Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ACAM22_RS08855 Genome accession   NZ_AP028929
Coordinates   1908570..1908872 (-) Length   100 a.a.
NCBI ID   WP_369606700.1    Uniprot ID   A0AAT9G306
Organism   Streptococcus sp. SN-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1903570..1913872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS08825 (MASAN616_17060) rnpA 1904359..1904730 (-) 372 WP_369606696.1 ribonuclease P protein component -
  ACAM22_RS08830 (MASAN616_17070) - 1904880..1906070 (-) 1191 WP_369606697.1 acetate kinase -
  ACAM22_RS08835 (MASAN616_17080) comYH 1906121..1907074 (-) 954 WP_369606698.1 class I SAM-dependent methyltransferase Machinery gene
  ACAM22_RS08840 (MASAN616_17090) - 1907135..1907722 (-) 588 WP_261059675.1 class I SAM-dependent methyltransferase -
  ACAM22_RS08845 (MASAN616_17100) comGG/cglG 1907755..1908168 (-) 414 WP_173267826.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACAM22_RS08850 (MASAN616_17110) comGF/cglF 1908146..1908607 (-) 462 WP_369606699.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACAM22_RS08855 (MASAN616_17120) comGE/cglE 1908570..1908872 (-) 303 WP_369606700.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACAM22_RS08860 (MASAN616_17130) comGD/cglD 1908835..1909269 (-) 435 WP_369606701.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACAM22_RS08865 (MASAN616_17140) comGC/cglC 1909232..1909555 (-) 324 WP_000738640.1 comG operon protein ComGC Machinery gene
  ACAM22_RS08870 (MASAN616_17150) comGB/cglB 1909557..1910573 (-) 1017 WP_265529580.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACAM22_RS08875 (MASAN616_17160) comGA/cglA/cilD 1910521..1911462 (-) 942 WP_265529564.1 competence type IV pilus ATPase ComGA Machinery gene
  ACAM22_RS08880 (MASAN616_17170) - 1911541..1911906 (-) 366 WP_045606653.1 DUF1033 family protein -
  ACAM22_RS08885 (MASAN616_17180) - 1912058..1913116 (-) 1059 WP_369606702.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11264.27 Da        Isoelectric Point: 10.0959

>NTDB_id=107359 ACAM22_RS08855 WP_369606700.1 1908570..1908872(-) (comGE/cglE) [Streptococcus sp. SN-1]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLRQIQKNRQEEAKILQKEEVLRVAKMTLQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=107359 ACAM22_RS08855 WP_369606700.1 1908570..1908872(-) (comGE/cglE) [Streptococcus sp. SN-1]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTTGCTCTAGCTATCTT
TGCCAGCATTGCAACCCTCCTTTTGAGACAAATTCAGAAAAATAGGCAAGAAGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGACCTTGCAGACAGGTCAAAATCAGGTAAACATAAATGGAGTTGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

97

100

0.97
  comGE/cglE Streptococcus pneumoniae Rx1

97

100

0.97
  comGE/cglE Streptococcus pneumoniae D39

97

100

0.97
  comGE/cglE Streptococcus pneumoniae R6

97

100

0.97
  comGE/cglE Streptococcus pneumoniae TIGR4

97

100

0.97
  comGE/cglE Streptococcus mitis SK321

96

100

0.96
  comYE Streptococcus mutans UA140

42.222

90

0.38
  comYE Streptococcus mutans UA159

42.222

90

0.38

Multiple sequence alignment