Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00237  |
| T6SS type | Type i2 |
| Strain | Salmonella enterica subsp. arizonae serovar 62:z4, z23:- str. RSK2980 |
| Replicon (RefSeq) | chromosome (NC_010067) |
| Location | 2504768..2560524 |
| Function | - |
| Comment | - |
| References | [1] Blondel CJ et al (2009) Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 0.6625. [PudMed:19653904] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 2 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| SARI_RS12035 | 2499893..2501056 | - | 1164 | WP_000835379.1 | acyl-CoA/acyl-ACP dehydrogenase | ||
| SARI_RS12040 | 2501066..2501911 | - | 846 | WP_001154293.1 | MaoC family dehydratase N-terminal domain-containing protein | ||
| SARI_RS12045 | 2501944..2502885 | - | 942 | WP_000157768.1 | FAD-binding protein | ||
| SARI_RS12050 | 2502896..2503645 | - | 750 | WP_000866756.1 | electron transfer flavoprotein subunit beta/FixA family protein | ||
| SARI_RS24480 | 2503682..2503852 | - | 171 | WP_176169250.1 | hypothetical protein | ||
| SARI_RS24485 | 2504476..2504565 | - | 90 | WP_134940432.1 | hypothetical protein | ||
| SARI_RS12055 | 2504694..2505850 | - | 1157 | pseudogene | IS3 family transposase | ||
| SARI_RS12065 (tssE) | 2505951..2506400 | - | 450 | WP_000375391.1 | type VI secretion system baseplate subunit TssE | ||
| SARI_RS12070 | 2506483..2506776 | - | 294 | WP_000095318.1 | bacteriocin immunity protein | ||
| SARI_RS12075 | 2506748..2508079 | + | 1332 | WP_052304240.1 | ISNCY family transposase | ||
| SARI_RS12080 | 2508186..2508449 | - | 264 | WP_001209969.1 | bacteriocin immunity protein | ||
| SARI_RS12085 | 2508556..2508819 | - | 264 | WP_000127331.1 | bacteriocin immunity protein | ||
| SARI_RS12095 | 2509270..2509638 | - | 369 | WP_000977990.1 | hypothetical protein | ||
| SARI_RS12100 | 2509635..2510504 | - | 870 | pseudogene | hypothetical protein | ||
| SARI_RS12105 | 2510504..2511521 | - | 1018 | pseudogene | DUF2345 domain-containing protein | ||
| SARI_RS12110 (tssE) | 2511552..2512001 | - | 450 | WP_001211319.1 | type VI secretion system baseplate subunit TssE | ||
| SARI_RS23045 | 2512386..2512754 | - | 369 | WP_103143143.1 | hypothetical protein | ||
| SARI_RS12120 | 2512777..2513761 | - | 985 | pseudogene | hypothetical protein | ||
| SARI_RS23885 | 2513934..2514257 | - | 324 | pseudogene | type VI secretion system tip protein VgrG | ||
| SARI_RS12130 | 2514257..2514730 | - | 474 | WP_000669944.1 | hypothetical protein | ||
| SARI_RS12135 | 2514733..2516382 | - | 1650 | WP_149022088.1 | DUF3289 family protein | ||
| T6CP002371 | TssI | SARI_RS12140 (vgrG) | 2516748..2519045 | - | 2298 | WP_000371004.1 | type VI secretion system tip protein VgrG |
| T6CP002372 | TssJ | SARI_RS12145 (tssJ) | 2519050..2519553 | - | 504 | WP_048908566.1 | type VI secretion system lipoprotein TssJ |
| T6CP009654 | TssE | SARI_RS12150 | 2519528..2519830 | - | 303 | pseudogene | GPW/gp25 family protein |
| SARI_RS12155 | 2519858..2520181 | - | 324 | WP_141024402.1 | bacteriocin immunity protein | ||
| T6CP002373 | TssI | SARI_RS23890 (vgrG) | 2520159..2523749 | - | 3591 | WP_000371003.1 | type VI secretion system tip protein VgrG |
| T6CP002374 | TssJ | SARI_RS12165 (tssJ) | 2523754..2524278 | - | 525 | WP_000246898.1 | type VI secretion system lipoprotein TssJ |
| T6CP002375 | TssG | SARI_RS12170 (tssG) | 2524314..2525396 | - | 1083 | WP_000090424.1 | type VI secretion system baseplate subunit TssG |
