Detailed information NTG0819418

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO42_RS10655
• Genome accession: NZ_CP123139
• Coordinates: 2164572..2165459 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GE-MRSA22
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2159572..2170459

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO42_RS10625 (QAO42_10590)	-	2160303..2161064 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO42_RS10630 (QAO42_10595)	-	2161310..2161765 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO42_RS10635 (QAO42_10600)	-	2161887..2161988 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO42_RS10640 (QAO42_10605)	-	2162048..2163472 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO42_RS10645 (QAO42_10610)	-	2163670..2163870 (+)	201	WP_000604723.1	hypothetical protein	-
QAO42_RS10650 (QAO42_10615)	braR	2163896..2164561 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO42_RS10655 (QAO42_10620)	braS	2164572..2165459 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO42_RS10660 (QAO42_10625)	-	2165567..2166322 (+)	756	WP_000923771.1	ABC transporter ATP-binding protein	-
QAO42_RS10665 (QAO42_10630)	-	2166319..2168319 (+)	2001	WP_052995994.1	FtsX-like permease family protein	-
QAO42_RS10670 (QAO42_10635)	-	2168983..2169096 (+)	114	WP_072384844.1	hypothetical protein	-
QAO42_RS10675 (QAO42_10640)	-	2169478..2169738 (+)	261	WP_072434822.1	hypothetical protein	-
QAO42_RS10680 (QAO42_10645)	-	2169748..2170245 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO42_RS10685 (QAO42_10650)	-	2170353..2170441 (-)	89	Protein_2072	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=819418 QAO42_RS10655 WP_000143420.1 2164572..2165459(+) (braS) [Staphylococcus aureus strain GE-MRSA22]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819418 QAO42_RS10655 WP_000143420.1 2164572..2165459(+) (braS) [Staphylococcus aureus strain GE-MRSA22]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993