Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   ACAM22_RS08875 Genome accession   NZ_AP028929
Coordinates   1910521..1911462 (-) Length   313 a.a.
NCBI ID   WP_265529564.1    Uniprot ID   A0AAT9G347
Organism   Streptococcus sp. SN-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1905521..1916462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS08835 (MASAN616_17080) comYH 1906121..1907074 (-) 954 WP_369606698.1 class I SAM-dependent methyltransferase Machinery gene
  ACAM22_RS08840 (MASAN616_17090) - 1907135..1907722 (-) 588 WP_261059675.1 class I SAM-dependent methyltransferase -
  ACAM22_RS08845 (MASAN616_17100) comGG/cglG 1907755..1908168 (-) 414 WP_173267826.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACAM22_RS08850 (MASAN616_17110) comGF/cglF 1908146..1908607 (-) 462 WP_369606699.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACAM22_RS08855 (MASAN616_17120) comGE/cglE 1908570..1908872 (-) 303 WP_369606700.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACAM22_RS08860 (MASAN616_17130) comGD/cglD 1908835..1909269 (-) 435 WP_369606701.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACAM22_RS08865 (MASAN616_17140) comGC/cglC 1909232..1909555 (-) 324 WP_000738640.1 comG operon protein ComGC Machinery gene
  ACAM22_RS08870 (MASAN616_17150) comGB/cglB 1909557..1910573 (-) 1017 WP_265529580.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACAM22_RS08875 (MASAN616_17160) comGA/cglA/cilD 1910521..1911462 (-) 942 WP_265529564.1 competence type IV pilus ATPase ComGA Machinery gene
  ACAM22_RS08880 (MASAN616_17170) - 1911541..1911906 (-) 366 WP_045606653.1 DUF1033 family protein -
  ACAM22_RS08885 (MASAN616_17180) - 1912058..1913116 (-) 1059 WP_369606702.1 zinc-dependent alcohol dehydrogenase family protein -
  ACAM22_RS08890 (MASAN616_17190) nagA 1913277..1914428 (-) 1152 WP_101786331.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACAM22_RS08895 (MASAN616_17200) - 1914580..1916397 (-) 1818 WP_369606703.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35562.53 Da        Isoelectric Point: 5.8157

>NTDB_id=107363 ACAM22_RS08875 WP_265529564.1 1910521..1911462(-) (comGA/cglA/cilD) [Streptococcus sp. SN-1]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGCYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDDKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQDNMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGVTVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANKDYQEHQPTSWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=107363 ACAM22_RS08875 WP_265529564.1 1910521..1911462(-) (comGA/cglA/cilD) [Streptococcus sp. SN-1]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCCCGGAAAAAAGGGGCGCAGGATATTTATTTTGTCCCTAAGCT
CGACGCTTATGAGCTTCATATGAGGGTAGGAGATGAGCGTTGTAAAATTGGTTGTTATGATTTTGAAAAGTTTGCTGCCG
TTATCAGCCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAGCGACGTAGTCAGCTTGGTTCCTGCGATTATGCT
TATGACGATAAGATGGCGTCCTTACGTTTATCTACCGTAGGCGATTATCGAGGGCATGAGAGTTTAGTTATTCGCTTGTT
GCATGATGAGGAGCAGGATTTGCATTTTTGGTTTCAGGATATCGAAGAACTGGGCAAGCAGTATAGGCAACGTGGTCTCT
ATCTTTTTGCTGGTCCGGTCGGCAGTGGCAAGACGACCTTGATGCATGAATTGGCTAAATCTCTCTTTAAAGGACAGCAA
GTTATGTCCATTGAAGATCCTGTCGAAATCAAGCAGGACAACATGCTCCAGTTGCAGTTGAATGAGGCGATTGGGCTTAC
CTATGAAAATCTAATCAAACTTTCCTTGCGCCATCGACCAGATCTCTTGATTATCGGAGAAATTCGGGACAGCGAGACGG
CGCGTGCAGTAGTTAGAGCTAGTTTGACAGGGGTAACAGTCTTTTCAACCATTCATGCCAAGAGTATTCGAGGTGTTTAT
GAGCGCCTGCTGGAGTTGGGTGTGAGTGAGGAGGAATTAGCAGTCGTTCTTCAAGGAGTCTGCTACCAGAGATTAATTGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTATCAAGAACACCAGCCAACTAGCTGGAATGAGCAGATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

96.166

100

0.962
  comGA/cglA/cilD Streptococcus pneumoniae D39

96.166

100

0.962
  comGA/cglA/cilD Streptococcus pneumoniae R6

96.166

100

0.962
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

96.166

100

0.962
  comYA Streptococcus gordonii str. Challis substr. CH1

78.71

99.042

0.78
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

42.647

86.901

0.371

Multiple sequence alignment