Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   ACAM22_RS08870 Genome accession   NZ_AP028929
Coordinates   1909557..1910573 (-) Length   338 a.a.
NCBI ID   WP_265529580.1    Uniprot ID   -
Organism   Streptococcus sp. SN-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1904557..1915573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS08830 (MASAN616_17070) - 1904880..1906070 (-) 1191 WP_369606697.1 acetate kinase -
  ACAM22_RS08835 (MASAN616_17080) comYH 1906121..1907074 (-) 954 WP_369606698.1 class I SAM-dependent methyltransferase Machinery gene
  ACAM22_RS08840 (MASAN616_17090) - 1907135..1907722 (-) 588 WP_261059675.1 class I SAM-dependent methyltransferase -
  ACAM22_RS08845 (MASAN616_17100) comGG/cglG 1907755..1908168 (-) 414 WP_173267826.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACAM22_RS08850 (MASAN616_17110) comGF/cglF 1908146..1908607 (-) 462 WP_369606699.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACAM22_RS08855 (MASAN616_17120) comGE/cglE 1908570..1908872 (-) 303 WP_369606700.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACAM22_RS08860 (MASAN616_17130) comGD/cglD 1908835..1909269 (-) 435 WP_369606701.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACAM22_RS08865 (MASAN616_17140) comGC/cglC 1909232..1909555 (-) 324 WP_000738640.1 comG operon protein ComGC Machinery gene
  ACAM22_RS08870 (MASAN616_17150) comGB/cglB 1909557..1910573 (-) 1017 WP_265529580.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACAM22_RS08875 (MASAN616_17160) comGA/cglA/cilD 1910521..1911462 (-) 942 WP_265529564.1 competence type IV pilus ATPase ComGA Machinery gene
  ACAM22_RS08880 (MASAN616_17170) - 1911541..1911906 (-) 366 WP_045606653.1 DUF1033 family protein -
  ACAM22_RS08885 (MASAN616_17180) - 1912058..1913116 (-) 1059 WP_369606702.1 zinc-dependent alcohol dehydrogenase family protein -
  ACAM22_RS08890 (MASAN616_17190) nagA 1913277..1914428 (-) 1152 WP_101786331.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38496.51 Da        Isoelectric Point: 9.5998

>NTDB_id=107362 ACAM22_RS08870 WP_265529580.1 1909557..1910573(-) (comGB/cglB) [Streptococcus sp. SN-1]
MDISQVFRLKRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRTGLSQGKSFSEMMESLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRSYLLPQLDSSNIATQIIGNLPQIF
LGMVGFVSILVLLALTFYKRSSKMRVFSILARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQSLQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=107362 ACAM22_RS08870 WP_265529580.1 1909557..1910573(-) (comGB/cglB) [Streptococcus sp. SN-1]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCTTGTTTAA
CAATCTCTTTTCCAGCGGTTTTCATCTGGTAGAGACTATCTCCTTTTTAGATAGGAGTGCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGCACGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGCTTTTCAAGTGCCATT
GTCACTCAGTTATCCCTAGCGGAAGTCCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
AGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCCTTGATTTTACTGGGATTTCTTCTCTTAATTATGCTGG
GGCTACGTAGCTACCTACTACCACAACTGGATAGTAGTAATATTGCCACCCAAATTATCGGAAATCTGCCACAAATCTTT
CTAGGAATGGTAGGATTTGTTTCCATACTTGTCCTTTTAGCACTCACTTTTTATAAAAGAAGTTCTAAGATGCGCGTCTT
TTCTATCTTAGCACGCATTCCTTTTCTTGGAATCTTTGTGCAGACTTATCTGACAGCTTATTATGCGCGTGAATGGGGTA
ATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAAATCATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATTTAGCTCAATCCCTACAAAATGGCCGCGAATTTTCTCAAACCATAGCAACCTATCCTTTCTTTAAAAAAGA
GTTGAGTCTCATCATCGAGTATGGTGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTTAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

98.225

100

0.982
  comGB/cglB Streptococcus mitis NCTC 12261

97.041

100

0.97
  comGB/cglB Streptococcus pneumoniae Rx1

95.266

100

0.953
  comGB/cglB Streptococcus pneumoniae D39

95.266

100

0.953
  comGB/cglB Streptococcus pneumoniae R6

95.266

100

0.953
  comGB/cglB Streptococcus pneumoniae TIGR4

95.266

100

0.953
  comYB Streptococcus gordonii str. Challis substr. CH1

72.619

99.408

0.722
  comYB Streptococcus mutans UA140

57.595

93.491

0.538
  comYB Streptococcus mutans UA159

57.595

93.491

0.538
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5

Multiple sequence alignment