Detailed information NTG0107358

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ACAM22_RS08850
• Genome accession: NZ_AP028929
• Coordinates: 1908146..1908607 (-)
• Length: 153 a.a.
• NCBI ID: WP_369606699.1
• Uniprot ID: A0AAT9G2X0
• Organism: Streptococcus sp. SN-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1903146..1913607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM22_RS08820 (MASAN616_17050)	-	1903560..1904384 (-)	825	WP_261059677.1	membrane protein insertase YidC	-
ACAM22_RS08825 (MASAN616_17060)	rnpA	1904359..1904730 (-)	372	WP_369606696.1	ribonuclease P protein component	-
ACAM22_RS08830 (MASAN616_17070)	-	1904880..1906070 (-)	1191	WP_369606697.1	acetate kinase	-
ACAM22_RS08835 (MASAN616_17080)	comYH	1906121..1907074 (-)	954	WP_369606698.1	class I SAM-dependent methyltransferase	Machinery gene
ACAM22_RS08840 (MASAN616_17090)	-	1907135..1907722 (-)	588	WP_261059675.1	class I SAM-dependent methyltransferase	-
ACAM22_RS08845 (MASAN616_17100)	comGG/cglG	1907755..1908168 (-)	414	WP_173267826.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACAM22_RS08850 (MASAN616_17110)	comGF/cglF	1908146..1908607 (-)	462	WP_369606699.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACAM22_RS08855 (MASAN616_17120)	comGE/cglE	1908570..1908872 (-)	303	WP_369606700.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACAM22_RS08860 (MASAN616_17130)	comGD/cglD	1908835..1909269 (-)	435	WP_369606701.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACAM22_RS08865 (MASAN616_17140)	comGC/cglC	1909232..1909555 (-)	324	WP_000738640.1	comG operon protein ComGC	Machinery gene
ACAM22_RS08870 (MASAN616_17150)	comGB/cglB	1909557..1910573 (-)	1017	WP_265529580.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACAM22_RS08875 (MASAN616_17160)	comGA/cglA/cilD	1910521..1911462 (-)	942	WP_265529564.1	competence type IV pilus ATPase ComGA	Machinery gene
ACAM22_RS08880 (MASAN616_17170)	-	1911541..1911906 (-)	366	WP_045606653.1	DUF1033 family protein	-
ACAM22_RS08885 (MASAN616_17180)	-	1912058..1913116 (-)	1059	WP_369606702.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17934.57 Da
• Isoelectric Point: 8.8086

>NTDB_id=107358 ACAM22_RS08850 WP_369606699.1 1908146..1908607(-) (comGF/cglF) [Streptococcus sp. SN-1]
MVQNSCWLSKSHKVKAFTLLESLIALIVISGSLLLFQDMSQLLISEVRYQQQSEQKEWLLFVHQLEAELDRSQFEKVEGN
RLYMKQDGKEIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=107358 ACAM22_RS08850 WP_369606699.1 1908146..1908607(-) (comGF/cglF) [Streptococcus sp. SN-1]
ATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTGGAATCCTTGATTGCCCTTAT
TGTCATCAGTGGGAGCCTACTCCTCTTTCAAGACATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAACAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGCACCAGCTGGAGGCAGAATTAGACCGTTCGCAATTCGAAAAAGTGGAGGGCAAT
CGCCTCTATATGAAGCAGGATGGCAAGGAAATTGCGATAGGTAAGTCAAAATCGGATGATTTTCGTAAAACCGATGCTAG
TGGACGGGGTTATCAGCCTATGGTTTATGGCCTCAAATCCGCTCAGATTACAGAGGACAATCAGTTGGTGCGTTTTCGTT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae Rx1	92.157	100	0.922
comGF/cglF	Streptococcus pneumoniae D39	92.157	100	0.922
comGF/cglF	Streptococcus pneumoniae R6	92.157	100	0.922
comGF/cglF	Streptococcus pneumoniae TIGR4	92.157	100	0.922
comGF	Lactococcus lactis subsp. cremoris KW2	40	91.503	0.366