Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7616_RS04090 Genome accession   NZ_CP131717
Coordinates   788434..789654 (+) Length   406 a.a.
NCBI ID   WP_342120465.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2016N21-284     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 783434..794654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7616_RS04070 (Q7616_04075) corC 784396..785295 (-) 900 WP_005662987.1 CNNM family magnesium/cobalt transport protein CorC -
  Q7616_RS04075 (Q7616_04080) ampD 785928..786482 (-) 555 WP_050848915.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  Q7616_RS04080 (Q7616_04085) pilA 786597..787046 (+) 450 WP_342120462.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  Q7616_RS04085 (Q7616_04090) pilB 787043..788437 (+) 1395 WP_342120463.1 GspE/PulE family protein Machinery gene
  Q7616_RS04090 (Q7616_04095) pilC 788434..789654 (+) 1221 WP_342120465.1 type II secretion system F family protein Machinery gene
  Q7616_RS04095 (Q7616_04100) pilD 789651..790343 (+) 693 WP_105894637.1 A24 family peptidase Machinery gene
  Q7616_RS04100 (Q7616_04105) rho 790397..791659 (-) 1263 WP_112102455.1 transcription termination factor Rho -
  Q7616_RS04105 (Q7616_04110) metJ 791907..792224 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  Q7616_RS04110 (Q7616_04115) cueR 792238..792624 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  Q7616_RS04115 (Q7616_04120) - 792701..792907 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  Q7616_RS04120 (Q7616_04125) - 792981..793187 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  Q7616_RS04125 (Q7616_04130) - 793261..793467 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46338.60 Da        Isoelectric Point: 9.7793

>NTDB_id=864618 Q7616_RS04090 WP_342120465.1 788434..789654(+) (pilC) [Haemophilus influenzae strain 2016N21-284]
MTKKLFYYQGNNKLNQKQKGSIIADTKQQAHFQLINCGLTHIKLQQNWQFGTKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
YQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=864618 Q7616_RS04090 WP_342120465.1 788434..789654(+) (pilC) [Haemophilus influenzae strain 2016N21-284]
ATGACTAAAAAACTCTTTTATTATCAAGGCAACAACAAATTAAATCAAAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAACTGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGACAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAATCCGCAATTCCATTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTCCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
TATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

98.522

100

0.985
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.653

98.768

0.382