Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   QAO42_RS10650 Genome accession   NZ_CP123139
Coordinates   2163896..2164561 (+) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain GE-MRSA22     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2158896..2169561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO42_RS10625 (QAO42_10590) - 2160303..2161064 (+) 762 WP_000323451.1 alpha/beta hydrolase -
  QAO42_RS10630 (QAO42_10595) - 2161310..2161765 (+) 456 WP_000106184.1 MarR family winged helix-turn-helix transcriptional regulator -
  QAO42_RS10635 (QAO42_10600) - 2161887..2161988 (+) 102 WP_000731972.1 SE2200 family small protein -
  QAO42_RS10640 (QAO42_10605) - 2162048..2163472 (-) 1425 WP_000953731.1 alkaline phosphatase -
  QAO42_RS10645 (QAO42_10610) - 2163670..2163870 (+) 201 WP_000604723.1 hypothetical protein -
  QAO42_RS10650 (QAO42_10615) braR 2163896..2164561 (+) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  QAO42_RS10655 (QAO42_10620) braS 2164572..2165459 (+) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  QAO42_RS10660 (QAO42_10625) - 2165567..2166322 (+) 756 WP_000923771.1 ABC transporter ATP-binding protein -
  QAO42_RS10665 (QAO42_10630) - 2166319..2168319 (+) 2001 WP_052995994.1 FtsX-like permease family protein -
  QAO42_RS10670 (QAO42_10635) - 2168983..2169096 (+) 114 WP_072384844.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=819417 QAO42_RS10650 WP_000697883.1 2163896..2164561(+) (braR) [Staphylococcus aureus strain GE-MRSA22]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=819417 QAO42_RS10650 WP_000697883.1 2163896..2164561(+) (braR) [Staphylococcus aureus strain GE-MRSA22]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACGGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGACAATACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATTATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995