Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   R5H38_RS03090 Genome accession   NZ_CP137602
Coordinates   594271..595620 (+) Length   449 a.a.
NCBI ID   WP_217469406.1    Uniprot ID   -
Organism   Streptococcus parasuis strain 221006     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 589271..600620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS03065 - 590315..590974 (-) 660 WP_217374818.1 amino acid ABC transporter permease -
  R5H38_RS03070 - 590989..591687 (-) 699 WP_217374819.1 amino acid ABC transporter permease -
  R5H38_RS03075 - 591701..592540 (-) 840 WP_318150841.1 transporter substrate-binding domain-containing protein -
  R5H38_RS03080 - 592550..593311 (-) 762 WP_130554350.1 amino acid ABC transporter ATP-binding protein -
  R5H38_RS03085 micA 593574..594278 (+) 705 WP_024391260.1 response regulator YycF Regulator
  R5H38_RS03090 micB 594271..595620 (+) 1350 WP_217469406.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R5H38_RS03095 vicX 595627..596430 (+) 804 WP_217374822.1 MBL fold metallo-hydrolase Regulator
  R5H38_RS03100 pbp2b 596749..598782 (+) 2034 WP_412080675.1 penicillin-binding protein PBP2B -
  R5H38_RS03105 recR 598791..599387 (+) 597 WP_172036408.1 recombination mediator RecR -
  R5H38_RS03110 - 599496..600542 (+) 1047 WP_318150842.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51032.42 Da        Isoelectric Point: 4.5615

>NTDB_id=899228 R5H38_RS03090 WP_217469406.1 594271..595620(+) (micB) [Streptococcus parasuis strain 221006]
MINQLRYLITTAEFWFVVILIGFLMALTVLLIENYRDNKQIQLLNKKVGALIDGNYSDVLDLRGSPEITEMANSLNDLSE
VIRLTHDNLEQEKIRLSSILSYMSDGVIATDRIGRIIMVNDMAQKQLGLKDHKQEQYFLLDVLELQDQYSLRELLSQTPE
IVLEKVNENQELLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGEMDVELINFTAFITFILNRFDQMKNSDVGKTYAIIRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGNITFSMKTTDSQLILSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWEEVAEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=899228 R5H38_RS03090 WP_217469406.1 594271..595620(+) (micB) [Streptococcus parasuis strain 221006]
ATGATTAATCAATTACGCTATCTAATTACAACAGCTGAATTTTGGTTTGTTGTTATTTTGATCGGATTTCTAATGGCGTT
GACAGTATTGTTGATAGAAAACTATCGTGACAATAAGCAGATTCAATTACTCAATAAAAAAGTTGGCGCCTTGATAGATG
GTAATTACTCTGATGTATTGGATTTACGAGGAAGTCCAGAGATTACCGAAATGGCAAATTCACTGAATGATTTGTCAGAA
GTAATCCGTTTAACGCACGATAACCTAGAACAAGAAAAAATCCGGCTCAGTTCCATTCTTTCCTACATGAGTGATGGAGT
CATTGCTACAGATCGTATTGGCCGAATTATCATGGTCAATGATATGGCGCAGAAACAACTGGGGTTAAAAGATCATAAAC
AGGAGCAGTATTTTTTACTTGATGTTCTAGAACTTCAAGACCAATATAGTCTGCGTGAGTTGTTATCTCAAACACCTGAA
ATCGTCTTAGAAAAAGTTAATGAGAATCAAGAATTACTGACCTTACGAGCTAATTTTGCAACGATTAGGAGTGAAAGTGG
GCTCATATCAGGGTTGGTTGTTGTCCTACATGATATGACGGAGCAGGCCAAGGAGGAACGTGAGCGCAGACTGTTTGTTT
CTAATGTCAGTCACGAATTGCGTACACCGTTGACCTCGGTTAAATCATATTTGGAAGCCTTGGATGAGGGAGCTCTGACC
GAATCGGTTGCCCCAAGTTTTGTCAAGGTATCCTTAGATGAAACCAACCGGATGATGCGGATGATTACAGATCTTTTAAG
TTTATCTCGCATTGATAATCAGGTTGGAGAGATGGATGTAGAGTTAATCAATTTTACAGCCTTTATCACTTTTATCTTGA
ATCGCTTTGATCAGATGAAGAATTCTGATGTTGGTAAGACCTACGCTATTATTCGTGATTACCAGATTAGTCCAATTTGG
GTTGAAATTGATACCGATAAGATGACGCAGGTACTGGATAATATTTTGAATAATGCTATCAAGTATTCTCCAGATGGAGG
AAATATTACCTTTAGTATGAAAACGACAGATAGTCAGCTTATTCTTTCTATTTCAGATGAAGGTTTGGGAATTCCTAAAG
CTGATTTACCTAAAATATTTGACCGTTTCTATCGAGTTGATAAAGCGCGTTCGAGAGCCCAAGGAGGCACAGGTTTAGGT
TTGGCGATTGCAAAAGAGATTGTAAAGCAACACAAAGGTTTCATTTGGGCTAAAAGTGAGTATGGACATGGTTCGACATT
TACAATTGTCTTACCATATAGTAAGGATATTGCACTGGATGAGTGGGAAGAGGTTGCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.266

97.105

0.673
  vicK Streptococcus mutans UA159

69.727

89.755

0.626