Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   ACAM22_RS08865 Genome accession   NZ_AP028929
Coordinates   1909232..1909555 (-) Length   107 a.a.
NCBI ID   WP_000738640.1    Uniprot ID   A0AAT9G2Z7
Organism   Streptococcus sp. SN-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1904232..1914555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS08825 (MASAN616_17060) rnpA 1904359..1904730 (-) 372 WP_369606696.1 ribonuclease P protein component -
  ACAM22_RS08830 (MASAN616_17070) - 1904880..1906070 (-) 1191 WP_369606697.1 acetate kinase -
  ACAM22_RS08835 (MASAN616_17080) comYH 1906121..1907074 (-) 954 WP_369606698.1 class I SAM-dependent methyltransferase Machinery gene
  ACAM22_RS08840 (MASAN616_17090) - 1907135..1907722 (-) 588 WP_261059675.1 class I SAM-dependent methyltransferase -
  ACAM22_RS08845 (MASAN616_17100) comGG/cglG 1907755..1908168 (-) 414 WP_173267826.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACAM22_RS08850 (MASAN616_17110) comGF/cglF 1908146..1908607 (-) 462 WP_369606699.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACAM22_RS08855 (MASAN616_17120) comGE/cglE 1908570..1908872 (-) 303 WP_369606700.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACAM22_RS08860 (MASAN616_17130) comGD/cglD 1908835..1909269 (-) 435 WP_369606701.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACAM22_RS08865 (MASAN616_17140) comGC/cglC 1909232..1909555 (-) 324 WP_000738640.1 comG operon protein ComGC Machinery gene
  ACAM22_RS08870 (MASAN616_17150) comGB/cglB 1909557..1910573 (-) 1017 WP_265529580.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACAM22_RS08875 (MASAN616_17160) comGA/cglA/cilD 1910521..1911462 (-) 942 WP_265529564.1 competence type IV pilus ATPase ComGA Machinery gene
  ACAM22_RS08880 (MASAN616_17170) - 1911541..1911906 (-) 366 WP_045606653.1 DUF1033 family protein -
  ACAM22_RS08885 (MASAN616_17180) - 1912058..1913116 (-) 1059 WP_369606702.1 zinc-dependent alcohol dehydrogenase family protein -
  ACAM22_RS08890 (MASAN616_17190) nagA 1913277..1914428 (-) 1152 WP_101786331.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 11999.19 Da        Isoelectric Point: 10.0527

>NTDB_id=107361 ACAM22_RS08865 WP_000738640.1 1909232..1909555(-) (comGC/cglC) [Streptococcus sp. SN-1]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITEEQAKAYKEYHAKQNKTQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=107361 ACAM22_RS08865 WP_000738640.1 1909232..1909555(-) (comGC/cglC) [Streptococcus sp. SN-1]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACACTTGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTCTATTACTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAGCTTTATAGCTTGGATAAAAATGAAGATGCTAGCTTAAGTAAGTTACAAGCA
GATGGGCGAATCACAGAAGAGCAAGCTAAAGCTTATAAAGAATATCATGCAAAACAAAATAAGACTCAAACGGTCGCGGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

98.131

100

0.981
  comGC/cglC Streptococcus mitis SK321

96

93.458

0.897
  comGC/cglC Streptococcus pneumoniae Rx1

94

93.458

0.879
  comGC/cglC Streptococcus pneumoniae D39

94

93.458

0.879
  comGC/cglC Streptococcus pneumoniae R6

94

93.458

0.879
  comGC/cglC Streptococcus pneumoniae TIGR4

93

93.458

0.869
  comYC Streptococcus gordonii str. Challis substr. CH1

70.476

98.131

0.692
  comYC Streptococcus mutans UA140

66.346

97.196

0.645
  comYC Streptococcus mutans UA159

66.346

97.196

0.645
  comYC Streptococcus suis isolate S10

70.37

75.701

0.533
  comGC Lactococcus lactis subsp. cremoris KW2

57.732

90.654

0.523
  comGC Staphylococcus aureus MW2

51.163

80.374

0.411
  comGC Staphylococcus aureus N315

51.163

80.374

0.411

Multiple sequence alignment