Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SGGB_RS00630 Genome accession   NC_017576
Coordinates   99197..100138 (+) Length   313 a.a.
NCBI ID   WP_012961327.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 94197..105138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS00620 (SGGB_0085) rpoC 94949..98587 (+) 3639 WP_012961326.1 DNA-directed RNA polymerase subunit beta' -
  SGGB_RS00625 (SGGB_0086) - 98758..99126 (+) 369 WP_009853228.1 DUF1033 family protein -
  SGGB_RS00630 (SGGB_0087) comYA 99197..100138 (+) 942 WP_012961327.1 competence type IV pilus ATPase ComGA Machinery gene
  SGGB_RS00635 (SGGB_0088) comYB 100020..101105 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  SGGB_RS00640 (SGGB_0089) comYC 101105..101398 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  SGGB_RS00645 (SGGB_0090) comYD 101382..101813 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  SGGB_RS00650 (SGGB_0091) comGE 101767..102060 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  SGGB_RS00655 (SGGB_0092) comYF 102014..102481 (+) 468 WP_014619875.1 competence type IV pilus minor pilin ComGF Machinery gene
  SGGB_RS00660 (SGGB_0093) comYG 102453..102767 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  SGGB_RS00665 (SGGB_0094) comYH 102840..103796 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  SGGB_RS00670 (SGGB_0095) - 103849..105048 (+) 1200 WP_009853237.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35743.87 Da        Isoelectric Point: 5.3009

>NTDB_id=48886 SGGB_RS00630 WP_012961327.1 99197..100138(+) (comYA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MIQEKAKQLIKDAVEVNAQDIYILPREDCYEVYQRVGDQRQFVDYFELEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPNK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVIRASLTGAVVFSTIHAKSIPGV
YARLLELGVSQQELENSLRAIVYQRLIGGGGVIDFAKENFESHRPECWNTKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=48886 SGGB_RS00630 WP_012961327.1 99197..100138(+) (comYA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGATTCAGGAAAAAGCAAAGCAACTCATTAAGGATGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGACTGTTATGAAGTGTATCAACGCGTGGGAGACCAACGGCAATTTGTTGATTATTTTGAGCTAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCTGGTATGAATGTTGGGGAGAAACGTCGCAGCCAGCTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGTTTGTCGAGTGTTGGTGATTATCGTGGACGAGAAAGTTTAGTGATTCGCTT
GCTTTATTCTGGTCGTCATGATTTGCAATATTGGTTTGACGGGATGAAAAATATTTTAGAAGCCATTGATAGTAGGGGGC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTAATAAG
CAAGTTATTACAATTGAGGACCCTGTTGAAATCAAACAGGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGACGAGCTGATTAAATTATCGCTTCGCCATAGACCAGATATTCTGATTATCGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTCATTCGTGCGAGTTTGACGGGAGCTGTTGTATTTTCGACCATTCATGCGAAGAGCATCCCTGGCGTT
TATGCACGTCTTTTGGAATTAGGGGTTAGTCAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGCGGAGGAGGTGTGATTGATTTTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

69.132

99.361

0.687
  comYA Streptococcus mutans UA140

68.81

99.361

0.684
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.742

99.042

0.671
  comYA Streptococcus gordonii str. Challis substr. CH1

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.5

99.681

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

43.116

88.179

0.38

Multiple sequence alignment