Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SGGB_RS00635 Genome accession   NC_017576
Coordinates   100020..101105 (+) Length   361 a.a.
NCBI ID   WP_012961328.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 95020..106105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS00625 (SGGB_0086) - 98758..99126 (+) 369 WP_009853228.1 DUF1033 family protein -
  SGGB_RS00630 (SGGB_0087) comYA 99197..100138 (+) 942 WP_012961327.1 competence type IV pilus ATPase ComGA Machinery gene
  SGGB_RS00635 (SGGB_0088) comYB 100020..101105 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  SGGB_RS00640 (SGGB_0089) comYC 101105..101398 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  SGGB_RS00645 (SGGB_0090) comYD 101382..101813 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  SGGB_RS00650 (SGGB_0091) comGE 101767..102060 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  SGGB_RS00655 (SGGB_0092) comYF 102014..102481 (+) 468 WP_014619875.1 competence type IV pilus minor pilin ComGF Machinery gene
  SGGB_RS00660 (SGGB_0093) comYG 102453..102767 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  SGGB_RS00665 (SGGB_0094) comYH 102840..103796 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  SGGB_RS00670 (SGGB_0095) - 103849..105048 (+) 1200 WP_009853237.1 acetate kinase -
  SGGB_RS00675 (SGGB_0096) - 105279..105479 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  SGGB_RS00680 (SGGB_0097) - 105489..105698 (+) 210 WP_009853239.1 hypothetical protein -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 41149.94 Da        Isoelectric Point: 9.9289

>NTDB_id=48887 SGGB_RS00635 WP_012961328.1 100020..101105(+) (comYB) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MLKKTLKVTDQSAGIQKLKVLLKTDISQLNKQKSKKLPFKKQRKVIQLFNNLFESGFNLTEIVSFLRRSQLLLDIYVERM
QESLLNGASLATMMADLGFSDNIVTQIALADVHGNSQKSLLKIESYLSSMTVVRKKLIEVATYPLILLLFLILIMLGLKN
YLLPQLESQNVATQIITHFPTIFLLSIFSIGVLLVCATFYARRLSQIDLYSRISRIPLVGNYVRLYLTAYYAREWGNLIG
QGIELMAIVGIMQKQKSLLFQEIGKDMEEALLSGQAFHQKVLGYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQSFF
GKLTQATQLIQPLVFVFVALIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=48887 SGGB_RS00635 WP_012961328.1 100020..101105(+) (comYB) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
TTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAAGTCTTGTTAAAGACGGACATATC
ACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAAAAAACAGCGCAAGGTTATTCAACTCTTTAATAATCTTTTTG
AAAGTGGGTTTAATTTAACAGAAATCGTGTCTTTTCTCCGAAGAAGTCAATTGTTGTTAGACATTTATGTTGAGAGGATG
CAAGAAAGTTTGTTAAATGGTGCTAGCCTAGCAACAATGATGGCAGATTTAGGGTTTTCAGACAATATTGTCACACAAAT
TGCTTTGGCTGATGTTCATGGAAACAGTCAGAAAAGTCTGCTGAAGATTGAGTCTTACCTTTCTAGCATGACTGTCGTCA
GAAAAAAGTTAATTGAAGTTGCAACGTATCCATTGATTTTGTTGTTGTTTCTTATTTTGATTATGCTGGGGTTGAAGAAT
TATCTACTGCCACAGTTGGAAAGCCAAAATGTGGCAACGCAGATTATTACGCATTTTCCAACGATTTTTTTGCTAAGTAT
TTTCTCGATTGGAGTGTTGCTTGTTTGTGCGACATTTTATGCTAGGCGTTTATCGCAGATTGATTTATATAGTCGAATAA
GCCGGATTCCACTTGTGGGAAACTATGTTAGGTTATATTTGACAGCTTACTATGCGCGTGAATGGGGAAATTTGATTGGG
CAAGGTATTGAATTAATGGCAATCGTGGGAATCATGCAAAAGCAAAAGTCGCTCTTATTTCAAGAGATTGGAAAGGATAT
GGAAGAAGCGTTGCTTTCAGGGCAAGCTTTTCATCAAAAAGTTCTGGGCTATCCATTCTTTTTGCGAGAATTGAGCCTAA
TGATTGAATATGGTGAGGTCAAATCGAAGCTGGGACGTGAGTTAGACATTTATGCTGAGGAAACATGGCAGAGCTTTTTT
GGCAAATTGACTCAAGCAACACAGCTCATTCAACCACTTGTTTTTGTTTTTGTGGCTTTGATTATTGTGTTAATTTATGT
GGCAATGTTGTTGCCAATGTATCAAAATATGGGAGGAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(232-352)

Type II secretion system (T2SS), protein F (T2SSF)

(47-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

66.772

87.535

0.584
  comYB Streptococcus mutans UA159

66.456

87.535

0.582
  comGB/cglB Streptococcus mitis NCTC 12261

60.472

93.906

0.568
  comYB Streptococcus gordonii str. Challis substr. CH1

60.417

93.075

0.562
  comGB/cglB Streptococcus mitis SK321

57.864

93.352

0.54
  comGB/cglB Streptococcus pneumoniae Rx1

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae D39

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae R6

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae TIGR4

56.973

93.352

0.532
  comGB Lactococcus lactis subsp. cremoris KW2

50.292

94.737

0.476

Multiple sequence alignment