 | 1360572..1363964 | + | 3393 | WP_012068928.1 | LysM peptidoglycan-binding domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0183 |
Mmwyl1_1758 (bEBP/vasH) | protein | Global regulator | Marinomonas sp. MWYL1 | chromosome (NC_009654) | 1985170..1986666 (+) | 501016781 | T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓) |
| REG0184 |
Mmwyl1_2418 (RpoN) | protein | Global regulator | Marinomonas sp. MWYL1 | chromosome (NC_009654) | 2725212..2726687 (+) | 501017436 | T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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