Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SMULJ23_RS08755 Genome accession   NC_017768
Coordinates   1811585..1812307 (-) Length   240 a.a.
NCBI ID   WP_002276223.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1806585..1817307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS08730 (SMULJ23_1718) sufU 1806620..1807054 (-) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -
  SMULJ23_RS08735 (SMULJ23_1719) - 1807041..1808270 (-) 1230 WP_014678250.1 cysteine desulfurase -
  SMULJ23_RS08740 (SMULJ23_1720) sufD 1808275..1809537 (-) 1263 WP_014678251.1 Fe-S cluster assembly protein SufD -
  SMULJ23_RS08745 (SMULJ23_1721) sufC 1809575..1810345 (-) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  SMULJ23_RS08750 (SMULJ23_1722) rgpG 1810419..1811579 (-) 1161 WP_002269696.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  SMULJ23_RS08755 (SMULJ23_1723) mecA 1811585..1812307 (-) 723 WP_002276223.1 adaptor protein MecA Regulator
  SMULJ23_RS08760 (SMULJ23_1724) - 1812397..1813242 (-) 846 WP_002270787.1 undecaprenyl-diphosphate phosphatase -
  SMULJ23_RS08765 (SMULJ23_1725) - 1813300..1815201 (-) 1902 WP_014678252.1 DUF2207 domain-containing protein -
  SMULJ23_RS08770 (SMULJ23_1726) - 1815353..1816906 (+) 1554 WP_002266996.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27997.61 Da        Isoelectric Point: 4.2574

>NTDB_id=50784 SMULJ23_RS08755 WP_002276223.1 1811585..1812307(-) (mecA) [Streptococcus mutans LJ23]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPENFKNSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=50784 SMULJ23_RS08755 WP_002276223.1 1811585..1812307(-) (mecA) [Streptococcus mutans LJ23]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATGCTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGAACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

98.75

100

0.988
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496

Multiple sequence alignment