Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   R5H38_RS03085 Genome accession   NZ_CP137602
Coordinates   593574..594278 (+) Length   234 a.a.
NCBI ID   WP_024391260.1    Uniprot ID   A0A9X4MIJ1
Organism   Streptococcus parasuis strain 221006     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 588574..599278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS03065 - 590315..590974 (-) 660 WP_217374818.1 amino acid ABC transporter permease -
  R5H38_RS03070 - 590989..591687 (-) 699 WP_217374819.1 amino acid ABC transporter permease -
  R5H38_RS03075 - 591701..592540 (-) 840 WP_318150841.1 transporter substrate-binding domain-containing protein -
  R5H38_RS03080 - 592550..593311 (-) 762 WP_130554350.1 amino acid ABC transporter ATP-binding protein -
  R5H38_RS03085 micA 593574..594278 (+) 705 WP_024391260.1 response regulator YycF Regulator
  R5H38_RS03090 micB 594271..595620 (+) 1350 WP_217469406.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R5H38_RS03095 vicX 595627..596430 (+) 804 WP_217374822.1 MBL fold metallo-hydrolase Regulator
  R5H38_RS03100 pbp2b 596749..598782 (+) 2034 WP_412080675.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26727.72 Da        Isoelectric Point: 4.8061

>NTDB_id=899227 R5H38_RS03085 WP_024391260.1 593574..594278(+) (micA) [Streptococcus parasuis strain 221006]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALDIFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQGAVESSGTPELVIGDLVIVPDAFVAKKHGKELELT
HREFELLYHLAKHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYFIKAYD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=899227 R5H38_RS03085 WP_024391260.1 593574..594278(+) (micA) [Streptococcus parasuis strain 221006]
ATGAAGAAAATTTTAATTGTTGATGATGAGAAACCAATCTCGGATATTATTAAGTTCAATATGACACGTGAAGGATATGA
GGTAGTTACTGCGTTTGATGGACGTGAGGCGCTTGATATTTTTGAAGCAGAGTTTCCAGACATTGTTATTTTAGATTTAA
TGCTTCCAGAAATAGATGGATTAGAAGTAGCACGGACGATTCGAAAAACAAGTAATGTTCCTATTTTAATGTTGTCAGCT
AAAGATAGTGAGTTTGATAAAGTTATTGGGCTTGAAATTGGTGCGGATGACTATGTGACAAAGCCATTCTCAAACCGTGA
ATTACAGGCACGTGTAAAAGCTCTTCTTCGTCGAAGTGAATTGGCTGAGACGCAAGGAGCAGTTGAATCATCTGGTACTC
CAGAATTGGTAATCGGTGATTTGGTAATTGTTCCAGATGCTTTTGTAGCTAAGAAACATGGAAAAGAACTTGAACTAACA
CACCGTGAATTTGAATTATTGTATCACTTGGCCAAGCACATTGGGCAAGTCATGACGCGAGAGCATCTACTTGAGACTGT
TTGGGGATATGATTATTTTGGAGATGTACGTACTGTGGACGTGACAGTTCGACGCTTGCGTGAAAAAATTGAAGACACTC
CAAGTCGTCCGGAATACATCTTGACACGCAGGGGAGTAGGTTATTTTATAAAAGCTTATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.416

98.718

0.833
  vicR Streptococcus mutans UA159

80.851

100

0.812
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.043

98.291

0.423
  scnR Streptococcus mutans UA159

36.709

100

0.372