Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00910  |
| T6SS type | Type iii |
| Strain | Flavobacterium johnsoniae UW101 |
| Replicon (RefSeq) | chromosome (NC_009441) |
| Location | 3892562..3923100 |
| Function | anti-bacterial; effector translocation |
| Comment | A T6SS pathway exports antibacterial effectors; T6SS mediates interspecies bacterial antagonism. |
| References | [1] Russell AB et al (2014) A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism. Cell Host Microbe. 16(2):227-36. [PudMed:25070807] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssN | TssO | TssP |
| Number | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| FJOH_RS16860 | 3890555..3891481 | - | 927 | WP_012025237.1 | FecR domain-containing protein | ||
| FJOH_RS16865 | 3891596..3892153 | - | 558 | WP_012025238.1 | RNA polymerase sigma-70 factor | ||
| T6CP011089 | TssF | FJOH_RS16870 | 3892562..3894397 | - | 1836 | WP_012025239.1 | type VI secretion system baseplate subunit TssF |
| FJOH_RS16875 | 3894394..3894747 | - | 354 | WP_123875728.1 | carboxypeptidase-like regulatory domain-containing protein | ||
| FJOH_RS16880 | 3894891..3895379 | - | 489 | WP_012025240.1 | hypothetical protein | ||
| FJOH_RS16885 | 3895387..3895947 | - | 561 | WP_012025241.1 | hypothetical protein | ||
| FJOH_RS16890 | 3895944..3897596 | - | 1653 | WP_012025242.1 | hypothetical protein | ||
| FJOH_RS16895 | 3897690..3898187 | - | 498 | WP_012025243.1 | hypothetical protein | ||
| FJOH_RS16900 | 3898194..3899840 | - | 1647 | WP_012025244.1 | DUF3289 family protein | ||
| T6CP011090 | TssI | FJOH_RS16905 | 3899844..3901652 | - | 1809 | WP_012025245.1 | type IV secretion protein Rhs |
| T6CP011091 | TssD | FJOH_RS16910 | 3901691..3902086 | - | 396 | WP_012025246.1 | hypothetical protein |
| T6CP011092 | TssD | FJOH_RS16915 | 3902237..3902623 | - | 387 | WP_012025247.1 | hypothetical protein |
| T6CP011093 | TssE | FJOH_RS16920 | 3902805..3903236 | - | 432 | WP_012025248.1 | GPW/gp25 family protein |
| FJOH_RS16925 | 3903250..3903963 | - | 714 | WP_012025249.1 | hypothetical protein | ||
| FJOH_RS16930 | 3904022..3904549 | - | 528 | WP_012025250.1 | hypothetical protein | ||
| T6CP011094 | TssC | FJOH_RS16935 | 3904650..3906020 | - | 1371 | WP_012025251.1 | DUF5458 family protein |
| T6CP011095 | TssB | FJOH_RS16940 | 3906041..3906490 | - | 450 | WP_012025252.1 | hypothetical protein |
| T6CP011096 | TssO | FJOH_RS16945 | 3906545..3907057 | - | 513 | WP_012025253.1 | hypothetical protein |
| T6CP011097 | TssK | FJOH_RS16950 | 3907083..3908252 | - | 1170 | WP_012025254.1 | hypothetical protein |
| FJOH_RS16955 | 3908526..3909506 | - | 981 | WP_012025255.1 | hypothetical protein | ||
| FJOH_RS16960 | 3909608..3910762 | - | 1155 | WP_012025256.1 | SH3 domain-containing protein | ||
| FJOH_RS16965 | 3910884..3911552 | - | 669 | WP_012025257.1 | hypothetical protein | ||
| FJOH_RS16970 | 3911564..3912304 | - | 741 | WP_012025258.1 | hypothetical protein | ||
| FJOH_RS16975 | 3912310..3915042 | - | 2733 | WP_012025259.1 | hypothetical protein | ||
| FJOH_RS16980 | 3915054..3915548 | - | 495 | WP_012025260.1 | DUF4280 domain-containing protein | ||
| FJOH_RS16985 | 3915601..3916674 | - | 1074 | WP_012025261.1 | LysM peptidoglycan-binding domain-containing protein | ||
| T6CP011098 | TssN | FJOH_RS16990 | 3916691..3917662 | - | 972 | WP_012025262.1 | TssN family type VI secretion system protein |
| T6CP011099 | TssG | FJOH_RS16995 | 3917665..3918609 | - | 945 | WP_012025263.1 | type VI secretion system baseplate subunit TssG |
| FJOH_RS17000 | 3918593..3919234 | - | 642 | WP_044047808.1 | C40 family peptidase | ||
| T6CP011100 | TssP | FJOH_RS17005 | 3919581..3920633 | + | 1053 | WP_012025265.1 | PKD domain-containing protein |
| T6CP011101 | TssH | FJOH_RS17010 | 3920641..3923100 | + | 2460 | WP_012025266.1 | ATP-dependent Clp protease ATP-binding subunit |
| FJOH_RS17015 | 3923199..3923441 | - | 243 | WP_052295196.1 | hypothetical protein | ||
| FJOH_RS17020 | 3923481..3925880 | - | 2400 | WP_012025268.1 | arylsulfatase | ||
| FJOH_RS17025 | 3925903..3927384 | - | 1482 | WP_012025269.1 | DUF1254 domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01311 |
Fjoh_3257 (Fte1) | Tse | IMU00057 |
Flavobacterium johnsoniae UW101 | chromosome (NC_009441) | 3895944..3897596 (-) | 146301001 |
| EFF01312 |
FJOH_RS16975 | - | - | Flavobacterium johnsoniae UW101 | chromosome (NC_009441) | 3912310..3915042 (-) | 146301018 |
| EFF01316 |
FJOH_RS16905 | - | - | Flavobacterium johnsoniae UW101 | chromosome (NC_009441) | 3899844..3901652 (-) | 146301004 |
| EFF01317 |
FJOH_RS16915 | - | - | Flavobacterium johnsoniae UW101 | chromosome (NC_009441) | 3902237..3902623 (-) | 146301006 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00057 |
Fjoh_3256 (Fti1) | EFF01311 |
Flavobacterium johnsoniae UW101 | chromosome (NC_009441) | 3895387..3895947 (-) | 146301000 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|