Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00764  |
| T6SS type | Type i3 |
| Strain | Pseudomonas protegens CHA0 |
| Replicon (RefSeq) | chromosome (NC_021237) |
| Location | 6697981..6718631 |
| Function | anti-bacterial; anti-eukaryotic |
| Comment | The T6SS contributes to insect pathogenicity of P. protegens following oral infection and modules of Pseudomonas protegens CHA0 to the colonization of the gut |
| References | [1] Vacheron J, P��chy-Tarr M, Brochet S, Heiman CM, Stojiljkovic M, Maurhofer M, Keel C. et al (2019) T6SS contributes to gut microbiome invasion and killing of an herbivorous pest insect by plant-beneficial Pseudomonas protegens.. ISME J. 13(5):1318-1329. [PudMed:30683920] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | PpkA | PppA | TagF | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| T6CP012592 | PpkA | PFLCHA0_RS30105 | 6693510..6696593 | - | 3084 | WP_015637479.1 | serine/threonine-protein kinase |
| T6CP012593 | PppA | PFLCHA0_RS30110 | 6696596..6697330 | - | 735 | WP_011064247.1 | protein phosphatase 2C domain-containing protein |
| T6CP012594 | TagF | PFLCHA0_RS30115 (tagF) | 6697331..6697984 | - | 654 | WP_011064248.1 | type VI secretion system-associated protein TagF |
| T6CP008065 | TssM | PFLCHA0_RS30120 (tssM) | 6697981..6701487 | - | 3507 | WP_015637480.1 | type VI secretion system membrane subunit TssM |
| T6CP008066 | TssL | PFLCHA0_RS30125 | 6701484..6702809 | - | 1326 | WP_015637481.1 | DotU family type VI secretion system protein |
| T6CP008067 | TssK | PFLCHA0_RS30130 (tssK) | 6702816..6704150 | - | 1335 | WP_011064251.1 | type VI secretion system baseplate subunit TssK |
| T6CP008068 | TssJ | PFLCHA0_RS30135 (tssJ) | 6704166..6704672 | - | 507 | WP_011064252.1 | type VI secretion system lipoprotein TssJ |
| T6CP012265 | FHA | PFLCHA0_RS30140 (tagH) | 6704737..6706221 | - | 1485 | WP_011064253.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP008069 | TssA | PFLCHA0_RS30145 (tssA) | 6706614..6707633 | + | 1020 | WP_041752688.1 | type VI secretion system protein TssA |
| T6CP008070 | TssB | PFLCHA0_RS30150 (tssB) | 6707715..6708230 | + | 516 | WP_011064255.1 | type VI secretion system contractile sheath small subunit |
| T6CP008071 | TssC | PFLCHA0_RS30155 (tssC) | 6708247..6709740 | + | 1494 | WP_011064256.1 | type VI secretion system contractile sheath large subunit |
| T6CP008072 | TssD | PFLCHA0_RS30160 | 6709859..6710347 | + | 489 | WP_011064257.1 | type VI secretion system tube protein Hcp |
| T6CP008073 | TssE | PFLCHA0_RS30165 (tssE) | 6710508..6711023 | + | 516 | WP_011064258.1 | type VI secretion system baseplate subunit TssE |
| T6CP008074 | TssF | PFLCHA0_RS30170 (tssF) | 6711020..6712879 | + | 1860 | WP_011064259.1 | type VI secretion system baseplate subunit TssF |
| T6CP008075 | TssG | PFLCHA0_RS30175 (tssG) | 6712843..6713895 | + | 1053 | WP_011064260.1 | type VI secretion system baseplate subunit TssG |
| T6CP008076 | TssH | PFLCHA0_RS30180 (tssH) | 6713888..6716563 | + | 2676 | WP_015637485.1 | type VI secretion system ATPase TssH |
| T6CP008077 | TssI | PFLCHA0_RS30185 | 6716694..6718631 | + | 1938 | WP_011064262.1 | type VI secretion system tip protein VgrG |
| PFLCHA0_RS30190 | 6718650..6719075 | + | 426 | WP_011064263.1 | DUF1795 domain-containing protein | ||
| T6CP012266 | PAAR | PFLCHA0_RS30195 | 6719085..6723545 | + | 4461 | WP_015637486.1 | RHS domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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