Detailed information NTG0537266

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: I6K87_RS06475
• Genome accession: NZ_CP069892
• Coordinates: 1321736..1322053 (-)
• Length: 105 a.a.
• NCBI ID: WP_003028473.1
• Uniprot ID: A0A0P0N5S2
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1316736..1327053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS06445 (I6K87_06445)	-	1318088..1319287 (-)	1200	WP_003028479.1	acetate kinase	-
I6K87_RS06450 (I6K87_06450)	comYH	1319334..1320287 (-)	954	WP_003039058.1	class I SAM-dependent methyltransferase	Machinery gene
I6K87_RS06455 (I6K87_06455)	comGG	1320355..1320681 (-)	327	WP_259334802.1	competence type IV pilus minor pilin ComGG	-
I6K87_RS06460 (I6K87_06460)	comGF/cglF	1320662..1321099 (-)	438	WP_204982485.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6K87_RS06465 (I6K87_06465)	comGE/cglE	1321083..1321376 (-)	294	WP_126406234.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6K87_RS06470 (I6K87_06470)	comYD	1321348..1321776 (-)	429	WP_037566697.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6K87_RS06475 (I6K87_06475)	comYC	1321736..1322053 (-)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
I6K87_RS06480 (I6K87_06480)	comYB	1322050..1323072 (-)	1023	WP_180363191.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6K87_RS06485 (I6K87_06485)	comYA	1323014..1323955 (-)	942	WP_003028470.1	competence type IV pilus ATPase ComGA	Machinery gene
I6K87_RS06490 (I6K87_06490)	-	1324025..1324390 (-)	366	WP_022525291.1	DUF1033 family protein	-
I6K87_RS06495 (I6K87_06495)	glnA	1324575..1325921 (-)	1347	WP_022525292.1	type I glutamate--ammonia ligase	-
I6K87_RS06500 (I6K87_06500)	-	1325960..1326319 (-)	360	WP_003028467.1	MerR family transcriptional regulator	-
I6K87_RS06505 (I6K87_06505)	-	1326396..1326926 (-)	531	WP_003028466.1	FUSC family protein	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11622.72 Da
• Isoelectric Point: 10.1006

>NTDB_id=537266 I6K87_RS06475 WP_003028473.1 1321736..1322053(-) (comYC) [Streptococcus anginosus strain FDAARGOS_1357]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=537266 I6K87_RS06475 WP_003028473.1 1321736..1322053(-) (comYC) [Streptococcus anginosus strain FDAARGOS_1357]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAGATGTTAGTCGTGCTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCGGTGACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAAGCGGAGCTGTTTGAGGTCAATCACACTAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGTACG
ATTACAGACAAGCAAGCGGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCCGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0P0N5S2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comYC	Streptococcus mutans UA159	66.667	100	0.667
comYC	Streptococcus mutans UA140	66.667	100	0.667
comGC/cglC	Streptococcus mitis NCTC 12261	68.627	97.143	0.667
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543