| T6CP002376 | TssF | SARI_RS12175 (tssF) | 2525360..2527129 | - | 1770 | WP_000342473.1 | type VI secretion system baseplate subunit TssF |
| T6CP008661 | TssA | SARI_RS12180 (tssA) | 2527163..2528770 | - | 1608 | WP_000097911.1 | type VI secretion system protein TssA |
| SARI_RS12185 | 2528818..2529717 | - | 900 | WP_149022081.1 | PASTA domain-containing protein | ||
| SARI_RS12190 | 2529750..2530934 | - | 1185 | WP_000679281.1 | tetratricopeptide repeat protein | ||
| SARI_RS23895 | 2530990..2532003 | - | 1014 | WP_001079319.1 | hypothetical protein | ||
| T6CP002377 | TssM | SARI_RS12200 | 2532006..2535377 | - | 3372 | WP_001151320.1 | type VI secretion protein VasK |
| SARI_RS12205 | 2535370..2536578 | - | 1209 | WP_001144697.1 | hypothetical protein | ||
| SARI_RS23055 | 2536581..2536844 | - | 264 | WP_024131989.1 | PAAR domain-containing protein | ||
| SARI_RS23900 | 2536988..2537500 | - | 513 | WP_000064654.1 | hypothetical protein | ||
| SARI_RS23905 | 2537800..2538201 | - | 402 | pseudogene | hypothetical protein | ||
| SARI_RS24490 | 2538198..2538757 | - | 560 | pseudogene | hypothetical protein | ||
| SARI_RS24870 | 2538740..2539600 | - | 861 | WP_012210479.1 | hypothetical protein | ||
| SARI_RS12230 | 2540289..2541818 | - | 1530 | pseudogene | hypothetical protein | ||
| SARI_RS12235 | 2541829..2542889 | - | 1061 | pseudogene | IS3 family transposase | ||
| T6CP011630 | PAAR | SARI_RS12245 | 2543015..2543278 | - | 264 | WP_012210483.1 | PAAR domain-containing protein |
| SARI_RS12250 | 2543411..2544241 | - | 831 | WP_149022082.1 | hypothetical protein | ||
| SARI_RS12255 | 2544273..2547371 | - | 3099 | WP_000125550.1 | glycoside hydrolase family protein | ||
| T6CP002378 | TssI | SARI_RS12260 (vgrG) | 2547387..2549744 | - | 2358 | WP_000093954.1 | type VI secretion system tip protein VgrG |
| T6CP002379 | TssH | SARI_RS12265 (tssH) | 2549741..2552413 | - | 2673 | WP_000399947.1 | type VI secretion system ATPase TssH |
| T6CP008662 | TssD | SARI_RS12270 | 2552577..2553068 | - | 492 | WP_001007312.1 | Hcp family type VI secretion system effector |
| T6CP011631 | TagL | SARI_RS12275 | 2553071..2554750 | - | 1680 | WP_001254769.1 | OmpA family protein |
| T6CP009307 | TssL | SARI_RS12280 | 2554750..2555439 | - | 690 | WP_001248376.1 | type VI secretion system protein TssL, short form |
| T6CP002380 | TssK | SARI_RS12285 (tssK) | 2555436..2556785 | - | 1350 | WP_000708640.1 | type VI secretion system baseplate subunit TssK |
| T6CP002381 | TssC | SARI_RS12290 (tssC) | 2556798..2558345 | - | 1548 | WP_048908568.1 | type VI secretion system contractile sheath large subunit |
| T6CP002382 | TssB | SARI_RS12295 (tssB) | 2558381..2558878 | - | 498 | WP_000785632.1 | type VI secretion system contractile sheath small subunit |
| SARI_RS12300 | 2559425..2560524 | - | 1100 | WP_134949391.1 | IS3 family transposase | ||
| SARI_RS24495 | 2560758..2560829 | + | 72 | pseudogene | SOS response-associated peptidase | ||
| SARI_RS12310 | 2561276..2562277 | + | 1002 | WP_001097570.1 | acyltransferase family protein | ||
| SARI_RS24875 | 2563986..2564444 | - | 459 | pseudogene | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01467 |
SARI_02603 | Tde | - | Salmonella enterica subsp. arizonae serovar 62:z4z23:- | chromosome (NC_010067) | 2520159..2523749 (-) | 160865837 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|